A5101406377- Pharmacological Effects of Natural Compounds
- Berberine and alkaloids research
- Synthesis and bioactivity of alkaloids
- Plant-based Medicinal Research
- Aquaculture Nutrition and Growth
- Cancer Research and Treatments
- Aquaculture disease management and microbiota
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Advanced Nanomaterials in Catalysis
- Analytical Chemistry and Chromatography
- Nanoplatforms for cancer theranostics
- Herbal Medicine Research Studies
- Cancer Cells and Metastasis
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Airway Management and Intubation Techniques
- Advanced battery technologies research
- Phytochemistry and biological activity of medicinal plants
- Lipid metabolism and disorders
- Artificial Intelligence in Healthcare and Education
- Tryptophan and brain disorders
- Infective Endocarditis Diagnosis and Management
- Nanoparticle-Based Drug Delivery
- Cardiac, Anesthesia and Surgical Outcomes
Shanxi Eye Hospital
2024
Northwest University
2024
Wenzhou Medical University
2018-2023
Chongqing University
2023
Jingdezhen Ceramic Institute
2023
Shanghai Sixth People's Hospital
2022
Shanghai Institute of Pharmaceutical Industry
2019
The oxidative stress amplifier CaO 2 /ICG@ZIF-8 was constructed by loading and ICG onto ZIF-8, achieving efficient photodynamic photothermal synergistic therapy -mediated cascades of oxygen production glutathione consumption.
The aim of this study was to establish a rapid, sensitive, and selective ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method quantify the concentrations licochalcone A applicate technique its pharmacokinetic study. Analytes were separated on an UPLC ethylene bridged hybrid (BEH) C18 column (2.1 mm × 50 mm, 1.7 μm). mobile phase consisted acetontrile 0.1% formic acid with flow rate 0.4 mL/min in gradient elution mode. Multiple-reaction monitoring (MRM) carried...
Transcriptome profiling of hepatocellular carcinoma (HCC) by next-generation sequencing (NGS) technology has been broadly performed previous studies, which facilitate our understanding the molecular mechanisms HCC formation, progression, and metastasis. However, few studies jointly analyze multiple types noncoding RNAs (ncRNAs), including long (lncRNAs), circular (circRNAs), micro-RNAs (miRNAs), further uncover their implications in HCC. In this study, we observed that circRNA cZRANB1 lncRNA...
A supramolecular and cell membrane co-modified drug delivery system was constructed to enhance Fe 3 O 4 SAS synergistically induced ferroptosis anti-tumor therapy.
Background: Modern pharmacological studies show that rhizoma coptidis has protective effects on the liver, gallbladder, kidney, cerebral ischemia-reperfusion, local hypoxia injury, antiinflammatory, bone nerve cells and myocardial cells. The effective components have been isolated from picroside I, II, III IV. Introduction: A selective sensitive ultra-performance liquid chromatography electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed for simultaneous...
Developing efficient bifunctional electrocatalysts for both the oxygen reduction reaction (ORR) and evolution (OER) is crucial large-scale application of rechargeable zinc–air batteries. Perovskite oxides are attractive candidates as electrocatalysts. Herein, Ln0.5Sr0.5CoO3-δ (Ln = La, Pr Sm) was prepared by sol-gel method evaluated ORR OER. Compare with La0.5Sr0.5CoO3-δ (LSC) Sm0.5Sr0.5CoO3-δ (SSC), Pr0.5Sr0.5CoO3-δ (PSC) demonstrated enhanced catalytic activity towards limiting current...
Background: The aim of this study was to determine the concentrations khasianine in mouse whole blood sample and its application for pharmacokinetics by a rapid, selective sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method. Methods: samples were preprocessed one-step protein precipitation with acetonitrile. performed on an ACQUITY I-Class UPLC system BEH column. Lannaconitine (internal standard, IS) gradient eluted mixture acetonitrile water 0.1%...
<title>Abstract</title> Introduction Endophthalmitis is a severe, vision-threatening intraocular infection that may follow various ophthalmic surgeries, with varying microbial etiologies. Abiotrophia defectiva, less commonly implicated pathogen, better recognized for its association endocarditis rather than infections. Case presentation A 50-year-old man was diagnosed endophthalmitis after trabeculectomy open-angle glaucoma. In the outpatient clinic, he had visual acuity of 20/160,...
Background: Xuezhikang capsule, which contains cholesterol synthase inhibitors and a large number of natural statins, is put in the clinical application lipid-lowering so on. However, specific use dose, effect relationship between metabolites are to be further studied. Introduction: Metabonomics study change quantity physiological changes from metabolites. At present metabolomics has been widely used drug development testing. In this study, we developed metabolomic method based on gas...
An ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was established to determine the hapepunine in mouse blood, and pharmacokinetics of after intravenous (1.0 mg/kg) intragastric (2.5, 5, 10 administrations studied. Delavinone used as an internal standard. The UPLC ethylene bridged hybrid (BEH) C18 column for chromatographic separation. mobile phase consisted acetonitrile 0.1% formic acid with a gradient elution flow rate 0.4 mL/min. Multiple reaction...
Abstract Calycanthine is an important class of alkaloids extracted and isolated from the roots, leaves, flowers fruits Chimonanthus praecox . In this work, UPLC-MS/MS method was used for determination calycanthine in rat plasma, pharmacokinetics rats were investigated. Midazolam as internal standard (IS), methanol precipitation to pretreatment plasma samples. Chromatographic separation achieved on a UPLC BEH C18 (50 × 2.1 mm, 1.7 μm) column with mobile phase methanol- 0.1% formic acid...
<p id="p00005">The valid prediction of unanticipated difficult tracheal intubation (DTI) is very important in clinic anesthesia. The purpose this study was to develop a machine learning model for predicting DTI. A comprehensive analysis two prospective observational airway research programs performed. In total, 3958 patients who underwent were included study. Data split into training set and test according 70%:30% randomly. XGBoost used F1 score as the main performance metric because data...