A5045868410- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Folate and B Vitamins Research
- Plant Disease Management Techniques
- Retinal Diseases and Treatments
- Enzyme Production and Characterization
- Plant Parasitism and Resistance
- Neurological Complications and Syndromes
- Chronic Kidney Disease and Diabetes
- Crop Yield and Soil Fertility
- Plant Reproductive Biology
- Rice Cultivation and Yield Improvement
- Plant responses to water stress
- Agricultural Science and Fertilization
- Plant Disease Resistance and Genetics
- Plant tissue culture and regeneration
- Microbial Metabolism and Applications
- Autophagy in Disease and Therapy
- Natural Antidiabetic Agents Studies
- Polysaccharides and Plant Cell Walls
- Plant-Microbe Interactions and Immunity
- Soil Carbon and Nitrogen Dynamics
- Silicon Effects in Agriculture
- Retinoids in leukemia and cellular processes
- Plant nutrient uptake and metabolism
Washington University in St. Louis
2025
Central Drug Research Institute
2024
Dr. Hari Singh Gour University
2020-2024
Agri Biotech Foundation
2021-2024
International Crops Research Institute for the Semi-Arid Tropics
2024
Banasthali University
2013-2024
University of Jammu
2023
Dr. Yashwant Singh Parmar University of Horticulture and Forestry
2022-2023
Northwestern University
2023
Guru Nanak Dev University
2011-2022
Salinity stress is a major constrain in the global rice production and hence serious efforts are being undertaken towards deciphering its remedial strategies. The comparative analysis of differential response salt sensitive tolerant lines judicious approach to obtain essential clues understanding acquisition salinity tolerance plants. However, adaptation fairly complex process operates through different mechanisms. Among various mechanisms involved, reactive oxygen species mediated believed...
Homocysteine (Hcy) is an amino acid that requires vitamins B12 and folic for its metabolism. Vitamins deficiencies lead to hyperhomocysteinemia (HHcy, elevated Hcy), which linked the development of diabetic retinopathy (DR), age-related macular degeneration (AMD), Alzheimer’s disease (AD). The goal current study was explore inflammation as underlying mechanism HHcy-induced pathology in age related diseases such AMD, DR, AD. Mice with HHcy due a lack enzyme cystathionine-β-synthase (CBS)...
Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) linked to vision loss in DR AMD. Our previous work revealed that HHcy altered BRB retinal endothelial cells vivo. Here we hypothesize homocysteine (Hcy) alters cell function angiogenic potential via activation oxidative stress. Human (HRECs) treated without different concentrations Hcy showed...
To study Hyperhomocysteinemia (HHcy)-induced epigenetic modifications as potential mechanisms of blood retinal barrier (BRB) dysfunction, retinas isolated from three- week-old mice with elevated level Homocysteine (Hcy) due to lack the enzyme cystathionine β-synthase (cbs-/- , cbs+/- and cbs+/+ ), human endothelial cells (HRECs), pigmented epithelial (ARPE-19) treated or without Hcy were evaluated for (1) histone deacetylases (HDAC), (2) DNA methylation (DNMT), (3) miRNA analysis....
The fungal disease, charcoal root rot, caused by Macrophomina phaseolina is a foremost yield restraining factor of Sorghum bicolor L. around the world. expression analysis genes induced in general defense response can endow with clues to reveal major mechanisms against pathogen infection sorghum plant. role chitinase and Stilbene synthase M. was studied under control growth conditions using real-time polymerase chain reaction. Here, we report antifungal two cultivars viz. PJ-1430 (resistant)...
Abstract Enormous amounts of keratinaceous waste make a significant and unexploited protein reserve that can be utilized through bioconversion into high-value products using microbial keratinases. This study was intended to assess the keratinase production from newly isolated B. velezensis NCIM 5802 proficiently hydrolyze chicken feathers. Incubation parameters used produce enzyme were optimized Response Surface Methodology (RSM) with feathers as substrate. Optimization elevated feather...
The timed contraction and relaxation of myofibers in tissues such as the heart skeletal muscle occurs via tightly regulated movement calcium ions into out sarcoplasmic reticulum (SR). In muscle, this phenomenon enables humans to exercise, perform day-to-day tasks, breathe. Sarcolipin, a small regulatory protein, prevents from entering SR by binding inhibiting SERCA, contributing myofiber contraction. Disruptions sarcolipin expression are implicated pathophysiology obesity musculoskeletal...
Glaucoma is a complex degenerative optic neuropathy characterized by loss of retinal ganglion cells (RGCs) leading to irreversible vision and blindness.
Clinical research in pediatric patients is necessary to develop safe and effective medicines for children. US Food Drug Administration (FDA) human subject protection regulations (21 Code of Federal Regulations 50, subpart D) require that, with limited exceptions, children that exceeds a defined level risk must offer prospect direct benefit the individual child sufficient justify those risks. Growing attention merits initiating clinical trials earlier drug biological product development...
Small GTP-binding proteins from the ADP-ribosylation factor (ARF) family are important regulators of vesicle formation and cellular trafficking in all eukaryotes. ARF activation is accomplished by a protein guanine nucleotide exchange factors (GEFs) that contain conserved catalytic Sec7 domain. Here, we identified characterized Secdin, small-molecule inhibitor Arabidopsis thaliana ARF-GEFs. Secdin application caused aberrant retention plasma membrane (PM) late endosomal compartments,...
Salinity stress is one of the major environmental challenges which adversely affects plant growth and productivity. The acquisition salinity tolerance has been an interesting area investigation for abiotic management. Recently, we investigated interdependency reactive oxygen species (ROS) generating scavenging system offering salt adaptation in rice. In continuation to our earlier findings, present study analyzed transcript level expression different respiratory burst oxidase homologs...
This study focuses on the efficient and cost-effective synthesis of silver nanoparticles (AgNPs) using plant extracts, which have versatile non-toxic applications. The research objectives include synthesizing AgNPs from readily available optimizing their production multi scale characterization, along with exploring use for enzyme immobilization mitigation poultry feather waste. Among extracts tested, flower extract Hibiscus rosa-sinensis (HF) showed most potential AgNP synthesis. HF-mediated...