A5069198911- Fibroblast Growth Factor Research
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Dendrimers and Hyperbranched Polymers
- Electrospun Nanofibers in Biomedical Applications
- Plasma Applications and Diagnostics
- Radiopharmaceutical Chemistry and Applications
- Angiogenesis and VEGF in Cancer
- Extracellular vesicles in disease
- Autophagy in Disease and Therapy
- Hematological disorders and diagnostics
- Acute Myeloid Leukemia Research
- Hippo pathway signaling and YAP/TAZ
Peking University Shenzhen Hospital
2021
University of Hong Kong - Shenzhen Hospital
2021
Qilu Hospital of Shandong University
2010
Establishment of functional and stable collaterals in the ischemic myocardium is crucial to restoring cardiac function after myocardial infarction. Here, we show that only dual delivery a combination angiogenic arteriogenic factors could significantly reestablish collateral networks improve perfusion function. A FGF-2 with PDGF-BB, two primarily targeting endothelial cells vascular smooth muscle cells, remarkably promotes growth stabilizes newly formed networks, which restore Using various...
Aim: This work aims to develop an injectable nano-drug delivery system overcome tumor multidrug resistance (MDR). Methods: A drug nanoplatform based on PEGylated PLGA with glutathione (GSH) responsivity was constructed for dual of doxorubicin and curcumin (termed DCNP), its MDR reversal efficiency studied in vitro vivo. Results: The DCNPs exhibited a rapid release profile under high GSH concentration could enhance the cellular uptake cytotoxicity cancer cells. Moreover, showed better...
Abstract Many studies have shown, using two‐dimensional culture, that low‐temperature plasma‐jet‐activated medium (PAM) inhibits the growth of various tumor cells, whereas its effects and mechanisms in three‐dimensional (3D) culture system remain unclear. In this study, a 3D cell model was used to study inhibition tumorigenesis PAM vitro. Our results showed significantly suppressed spheroid formation downregulated stemness‐related genes A549 cells “before,” “during,” “after” sphere...