Jiřı́ Friml

ORCID: 0000-0002-8302-7596
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About
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Research Areas
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • Plant nutrient uptake and metabolism
  • Photosynthetic Processes and Mechanisms
  • Cellular transport and secretion
  • Polysaccharides and Plant Cell Walls
  • Plant tissue culture and regeneration
  • Light effects on plants
  • Plant Parasitism and Resistance
  • Plant Stress Responses and Tolerance
  • Legume Nitrogen Fixing Symbiosis
  • Lipid Membrane Structure and Behavior
  • Plant Gene Expression Analysis
  • Plant-Microbe Interactions and Immunity
  • Plant Physiology and Cultivation Studies
  • Plant and animal studies
  • Plant responses to water stress
  • Peptidase Inhibition and Analysis
  • Microtubule and mitosis dynamics
  • RNA Research and Splicing
  • Calcium signaling and nucleotide metabolism
  • Phytoplasmas and Hemiptera pathogens
  • Plant Virus Research Studies
  • Plant and Biological Electrophysiology Studies
  • Endoplasmic Reticulum Stress and Disease

Institute of Science and Technology Austria
2016-2025

National Chung Hsing University
2024-2025

Shanghai Institute for Science of Science
2020-2024

Institute of Engineering Science
2020-2024

Institute of Science and Technology
2014-2024

Ghent University
2010-2022

VIB-UGent Center for Plant Systems Biology
2010-2022

University of Minnesota System
2021

Central European Institute of Technology – Masaryk University
2011-2020

Central European Institute of Technology
2011-2020

Intercellular flow of the phytohormone auxin underpins multiple developmental processes in plants. Plant-specific pin-formed (PIN) proteins and several phosphoglycoprotein (PGP) transporters are crucial factors transport-related development, yet molecular function PINs remains unknown. Here, we show that mediate efflux from mammalian yeast cells without needing additional plant-specific factors. Conditional gain-of-function alleles quantitative measurements accumulation Arabidopsis tobacco...

10.1126/science.1123542 article EN Science 2006-04-07

Polar flow of the phytohormone auxin requires plasma membrane-associated PIN proteins and underlies multiple developmental processes in plants. Here we address importance polarity subcellular localization for directionality transport Arabidopsis thaliana. Expression different PINs root epidermis revealed polar positions directional gravitropic growth. Interfering with sequence-embedded signals directly demonstrates that is a primary factor determining direction meristematic tissues. This...

10.1126/science.1121356 article EN Science 2006-04-07

Polar transport-dependent local accumulation of auxin provides positional cues for multiple plant patterning processes. This directional flow depends on the polar subcellular localization PIN efflux regulators. Overexpression PINOID protein kinase induces a basal-to-apical shift in localization, resulting loss gradients and strong defects embryo seedling roots. Conversely, pid function an apical-to-basal PIN1 targeting at inflorescence apex, accompanied by defective organogenesis. Our...

10.1126/science.1100618 article EN Science 2004-10-28

Abstract In plants, each developmental process integrates a network of signaling events that are regulated by different phytohormones, and interactions among hormonal pathways essential to modulate their effect. Continuous growth roots results from the postembryonic activity cells within root meristem is controlled coordinated action several including auxin ethylene. Although interaction has been studied intensively, molecular cellular mechanisms underlying this interplay unknown. We show...

10.1105/tpc.107.052126 article EN The Plant Cell 2007-07-01

Plant development displays an exceptional plasticity and adaptability that involves the dynamic, asymmetric distribution of phytohormone auxin. Polar auxin flow, which requires polarly localized transport facilitators PIN family, largely contributes to establishment maintenance gradients. Functionally overlapping action proteins mediates multiple developmental processes, including embryo formation, organ tropisms. Here we show exhibit synergistic interactions, involve cross-regulation gene...

10.1242/dev.02027 article EN Development 2005-09-28

Plants exhibit an exceptional adaptability to different environmental conditions. To a large extent, this depends on their ability initiate and form new organs throughout entire postembryonic life. Plant shoot root systems unceasingly branch axillary shoots or lateral roots, respectively. The first event in the formation of organ is specification founder cells. Several plant hormones, prominent among them auxin, have been implicated acquisition cell identity by differentiated cells, but...

10.1073/pnas.0712307105 article EN Proceedings of the National Academy of Sciences 2008-06-17

Abstract In Arabidopsis thaliana, lateral roots are formed from root pericycle cells adjacent to the xylem poles. Lateral development is regulated antagonistically by plant hormones auxin and cytokinin. While a great deal known about how promotes development, mechanism of cytokinin repression still unclear. Elevating levels was observed disrupt initiation regular pattern divisions that characterizes in Arabidopsis. To identify stage sensitive cytokinins, we targeted expression Agrobacterium...

10.1105/tpc.107.055863 article EN The Plant Cell 2007-12-01
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