- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Seaweed-derived Bioactive Compounds
- Microbial Natural Products and Biosynthesis
- Polysaccharides Composition and Applications
- Polydiacetylene-based materials and applications
- Bee Products Chemical Analysis
- Cyclopropane Reaction Mechanisms
- Essential Oils and Antimicrobial Activity
- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Selenium in Biological Systems
- Algal biology and biofuel production
- Microencapsulation and Drying Processes
- Electrochemical sensors and biosensors
- Biochemical and Structural Characterization
- melanin and skin pigmentation
- Circular RNAs in diseases
- Proteoglycans and glycosaminoglycans research
- IL-33, ST2, and ILC Pathways
- Medicinal plant effects and applications
- Nanocomposite Films for Food Packaging
- Calcium Carbonate Crystallization and Inhibition
- Pregnancy-related medical research
- Fermentation and Sensory Analysis
Zhengzhou University of Light Industry
2015-2025
China Medical University
2025
Changzhou University
2024
Hebei Medical University
2023
Fourth Hospital of Hebei Medical University
2023
Wuhan University
2008-2014
In this study, a flavor imitation method for Osmanthus fragrans aroma was developed based on molecular docking screening and odor activity value (OAV) analysis. A range of 41 volatile compounds defined through headspace solid-phase microextraction (HS-SPME) analysis O. dry powders gas chromatography-mass spectrometry (GC-MS) determination its essential oil. Molecular performed using these with ten chosen olfactory receptors (ORs) related to floral aroma, heat map constructed the cluster...
Two polysaccharide fractions were successfully isolated from the crude exopolysaccharide (EPS) of Scleroderma areolatum via gel filtration chromatography. Size exclusion chromatography/multi-angle laser light scattering (SEC/MALLS) analysis showed that weight average molecular weights (Mw) these was 3.162 ȕ 106 (Fr-I) and 2.613 (Fr-II). Both EPS exhibited a compact globular structure in aqueous solution. Monosaccharide composition revealed they primarily composed mannose glucuronic acid....
Gut microbiome influences tumorigenesis and tumor progression through regulating the microenvironment (TME) modifying blood metabolites. However, mechanisms by which gut metabolites regulate TME in multiple myeloma (MM) remain unclear. By employing16S rRNA gene sequencing coupled with metagenomics ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry, we find that Lachnospiraceae are high phosphatidylcholine (PC) low MM patients. We further show inhibits PC...
We report on a green procedure for the synthesis and stabilization of gold nanoparticles (AuNPs) from chlorauric acid (HAuCl4) with use β-glucan known as Lentinan (LNT) without external reducing or stabilizing agents in aqueous medium. LNT adopted triple helical conformation water, which was first denatured into single chains (s-LNT) at high temperature 140 °C before mixing HAuCl4. Results UV–vis absorption spectroscopy, transmission electron microscopy (TEM), energy dispersive X-ray (EDX)...
Tebuconazole is a chiral triazole fungicide used globally in agriculture as racemic mixture, but its enantiomers exhibit significant enantioselective dissimilarities bioactivity and environmental behaviors. The steric hindrance caused by the tert-butyl group makes it great challenge to synthesize tebuconazole enantiomers. Here, we designed simple chemoenzymatic approach for asymmetric synthesis of (R)-tebuconazole, which includes biocatalytic resolution epoxy-precursor...
An acidic extracellular polysaccharide (EPS) was gained from Stropharia rugosoannulata fermentation broth by the alcohol precipitate method. Sulfated derivative of EPS (S-EPS) chlorosulfonic acid-pyridine method and conditions were as follows: pyridine reaction solvent, temperature 80 °C, time 90 min. The chemical structure chain conformation S-EPS characterized FT-IR, NMR size exclusion chromatography (SEC) coupled with multi-angle laser light scattering (MALLS) detection. FT-IR spectra...
The effect on different three carbon source (i.e. glucose, fructose and sucrose) production, chemical characterization antioxidant activity of exopolysaccharide (EPS) produced by Phellinus vaninii Ljup was investigated in this study. Amongst sources examined, glucose sucrose were favorable for the mycelia growth, while maximum EPS yield achieved when employed. predominant carbohydrate compositions EPSs identified gluconic acid, mannose galactose acid. Then, FT-IR spectral analysis revealed...
A water-soluble polysaccharide (GLP-2) was isolated and purified from Ganoderma lucidum by the microwave-assisted freeze-thaw method. Microwave-assisted rapid thawing treatment can greatly improve extraction yield of polysaccharides. The chemical structure GLP-2 analyzed with FT-IR, HPLC, GC-MS, NMR spectrometry. It proved that is mainly composed β-1,3-glucose β-1,6-glucose. chain conformation SEC-MALLS-RI, indicating adopts semi-rigid conformation. Its molecular weight 16.7 × 104, its size...
Two new compounds, versicolones A and B (1 2), three known pyrone derivatives (3-5) were isolated from the insect-associated fungus Aspergillus versicolor. Their structures elucidated through a combination of HRESIMS NMR spectroscopic analysis. Versicolone (1) was revealed as coumarin derivative with rare 5-alkyl side chain substitution. Compound 5 exhibited significant antioxidant activity EC50 value 8.0 μM in ABTS (2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) assay, which more...
Novel protein-based nanocomposites were well prepared by in vivo synthesis and co-precipitation of soy protein isolate (SPI) with calcium carbonate (CaCO3) an aqueous solution. The resultant CaCO3 the was identified as calcite- aragonite-type, respectively. morphology structure CaCO3/SPI composites investigated means wide-angle X-ray diffraction, Fourier transform infrared spectra, scanning electron microscopy, high-resolution transmission microscopy. results revealed that polymorph size...
Background: Phellinus vaninii, a medicinal basidiomycete fungus, is often confused with igniarius and linteus. Polysaccharides extract from P. linteus are reported to stimulate humoral immunity inhibit tumor growth However, available literature reviewed no information on the relationship between bioactivities structures of polysaccharides fruit body vaninii. Methods: Two water-soluble (PV-W, PV-B) were isolated purified fruiting bodies vaninii by hot water sodium hydroxide solution,...
Extracellular polysaccharide from Pleurotus eryngii was sulfated; the optimum reaction conditions used pyridine as solvent, a temperature of 80°C, and time 90 minutes. The structure antioxidant activity sulfated original polysaccharides (designated SF-1 Fr-1, respectively) were investigated. main functional groups determined by Fourier transform infrared, chain conformation size-exclusion chromatography with laser light scattering viscometry. infrared spectra indicated that group linked to...
Three new macrocyclic trichothecenes possessing rare 6′-ketal moieties, roridoxins A–C (1–3), and five known compounds (4–8) were isolated from the insect-associated fungus Myrothecium roridum. Their structures confirmed by a combination of NMR HRESIMS data, while their absolute configurations unambiguously determined single-crystal X-ray analysis electronic circular dichroism experiments. Trichothecenes 1 3 showed potent antifungal activities against four strains phytopathogenic fungi. In...
Flutriafol, a globally utilized triazole fungicide in agriculture, is typically applied as racemic mixture, but its enantiomers differ bioactivity and environmental impact. The synthesis of flutriafol critically dependent on chiral precursors: 2,2-bisaryl-substituted oxirane [(2-fluorophenyl)-2-(4-fluorophenyl)oxirane,
Abstract Compared with peppermint oil, natural has more ingredients, a layered fragrance, and green colour. It been widely used as nutritional additive, herbal tea, food flavouring or colouring. In this work, the retention of volatile flavour compounds powders was enhanced by propylene glycol, reagent that enhances hydrogen bonds moisture absorption. The levels influence glycol content on different compounds, absorption water distribution were evaluated GC–MS, dynamic instrument (DVS),...
The antibacterial secondary metabolites of the fungus Penicillium chrysogenum associated with beetle Aspongopus chinensis were investigated through chromatographic fractionation methods ethyl acetate extracts fungal cultures. Five compounds isolated, and their structures determined as emodin, 4-(methoxymethyl)benzoic acid, isoochracinic secalonic acid D, dicerandrol A using mass spectroscopy nuclear magnetic resonance spectroscopic analyses. Emodin exhibited strong antimicrobial activity,...
The effects of carbon source on properties and bioactivities exopolysaccharide (EPS) produced by Trametes ochracea were investigated in this study. results indicated that EPS production varied with five different sources. After a fermentation period 8 days, sucrose was the most suitable for biomass production. predominant carbohydrate compositions EPSs identified glucose mannose. fermented has highest content. Then, FT-IR spectral analysis revealed prominent characteristic groups EPSs. Each...