A5087589231- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Supramolecular Chemistry and Complexes
- Metal-Organic Frameworks: Synthesis and Applications
- Molecular Sensors and Ion Detection
- Plant nutrient uptake and metabolism
- Legume Nitrogen Fixing Symbiosis
- Nuclear Materials and Properties
- Magnetism in coordination complexes
- Plant Molecular Biology Research
- Crystallography and molecular interactions
- Porphyrin and Phthalocyanine Chemistry
- Nematode management and characterization studies
- Plant Parasitism and Resistance
- Supramolecular Self-Assembly in Materials
- Nuclear reactor physics and engineering
- Plant Virus Research Studies
- Hydrogen embrittlement and corrosion behaviors in metals
- Plant-Microbe Interactions and Immunity
- Luminescence and Fluorescent Materials
- Plant Disease Management Techniques
- Plant Reproductive Biology
- Radioactive element chemistry and processing
- Protein Structure and Dynamics
- Garlic and Onion Studies
University of Warwick
2018-2024
DNV (Norway)
2024
The Ohio State University
2012-2024
Coventry (United Kingdom)
2020
University of Sheffield
2016
Donald Danforth Plant Science Center
2006-2012
Los Alamos National Laboratory
2012
The Kemp elimination (reaction of benzisoxazole with base to give 2-cyanophenolate) is catalyzed in the cavity a cubic M8L12 coordination cage because combination (i) binding driven by hydrophobic effect, and (ii) accumulation hydroxide ions around 16+ surface ion-pairing. Here we show how reaction cavity-bound guest modified presence other anions which can also accumulate displace hydroxide, inhibiting catalysis cage-based reaction. Addition chloride or fluoride inhibits extent that new...
Summary Amino acids represent the major form of reduced nitrogen that is transported in plants. acid transporters plants often show tissue‐specific expression patterns and are used by to transport these metabolites from source sink during development under changing environmental conditions. We identified one amino transporter, AtCAT6, which expressed tissues such as lateral root primordia, flowers seeds. Additionally AtCAT6 was induced infestation roots plant‐parasitic root‐knot nematode,...
Abstract Background Orobanchaceae is the only plant family with members representing full range of parasitic lifestyles plus a free-living lineage sister to all lineages, Lindenbergia . A generalist member this family, and an important model, Triphysaria versicolor regularly feeds upon wide host plants. Here, we compare de novo assembled transcriptomes generated from laser micro-dissected tissues at host-parasite interface uncover details largely uncharacterized interaction between plants...
Alkyl phosphonates bind in the cavities of cubic coordination cages <italic>via</italic> a range supramolecular interactions and cause luminescence quenching response.
Abstract The hydrophobic central cavity of a water‐soluble M 8 L 12 cubic coordination cage can accommodate range phospho‐diester and phospho‐triester guests such as the insecticide “dichlorvos” (2,2‐dichlorovinyl dimethyl phosphate) chemical warfare agent analogue di(isopropyl) chlorophosphate. accumulation hydroxide ions around cationic surface due to ion‐pairing in solution generates high local pH cage, resulting catalysed hydrolysis guests. A series control experiments unexpectedly...
Abstract The ability of an octanuclear cubic coordination cage to catalyse a nucleophilic aromatic substitution reaction on cavity‐bound guest was studied with 2,4‐dinitrofluorobenzene (DNFB) as the guest/substrate. It found that DNFB undergoes catalysed hydroxide ions within cavity (in aqueous buffer solution, pH 8.6). rate enhancement k cat /k uncat determined be 22, binding being required for catalysis occur. product, 2,4‐dinitrophenolate (DNP), remained bound due electrostatic...
The head-to-head oriented pair of melon resistance genes,
The root-knot nematode, Meloidogyne incognita, is an obligate parasite which depends entirely on the host plant for its nutrition. Root-knot nematodes induce formation of a highly specialized feeding site consisting several giant cells surrounded by network vascular tissues. Nutrients, including amino acids and sugars, are transferred apoplastically from tissues to site. Using Arabidopsis thaliana lacking vascular-expressed acid permeases (AAP) AAP3 or AAP6, we demonstrate that disruption...
In a coordination cage which contains an array of twelve naphthyl chromophores surrounding central cavity, photoinduced energy or electron-transfer can occur from the chromophore to bound guest in supramolecular host/guest complexes.
The octanuclear Co(ii) cubic coordination cage system H (or HW if it bears external water-solubilising substituents) has two types of binding site for guests. These are (i) the partially-enclosed central cavity where neutral hydrophobic organic species can bind, and (ii) six 'portals' in centres each faces anions bind via formation a network CH⋯X hydrogen bonds between anion CH units on positively-charged surface, as demonstrated by set crystal structures. near-orthogonality these guest...
We have performed a systematic investigation of the effects guest flexibility on their ability to bind in cavity coordination cage host water, using two sets isomeric aliphatic ketones that differ only branching patterns alkyl chains. Apart from expected increase binding strength for C
Abstract A crystallographic investigation of a series host–guest complexes in which small‐molecule organic guests occupy the central cavity an approximately cubic M 8 L 12 coordination cage has revealed some unexpected behaviour. Whilst form 1:1 H⋅G as we have seen before, extensive family bicyclic guests—including substituted coumarins and various saturated analogues—form 1:2 2 solid state, despite fact that solution titrations are consistent with complex formation, combined volume pair...
A heterometallic octanuclear coordination cage [Os4Zn4(Lnap)12]X16 (denoted Os•Zn; X = perchlorate or chloride) has been prepared (Lnap is a bis-bidentate bridging ligand containing two pyrazolyl-pyridine chelating units separated by 1,5-naphthalenediyl spacer group). The {Os(NN)3}2+ located at four of the eight vertices cube have long-lived, phosphorescent 3MLCT excited state which stronger electron donor than [Ru(bipy)3]2+. chloride form Os•Zn water-soluble and binds in its central cavity...
Cubic coordination cages encapsulate P–F containing guests and, when complexed, protect the bond from aqueous hydrolysis.
An octanuclear M8L12 coordination cage catalyses the Kemp elimination reaction of 5-nitro-1,2-benzisoxazole (NBI) with hydroxide to give 2-cyano-4-nitrophenolate (CNP) as product. In contrast previously-reported very efficient catalysis unsubstituted benzisoxazole, which involves substrate binding inside cavity, catalysed NBI is slower and occurs at external surface cage, even though can bind cavity. The rate sensitive presence added anions, 16+ surface, displacing ions from around are...
Tomato production in Ohio protected culture systems is hindered by a soilborne disease complex consisting of corky root rot (Pyrenochaeta lycopersici), black dot (Colletotrichum coccodes), Verticillium wilt (Verticillium dahliae), and root-knot (Meloidogyne hapla M. incognita). In survey 71 high tunnels, C. coccodes was detected 90% P. lycopersici (46%), V. dahliae (48%), Meloidogyne spp. (45%) were found nearly half tunnels. Anaerobic soil disinfestation (ASD) with wheat bran (20.2 Mg/ha)...
The aldol condensation of indane-1,3-dione (ID) to give ‘bindone’ in water is catalysed by an M8L12 cubic coordination cage (Hw). absolute rate reaction slow under weakly acidic conditions (pH 3–4), but the absence a catalyst it undetectable. In water, binding constant ID cavity Hw ca. 2.4 (±1.2) × 103 M−1, giving ∆G for −19.3 kJ mol−1. crystal structure complex revealed presence two molecules guest stacked inside cavity, packing coefficient 74% as well another molecule hydrogen-bonded...
All three diastereoisomers of a cuboctahedral coordination cage containing square and triangular faces, based on different chirality each face independently, have been structurally characterised.
In this work we compare and contrast the hydrolysis of two different aromatic esters using an octanuclear cubic Co
ABSTRACT Soil microbes are a major food source for free-living soil nematodes. It is known that certain bacteria have evolved systems to combat predation. We identified the nematode-antagonistic Pseudomonas protegens strain 15G2 from screening of microbes. Through protein purification we binary protein, designated Pp-ANP, which responsible nematicidal activity. This inhibits Caenorhabditis elegans growth and development by arresting larvae at L1 stage killing older-staged worms. The two...
The use of organophosphorus chemical warfare agents still remains an ongoing global threat. Here we investigate the binding small-molecule organic guests including phosphate esters, sulfonate carbonate esters and a sulfite ester - some which act as simulants for in cavity water-soluble coordination cage. For several these guest species, constants range 10
Coordination cages are well-known to act as molecular containers that can bind small-molecule guests in their cavity. Such cavity binding is associated with interactions of the surrounding set surfaces define cavity; a guest good fit for will have many favourable interior host. As exterior well surfaces, possibilities also exist ‘guests’ not well-bound interact surface cage where spatial constraints fewer. In this paper, we report combined solid-state and solution study using an octanuclear...