A5084985976- Advancements in Transdermal Drug Delivery
- Drug Solubulity and Delivery Systems
- Computational Drug Discovery Methods
- Pharmacological Effects of Natural Compounds
- Chemotherapy-related skin toxicity
- Moringa oleifera research and applications
- Insect Resistance and Genetics
- Natural Antidiabetic Agents Studies
- Diverse Scientific Research Studies
- Intramuscular injections and effects
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Ziziphus Jujuba Studies and Applications
- Pharmacological Effects and Assays
- Mass Spectrometry Techniques and Applications
- Chromatography in Natural Products
- Ginger and Zingiberaceae research
- Gout, Hyperuricemia, Uric Acid
- Phytochemistry and Bioactive Compounds
- Genetics and Plant Breeding
- Medicinal plant effects and applications
- Research in Cotton Cultivation
- Plant nutrient uptake and metabolism
- Pharmacological Effects of Medicinal Plants
- Phytochemicals and Antioxidant Activities
University of Azad Jammu and Kashmir
2024
Centre of Excellence in Molecular Biology
2022-2023
University of Karachi
2023
University of the Punjab
2017-2023
Combined Military Hospital
2022
National University of Medical Sciences
2022
CMH Lahore Medical College and Institute of Dentistry
2018
National Institute of Technology Warangal
2013
Abstract Cysteine-rich receptor-like-kinases ( CRKs ), a transmembrane subfamily of receptor-like kinase, play crucial roles in plant adaptation. As such cotton is the major source fiber for textile industry, but environmental stresses are limiting its growth and production. Here, we have performed deep computational analysis five Gossypium species, including G. arboreum (60 genes) , raimondii (74 herbaceum (65 hirsutum (118 genes), barbadense (120 genes). All identified were classified into...
The study was aimed at designing and characterizing the ondansetron hydrochloride (OND) bearing agarose (AG), hydroxypropyl methyl cellulose (HPMC) mucoadhesive buccal films employing glycerol as a plasticizer. delivery of remarkably boosted by physical (iontophoresis) chemical enhancement approaches (chemical penetration enhancers). To explore influence different formulation components, i.e., agarose, (HPMC), on various evaluating parameters, tensile strength, swelling index, ex vivo...
The aim of this study is to evaluate the adhesion ability okra gum, which gaining popularity as a tablet binder. For purpose, gum was extracted from pods, and binding strength different concentrations (1%, 3%, 5%) determined quantitatively. Additionally, naproxen sodium tablets were prepared by using binder evaluated for their properties including hardness, friability, disintegration time, dissolution rate. values compared with that pre-gelatinized starch, commonly used results universal...
Nature represents a basic source of medicinal scaffolds that can develop into potent drugs used in the treatment many diseases.The present study was planned to evaluate combined effects polyherbal methanolic extract herbs (fruit capsicum, bark cinnamon, rhizome turmeric and ginger) were individually well known for their analgesic anti-inflammatory activities. Furthermore, we aimed hydrogel formulation this characterize its potential.Zingiber officinale (R.), Capsicum annuum (L.), Curcuma...
Common methodologies such as liquid-liquid extraction and solid-phase are applied for the of opioids from biological specimens i.e., blood urine. Techniques including LC-MS/LC-MSMS, GC-MS, etc. used qualitative or quantitative determination opioids. The goal present work is to design a green, economic, rugged, simple technique famous in human urine their simultaneous quantification by GC-MS equipped with an inert plus electron impact (EI) ionization source at SIM mode produce reproducible...
The aim of present study is to emphasize the phytochemical and biological studies root extracts Bryophyllum pinnatum, as little work was documented on roots.Phytochemical analysis powder were evaluated by standard methods.UV/ Visible scanning, FTIR atomic absorption spectroscopy also performed for purposes standardization.In vitro anti-inflammatory investigation done protein denaturation method xanthine oxidase inhibition assay confirm anti-gout effect.Phytochemical results revealed presence...
The rhizomes of Bergenia ciliata (B. ciliata, Family: Saxifragaceae) are widely used for treating gastric ulcers in folk medicine Asia. It was hypothesized that anti-ulcer activity B. is due to its anti-Helicobacter pylori (H. pylori) activity. anti-H. investigated on six clinical bacterial isolates using agar well-diffusion and broth micro-dilution methods. amoxicillin (standard) the highest (Zone inhibition; ZI = 25 mm, minimum inhibitory concentration; MIC=0.125 µg/µL) whereas among all...
Purpose: To evaluate 5-Benzyl-1,3,4-oxadiazole-2-thiol (OXPA) for antidiabetic and antioxidant properties.
 Methods: Antidiabetic activity was evaluated using three in vitro models, glucose uptake by yeast cells, alpha amylase inhibition assay hemoglobin glycosylation assays. Antioxidant potential determined DPPH radical scavenging, reducing power lipid peroxidation assays.
 Results: OXPA showed all the models. The of compound comparable with that metronidazole but slightly lower...
The conventional dosage forms (tablets, capsules) of ibuprofen have less potential in the suppression pain and inflammation due to their slow dissolution rates lower bioavailability. aim this study was fabricate fibrous solid dispersion for improved rate quick therapeutic action. Drug-loaded microfibers were fabricated using centrifugal melt spinning (CMS) technique from physical mixture sucrose, a hydrophilic polymer, PVP. These fibers characterized by SEM, PXRD, DSC, FTIR spectroscopy....
Object tracking is one of the important tasks in field computer vision.Some areas which need Visual object are surveillance, automated video analysis, etc. Mean shift algorithm popular techniques for this task and advantageous when compared to some other methods.But method would not be appropriate case large target appearance changes occlusion.In addition, fails under action non-linear forces like that gravity e.g. a ball falling gravity.Another used uses Kalman filter, with measurements...
State Biosphere Reserve Neelum (SBRN) is located in northern side of state Azad Jammu and Kashmir (AJK) Pakistan.It a representative region having an important geographical position being at Line Control.It shares its border with Indian Occupied due to prevailing uncertain ground conditions the past did not allow get explore this area for Odonata species complex.In study first time detailed surveys were conducted exploring diversity both sub orders (Anisoptera Zygoptera) during summer season...
Recently, a traditional remedy (Joshanda) has been replaced largely by modern ready-to-use dosage forms, which have not compared to the original remedy. Therefore, present study aimed compare number of forms with Seven brands, 3 batches each, were Lab-made formulation reference analytical (proximate analyses, spectroscopic and chromatographic metabolomes) pharmacological profiles (anti-inflammatory antibacterial activities). Chemical differences found between Joshanda forms. Such variations...
Breast cancer presents a serious public health risk in both developed and developing countries. The ACE gene, which is located chromosome 17q23, has many polymorphisms. most commonly studied 287 bp Alu insertion/deletion (I/D) polymorphism intron 16 that accounts for 50% of the variability circulating levels. main aim this study to find out association gene with breast Pakistani population. Experimental cross-sectional. A total 186 samples were collected. Of 186, 93 taken as healthy controls...