Cristina Gil
- Heart Failure Treatment and Management
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Chronic Disease Management Strategies
- Sepsis Diagnosis and Treatment
- RNA and protein synthesis mechanisms
- Congenital Heart Disease Studies
- Cardiovascular Conditions and Treatments
- SARS-CoV-2 and COVID-19 Research
- Potassium and Related Disorders
- Viral Infections and Immunology Research
- Mechanical Circulatory Support Devices
- Acute Myocardial Infarction Research
- Thermoregulation and physiological responses
- Muscle Physiology and Disorders
- Genomics and Rare Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Erythropoietin and Anemia Treatment
- Long-Term Effects of COVID-19
- vaccines and immunoinformatics approaches
- Gastrointestinal Tumor Research and Treatment
Universidad de Murcia
2022-2024
Universidad de Salamanca
2024
Complejo Hospitalario de Salamanca
2015-2023
Hospital Universitario Virgen de la Arrixaca
2020-2022
Instituto Murciano de Investigación Biosanitaria
2020-2022
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021-2022
Universitat de Barcelona
2021-2022
ERN GUARD-Heart
2020
Hospital Clínic de Barcelona
2017-2019
Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly variable and unpredictable severity. The presence frequent genetic single nucleotide polymorphisms (SNPs) population might lead to greater susceptibility infection or an exaggerated inflammatory response. SARS-CoV-2 requires ACE2 protein enter cell is regulator renin-angiotensin system. Accordingly, we studied associations between 8 SNPs from AGTR1, ACE genes severity produced virus. Methods 318 (aged...
Stringent variant interpretation guidelines can lead to high rates of variants uncertain significance (VUS) for genetically heterogeneous disease like long QT syndrome (LQTS) and Brugada (BrS). Quantitative disease-specific customization American College Medical Genetics Genomics/Association Molecular Pathology (ACMG/AMP) address this false negative rate.We compared rare frequencies from 1847 LQTS (KCNQ1/KCNH2/SCN5A) 3335 BrS (SCN5A) cases the International LQTS/BrS Consortia...
Background: Physical examination remains the cornerstone in assessment of acute heart failure. There is a lack adequately powered studies assessing combined impact both systolic blood pressure (SBP) and hypoperfusion on short-term mortality. Methods: Patients with failure from 41 Spanish emergency departments were recruited consecutively 3 time periods between 2011 2016. Logistic regression models used to assess association 30-day mortality SBP (<90, 90–109, 110–129, ≥130 mm Hg)...
Background: The aim of this study was to describe the prevalence and prognostic value most common triggering factors in acute heart failure. Methods: Patients with failure from 41 Spanish emergency departments were recruited consecutively three time periods between 2011 2016. Precipitating classified as: (a) unrecognized; (b) infection; (c) atrial fibrillation; (d) anaemia; (e) hypertension; (f) coronary syndrome; (g) non-adherence; (h) two or more precipitant factors. Unadjusted adjusted...
The coexistence of other comorbidities confers poor outcomes in patients with acute heart failure. Our aim was to determine the characteristics failure and cardiorenal anaemia syndrome relationship between renal dysfunction anaemia, alone or combined as syndrome, on short-term outcomes.We analysed Epidemiology Acute Heart Failure Emergency Departments registry (cohort Spanish emergency departments). Renal defined by an estimated glomerular filtration rate <60 ml/min/m2, haemoglobin values...
Abstract Aims To assess whether symptoms/signs of congestion and perfusion in acute heart failure (AHF) evaluated at patient arrival to the emergency department (ED) can predict severity decompensation short-term outcomes. Methods results We included patients from Epidemiology AHF Emergency Registry (EAHFE Registry). registered seven clinical surrogates five hypoperfusion. Patients were grouped according congestion/hypoperfusion. assessed need for hospitalization, in-hospital all-cause...
Abstract Background Acute heart failure (AHF) patients with high troponin levels have a worse prognosis. High‐sensitive T (hs‐TnT) has been used as tool to stratify prognosis in many scales but always qualitative and not quantitative variable. Objectives The main objective of this study was determine the best hs‐TnT cut‐off for prediction 30‐day all‐cause mortality. Methods EAHFE registry, prospective follow‐up cohort AHF, analysed. We performed propensity score analysis optimal point...
During the COVID-19 pandemic caused by SARS-CoV-2, new waves have been associated with variants and potential to escape vaccinations. Therefore, it is useful conduct retrospective genomic surveillance research. Herein, we present a detailed analysis of 88 SARS-CoV-2 genomes belonging samples taken from patients October 2020 April 2021 at "Reina Sofía" Hospital (Murcia, Spain) focused variant appeared later. The results mentioned stage show turning point since 20E (EU1) was still prevalent...