- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Radiation Effects in Electronics
- Nuclear Physics and Applications
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Glioma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Boron Compounds in Chemistry
- Sarcoma Diagnosis and Treatment
- Particle accelerators and beam dynamics
- Radiation Effects and Dosimetry
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Bone Tumor Diagnosis and Treatments
- Medical Image Segmentation Techniques
- Muscle activation and electromyography studies
- Effects of Radiation Exposure
- Motor Control and Adaptation
- Advanced MRI Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- Metallurgical Processes and Thermodynamics
- Advances in Oncology and Radiotherapy
Karl Landsteiner University of Health Sciences
2022-2025
MedAustron
2016-2025
University of Central Florida
2022-2025
American Physical Therapy Association
2022
Ludwig-Maximilians-Universität München
2020
Universitätsklinik für Strahlentherapie
2020
University of Vienna
2020
Medical University of Vienna
2008-2017
Bellingham Technical College
2017
Vienna General Hospital
2011-2013
A holographic 3D display with 300 mm×200 mm active area was built. The includes a spatial light modulator that modulates amplitude and phase of thus enables reconstruction high efficiency. Furthermore, optical elements in photopolymer films laser sources are used. requirements on these components discussed. Photographs taken at the demonstrate scene is reconstructed depth, enabling selective accommodation observer's eye lenses natural depth perception. results advantages SeeReal's solution.
•Improvement of therapeutic ratio by novel unconventional radiotherapy approaches.•Immunomodulation using high-dose spatially fractionated radiotherapy.•Boosting radiation anti-tumor effects adding an immune-mediated cell killing.
Abstract Purpose Carbon ion radiotherapy (CIRT) relies on relative biological effectiveness (RBE)‐weighted dose calculations. Japanese clinics predominantly use the microdosimetric kinetic model (MKM), while European centers utilize local effect (LEM). Despite both models estimating RBE‐distributions in tissue, their physical and mathematical assumptions differ, leading to significant disparities RBE‐weighted doses. Several adopted treatment schedules, necessitating adjustments prescriptions...
In IMRT, the method for a quantitative comparison of two-dimensional dose distributions is still under development. The gamma evaluation proposed by Low et al most accepted approach and has been adapted many groups. Based on concept we developed software tool with an intelligent search algorithm to minimize calculation time. For interpretation deviations y angle distribution other tools (dose difference map, profiles, area histograms, etc) are integrated in package. Ten hybrid plans included...
In this paper, we investigate the possibility to use X-ray based real time 2D/3D registration for non-invasive tumor motion monitoring during radiotherapy.The scheme is implemented using general purpose computation on graphics hardware (GPGPU) programming techniques and several algorithmic refinements in process. Validation conducted off-line a phantom five clinical patient data sets. The performed region of interest (ROI) centered around planned target volume (PTV).The measured with an rms...
<h2>Abstract</h2><h3>Introduction</h3> : Intracerebral radiation-induced contrast enhancement (RICE) can occur after photon as well proton beam therapy (PBT). This study evaluated the incidence, characteristics and risk factors of RICE PBT delivered to, or in direct proximity brain its impact on health-related quality life (HRQoL). <h3>Material Method</h3> Four hundred twenty-one patients treated by pencil beam-scanning between 2017 2021 were included. Follow-up included clinical evaluation...
Respiration can cause tumor movements in thoracic regions of up to . To minimize motion effects several approaches, such as gating and deep inspiration breath hold (DIBH), are still under development. The goal our study was develop evaluate a noninvasive system for gated DIBH (GDIBH) based on external markers. monitoring an infrared tracking in-house-developed software. in-house software provided the breathing curve real time used on-line information prototype feedback device....
The dose core of a proton pencil beam (PB) is enveloped by low area reaching several centimeters off the central axis and containing considerable amount dose. Adequate modeling different components PB profile is, therefore, required for accurate calculation. In this study, we experimentally validated one electromagnetic two nuclear scattering models in GATE/Geant4 calculation beams therapeutic energy window (62-252 MeV) with without range shifter (RaShi).The multiple Coulomb (MCS) model was...
Head and neck mucosal melanomas (HNMMs) are aggressive, radiotherapy-resistant cancers. Previous JCROS studies demonstrated improved local control with carbon-ion radiotherapy (CIRT). This study evaluates early outcomes of CIRT for HNMM using the European Japanese relative biological effectiveness (RBE)-adapted dose prescriptions. Between November 2019 April 2023, 14 patients received treatment. Postoperative R2 resection: 9 cases; biopsies only: 5 cases. Immune checkpoint inhibitors used as...
Purpose: In this article, the authors propose a new gold standard data set for validation of two‐dimensional/three‐dimensional (2D/3D) and 3D/3D image registration algorithms. Methods: A was produced using fresh cadaver pig head with attached fiducial markers. The used several imaging modalities common in diagnostic or radiotherapy, which include 64‐slice computed tomography (CT), magnetic resonance Tl, T2, proton density sequences, cone beam CT data. Radiographic were acquired kilovoltage...
Anatomical changes in the head-and-neck (H&N) region during course of treatment can cause deteriorated dose distributions. Different replanning strategies were investigated for volumetric modulated arc therapy (VMAT) and intensity-modulated proton (IMPT).