- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Genetics and Biotechnology
- Bacterial Identification and Susceptibility Testing
- Genomics and Phylogenetic Studies
- Kidney Stones and Urolithiasis Treatments
- Infections and bacterial resistance
- Rabies epidemiology and control
- Liver Disease Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Legionella and Acanthamoeba research
- Hepatitis C virus research
- Antifungal resistance and susceptibility
- Parasitic Infections and Diagnostics
- Orthopedic Infections and Treatments
- Vibrio bacteria research studies
- Pelvic floor disorders treatments
- Infective Endocarditis Diagnosis and Management
- Neonatal and Maternal Infections
- Genomics, phytochemicals, and oxidative stress
- Clinical Laboratory Practices and Quality Control
- Paleopathology and ancient diseases
- Yersinia bacterium, plague, ectoparasites research
- Streptococcal Infections and Treatments
Zhejiang University
2021-2024
Jinhua Central Hospital
2020-2024
Second Affiliated Hospital of Zhejiang University
2021-2022
TMexCD1-TOprJ1, which is associated with phenotypic resistance to multiple classes of antibiotics, a transmissible resistance-nodulation-division (RND) family efflux pump. However, the prevalence and genomic characteristics clinical isolates this important determinant are poorly understood. In study, we aimed survey tmexCD-toprJ among Gram-negative collected from hospitals in China between 1991 2020 characterise tmexCD-toprJ-positive isolates.We conducted online data retrieval active...
Acinetobacter baumannii is one of the key Gram-negative pathogens that can cause serious nosocomial infections. In China, a large proportion clinical A. strains are multidrug resistant, among which resistant to carbapenems particularly worrisome, as infections caused by such may limit choice existing antibiotics. We conducted nationwide and genome-based surveillance on prevalence antibiotic susceptibility profile carbapenem-resistant (CRAB) collected from intensive care units (ICUs) in...
The increased carbapenem resistance among Pseudomonas aeruginosa has become a serious health issue worldwide. We reported an extensively drug-resistant (XDR) P. PA30 isolate which belonged to sequence type ST463 and contained IncP-2 plasmid (pPA30_1) carrying two genes, namely, blaIMP-45 blaAFM-1, encoded the metallo-β-lactamases AFM-1 IMP-45, respectively. Additionally, strain had (pPA30_2) with copies of blaKPC-2 genes embedded. pPA30_1 was highly similar previously pHS17-127, same genetic...
We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from fecal specimen a patient in China.The OXA-181-encoding gene bla OXA-181 was located on 51 kb IncX3-type plasmid.Conjugation assay and wholegenome sequencing analysis revealed that this transferrable plasmid K. isolate might have originated Escherichia coli potential to mediate spread .
CG258 is the dominant carbapenemase-producing Klebsiella pneumoniae clone worldwide and treatment of infections caused by this relies largely on last-line antibiotics, colistin, tigecycline. However, emergence global dissemination mcr tmexCD1-toprJ1 genes have significantly compromised their clinical applications. K. carrying both not been reported. A colistin-resistant strain T698-1 belonging to ST1326, a member CG258, was isolated from intestinal sample patient characterized antimicrobial...
Abstract Background Vogesella species are common aquatic, Gram-negative rod-shaped bacteria, originally described in 1997. perlucida was first isolated from spring water 2008. Furthermore, bacterial pathogenicity of has never been reported. Here, we report the case rare -induced bacteremia an advanced-age patient with many basic diseases and history dexamethasone abuse. Case presentation A 71-year-old female admitted inflamed upper lower limbs, rubefaction, pain fever (about 40 °C). She had...
Bloodstream infections (BSI) are associated with high morbidity and mortality remain a leading cause of death. Blood culture (BC) including the identification antimicrobial susceptibility testing causative microorganisms should be performed as soon possible. In this study, we developed an in-house rapid (rAST) protocol for positive BC. First, rAST was in simulated BC standard strains ( Escherichia coli ATCC 25922, Staphylococcus aureus 25923, Pseudomonas aeruginosa 27853) at three different...