A5100721443- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Plant Reproductive Biology
- Metabolism and Genetic Disorders
- Plant responses to water stress
- Legume Nitrogen Fixing Symbiosis
- Plant Stress Responses and Tolerance
- Mitochondrial Function and Pathology
- Photosynthetic Processes and Mechanisms
- Polysaccharides and Plant Cell Walls
- High-Energy Particle Collisions Research
- Particle physics theoretical and experimental studies
- Light effects on plants
- Plant tissue culture and regeneration
- Rice Cultivation and Yield Improvement
- Diet and metabolism studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Peroxisome Proliferator-Activated Receptors
- RNA Interference and Gene Delivery
- Folate and B Vitamins Research
- Quantum Chromodynamics and Particle Interactions
- Biochemical and Molecular Research
- Vector-borne infectious diseases
- Poxvirus research and outbreaks
University of Nottingham
2016-2025
UMR Botanique et Modélisation de l’Architecture des Plantes et des végétations
2023
LMI Adaptation des Plantes et Microorganismes Associés aux Stress Environnementaux
2023
Centre d'Etude Regional pour l'Amelioration de l'Adaptation a la Secheresse
2023
Montpellier GenomiX
2023
International Crops Research Institute for the Semi-Arid Tropics
2023
Centre National de la Recherche Scientifique
2023
Laboratoire Génome et Développement des Plantes
2023
Institut de Recherche pour le Développement
2007-2023
Université de Perpignan
2023
Lateral root development inArabidopsis provides a model for the study of hormonal signals that regulate postembryonic organogenesis in higher plants.Lateral roots originate from pairs pericycle cells, several cell files positioned opposite xylem pole, initiate series asymmetric, transverse divisions.The auxin transport inhibitor N -1-naphthylphthalamic acid (NPA) arrests lateral by blocking first division(s).We investigated basis NPA action using cell-specific reporter to demonstrate pole...
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant growth phenotype abolish gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that mediates transport of acid-like signaling molecule. Indole-3-acetic acid, major form in higher plants, is structurally similar tryptophan a likely substrate for product. cloned can restore...
Recent evidence has defined an important role for PPARα in the transcriptional control of cardiac energy metabolism. To investigate genesis metabolic and functional derangements diabetic cardiomyopathy, mice with cardiac-restricted overexpression (MHC-PPAR) were produced characterized. The expression target genes involved fatty acid uptake oxidation pathways was increased MHC-PPAR mice. Surprisingly, glucose transport utilization reciprocally repressed hearts. Consistent gene profile,...
Auxins represent an important class of plant hormone that regulate development. Plants use specialized carrier proteins to transport the auxin indole-3-acetic acid (IAA) target tissues. To date, efflux carrier-mediated polar has been assumed sole mode long distance IAA movement. Localization permease AUX1 in Arabidopsis root apex revealed a novel phloem-based pathway. AUX1, asymmetrically localized plasma membrane protophloem cells, is proposed promote acropetal, post-phloem movement apex....
In plants, the developmental mechanisms that regulate positioning of lateral organs along primary root are currently unknown. We present evidence on how initiation is controlled in a spatiotemporal manner model plant Arabidopsis thaliana. First, roots spaced main axis regular left-right alternating pattern correlates with gravity-induced waving and depends AUX1, an auxin influx carrier essential for gravitropic response. Second, we found priming pericycle cells might take place basal...
Germline mutations in the tumour suppressor gene PTEN have been implicated two hamartoma syndromes that exhibit some clinical overlap, Cowden syndrome (CS) and Bannayan-Riley-Ruvalcaba (BRR). maps to 10q23 encodes a dual specificity phosphatase, substrate of which is phosphatidylinositol 3,4,5-triphosphate, phospholipid 3-kinase pathway. CS characterized by multiple hamartomas an increased risk benign malignant disease breast, thyroid central nervous system, whilst presence cancer has not...
Abstract In Arabidopsis thaliana, lateral roots are formed from root pericycle cells adjacent to the xylem poles. Lateral development is regulated antagonistically by plant hormones auxin and cytokinin. While a great deal known about how promotes development, mechanism of cytokinin repression still unclear. Elevating levels was observed disrupt initiation regular pattern divisions that characterizes in Arabidopsis. To identify stage sensitive cytokinins, we targeted expression Agrobacterium...
Abstract Ethylene represents an important regulatory signal for root development. Genetic studies in Arabidopsis thaliana have demonstrated that ethylene inhibition of growth involves another hormone signal, auxin. This study investigated why auxin was required by to regulate growth. We initially observed positively controls biosynthesis the apex. subsequently ethylene-regulated is dependent on (1) transport from apex via lateral cap and (2) responses occurring multiple elongation zone...
Arabidopsis root architecture is regulated by shoot-derived signals such as nitrate and auxin. We report that mutations in the putative auxin influx carrier AUX1 modify a result of disruption hormone transport between indole-3-acetic acid (IAA) source sink tissues. Gas chromatography–selected reaction monitoring–mass spectrometry measurements revealed aux1 mutant exhibited altered IAA distribution young leaf tissues, major organs, respectively, developing seedling. Expression studies using...
Summary Lateral root formation is profoundly affected by auxins. Here we present data which indicate that light influences the of indole‐3‐acetic acid (IAA) in germinating Arabidopsis seedlings. IAA transported from developing leaves to system detectable as a short‐lived pulse roots and required for emergence lateral primordia (LRP) during early seedling development. LRP inhibited removal apical tissues prior detection root, but this treatment has minimal effects on initiation. Our results...
Auxin regulates most aspects of plant growth and development. The hormone is perceived by the TIR1/AFB family F-box proteins acting in concert with Aux/IAA transcriptional repressors. Arabidopsis plants that lack members are auxin resistant display a variety defects. However, little known about functional differences between individual family. Phylogenetic studies reveal conserved across land lineages fall into four clades. Three these subgroups emerged before separation angiosperms...