A5013477909- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Mechanical Circulatory Support Devices
- Liver Disease and Transplantation
- Cardiac Ischemia and Reperfusion
- Congenital Anomalies and Fetal Surgery
- Organ Transplantation Techniques and Outcomes
- Urological Disorders and Treatments
- Cardiac Arrest and Resuscitation
- Healthcare Technology and Patient Monitoring
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Non-Invasive Vital Sign Monitoring
- Trauma Management and Diagnosis
- Transplantation: Methods and Outcomes
- Molecular spectroscopy and chirality
- Silicon Carbide Semiconductor Technologies
- Intensive Care Unit Cognitive Disorders
- Pediatric Pain Management Techniques
- Polymer Surface Interaction Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal Transplantation Outcomes and Treatments
- Spectroscopy and Quantum Chemical Studies
- Acute Kidney Injury Research
Michigan Medicine
2021-2025
University of Michigan–Ann Arbor
2009-2021
Ann Arbor Center for Independent Living
2015
National Institutes of Health
2015
Columbia University
2015
C. S. Mott Children's Hospital
2009-2014
University of California, Davis
2012
Purdue University West Lafayette
2008
Vanderbilt University
2006
Nitric oxide-releasing catheters, prepared with <italic>S</italic>-nitroso-<italic>N</italic>-acetylpenicillamine doped polymers, reduce thrombus and bacterial adhesion in a 7 day sheep model.
Abstract Acute kidney injury (AKI) is one of the most common complications liver transplantation (LT). We examined impact intraoperative management on risk for AKI following LT. In this retrospective observational study, we linked data from electronic health record with standardized transplant outcomes. Our primary outcome was stage 2 or 3 as defined by Kidney Disease Improving Global Outcomes guidelines within first 7 days used logistic regression models to test hypothesis that addition...
Chronic obstructive pulmonary disease (COPD) kills approximately 2.8 million people each year, and more than 80% of COPD cases can be attributed to smoking. Leukocytes recruited the lung contribute pathology by releasing reactive oxygen metabolites proteolytic enzymes. In this work, we investigated where leukocytes enter in early stages order better understand their effect as a contributor development COPD. We simultaneously evaluated parenchyma airways for neutrophil accumulation, well...
Uniaxial systems represent the next lowest symmetry below isotropic and are ubiquitous. The objective of present work is to a systematic foundation for interpreting polarization-dependent four-wave mixing measurements oriented aligned assemblies. Orientational averages connecting molecular frame macroscopic in uniaxial assemblies were derived several common groups coherent anti-Stokes Raman spectroscopy (CARS) measurements, two-photon (CATS) probing electronic transitions, resonant...
To investigate the effects of combination extracorporeal cardiopulmonary resuscitation and thrombolytic therapy on recovery vital organ function after prolonged cardiac arrest.Laboratory investigation.University laboratory.Pigs.Animals underwent 30-minute untreated ventricular fibrillation arrest followed by for 6 hours. Animals were allocated into two experimental groups: t-extracorporeal (t-ECPR) group, which received streptokinase 1 million units, control (c-ECPR), did not receive...
Multifunction surveillance alerting systems have been found to be beneficial for the operating room and labor delivery. This paper describes a similar system developed in-hospital acute care environments, AlertWatch Acute Care (AWAC).A decision support has which extracts comprehensive electronic health record (EHR) data including live from physiologic monitors ventilators incorporates them into an integrated organ icon-based patient display. Live retrieved hospitals network are processed by...
A novel technique for fabricating silicon dioxide (SiO2) and carbide (SiC) nanostructures on SiC substrates is reported in this paper. The involves amorphization of crystalline at the nanoscale using a focused ion beam followed by selective thermal oxidation that results oxide due to enhanced rate amorphous SiC. Selective etching nanostructures. Nanostructures (SiO2 SiC) with minimum feature sizes ∼55 nm have been fabricated. Oxide nano-channels channel widths less than 20 are demonstrated....
An implantable pediatric artificial lung (PAL) may serve as a bridge to transplantation for children with end-stage failure (ESLF); however, an animal model of is needed evaluate the efficacy PAL before it can enter clinical trials. The objective this study was assess ligation right pulmonary artery (rPA) ESLF. Seven lambs weighing 20-30 kg underwent rPA and were recovered monitored up 4 days. Intraoperatively, significantly increased physiologic dead space fraction (Vd/Vt; baseline = 48.6 ±...
Abstract Background Severe hypocalcaemia is associated with increased transfusion in the trauma population. Furthermore, patients developing severe have higher mortality and coagulopathy. Electrolyte abnormalities massive been less studied surgical Here, we tested primary hypothesis that volume of packed red blood cells fresh frozen plasma transfused intraoperatively lower nadir ionised calcium population receiving resuscitation. Methods We performed a retrospective observational study at an...
Weaning parameters are well studied in patients undergoing first time extubation. Fewer data exists to guide re-extubation of who failed their extubation attempt. It is reasonable postulate that improved weaning between the and second attempt would lead rates success. To investigate, we a cohort underwent at We hypothesized improvement associated with successful reextubation.Rapid shallow breathing index (RSBI), maximum inspiratory pressure (MIP), vital capacity (VC), blood partial CO2...
Introduction: Extracorporeal cardiopulmonary resuscitation (ECPR) after prolonged cardiac arrest (CA) often fails to restore and cerebral function. The primary limiting factor is presumed be ischemia duration. An alternative hypothesis that intravascular coagulation prevents tissue reperfusion. Hypothesis: Adding thrombolytics ECPR untreated CA improves recovery when compared alone. Methods: We developed a porcine model of 30 minute ventricular fibrillation followed by for 6 hours. Animals...
Trivedi, Suraj; Davis, Ryan; Engoren, Milo; Lorenzo, Javier; Jewell, Elizabeth; Maile, Michael Author Information