- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Platelet Disorders and Treatments
- Immune cells in cancer
- Tailings Management and Properties
- Environmental Toxicology and Ecotoxicology
- Mesenchymal stem cell research
- Lymphoma Diagnosis and Treatment
- Kruppel-like factors research
- Geotechnical Engineering and Soil Mechanics
- Diabetes Treatment and Management
- Pharmaceutical and Antibiotic Environmental Impacts
- Metabolism, Diabetes, and Cancer
- Blood groups and transfusion
- Chronic Lymphocytic Leukemia Research
- FOXO transcription factor regulation
- Sarcoma Diagnosis and Treatment
- Pesticide and Herbicide Environmental Studies
- Immune Cell Function and Interaction
- Dam Engineering and Safety
Second Hospital of Shandong University
2024
Shandong University
2024
Heze Municipal Hospital
2008-2024
Shandong First Medical University
2023
Qilu Hospital of Shandong University
2020-2023
Taian City Central Hospital
2023
Liaocheng People's Hospital
2023
Kunming Institute of Precious Metals
2021
Central South University
2021
Wuhan Modern Urban Agriculture Planning and Design Institute
2016
Trichlorfon (TCF) is an important organophosphate pesticide in agriculture. However, limited information known about the biodegradation behaviors and kinetics of this pesticide. In study, a newly isolated fungus (PA F-2) from pesticide-polluted soils was identified as Aspergillus sydowii on basis sequencing internal transcribed spacer rDNA. This degraded TCF sole carbon, phosphorus, carbon–phosphorus sources mineral salt medium (MSM). Optimal degradation conditions were determined through...
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy, whose immunological mechanisms are still partially uncovered. Regulatory B cells (Bregs) and CD4+ regulatory T (Tregs) subgroups of immunoregulatory involved in modulating autoimmunity, inflammation, transplantation reactions. Herein, by studying the number function Breg Treg cell subsets patients with AML, we explored their potential role pathogenesis AML. Newly diagnosed AML patients, complete remission, healthy...
<title>Abstract</title> <bold>[Objectives]</bold>This study aimed to investigate the beneficial effects of iron isomaltoside (IIM) on myocardial function and associated mechanisms in rats with ischemia/reperfusion (I/R)-induced damage hypoxia/reoxygenation (H/R)-induced H9C2 cells.<bold>[Design & Methods]</bold>Changes cardiac pathology after infarction (MI) were analyzed hematoxylin-eosin staining. Myocardial cellapoptosis heart tissues MI was assessed using TUNEL In H/R-induced cells,...
Summary Corticosteroids are the standard first‐line treatment for primary immune thrombocytopenia (ITP), with a high initial response but unsatisfactory sustained (SR). Additionally, corticosteroids usually lead to hyperglycaemia especially in patients pre‐existing type 2 diabetes mellitus (T2DM). Besides reducing blood glucose levels, metformin was found have immunomodulatory effects. We hereby conducted multicentre propensity score matching analysis of plus versus newly diagnosed ITP T2DM....
Abstract The mutation landscapes and clinical significance of clonal hematopoiesis (CH) in idiopathic cytopenia undetermined (ICUS) is still unclear. Based on the next-generation sequencingdata 281 ICUS patients, we sought to depict profile CH evaluate its role disease progression. It was found that occurred 27% more prevalent male patients. incidence accumulated with age. AXSL1 , DNMT3A U2AF1 TET2 were most frequently mutated genes. Exclusive mutations existed co-occurring between SRSF2 WT1...
Mesenchymal stem cell(MSC)have been identified in animals.As cells.thev have the a-bility to differentiate into multiple cell types,such as bone,fat and cartilage cells.This potentiaJ might pro-vide exciting therapeutic possibilities. MSC prerentially home damaged tissue may potential.In vitro data suggested that had low inherent immunogenicity they induce little,if any,proliferation of allogeneic lymphocytes.Instead,MSC appear be immunosuppressive vitro.They can in-hibit T-cell...
Abstract The normal operation of Yulangpei tailings reservoir is affected by landslide stability. In this paper, taking the main and side slopes near dam bank ditch as an example, water-soil coupling theory applied to comprehensively evaluate reliability reservoir. Grading seepage prevention (GSP) measures suction substrate are considered, well infiltration different rainfall water levels. We numerically simulate typical three forms under conditions conduct a reliable comprehensive...