A5055065304- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Esophageal and GI Pathology
- Organ Transplantation Techniques and Outcomes
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- COVID-19 epidemiological studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Tracheal and airway disorders
- Nutrition and Health in Aging
- Angiogenesis and VEGF in Cancer
- Diagnosis and treatment of tuberculosis
- Clinical Nutrition and Gastroenterology
- Dermatological and COVID-19 studies
- Hepatitis C virus research
- Esophageal Cancer Research and Treatment
- Gastrointestinal disorders and treatments
- Infective Endocarditis Diagnosis and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- COVID-19 Pandemic Impacts
- Dysphagia Assessment and Management
- Foreign Body Medical Cases
- Cardiac Valve Diseases and Treatments
Maulana Azad Medical College
2023-2024
Govind Ballabh Pant Hospital
2015-2024
Medanta The Medicity
2023
Centre for Development of Advanced Computing
2020-2021
Institute of Post Graduate Medical Education and Research
2016-2019
Institute of Medical Sciences
2016
All India Institute of Medical Sciences
1989-2015
Indian Veterinary Research Institute
2015
James Cook University Hospital
2011
Birla Institute of Technology and Science, Pilani
2010
Hepatic encephalopathy (HE) is associated with poor prognosis in cirrhosis. Drugs used the treatment of HE are primarily directed at reduction blood ammonia levels. Rifaximin and lactulose have shown to be effective HE. We evaluated efficacy safety rifaximin plus vs. alone for overt HE.In this prospective double-blind randomized controlled trial, 120 patients were into two groups: (group A 1,200 mg/day; n=63) group B (lactulose (n=57) placebo). The primary end point was complete reversal...
Malnutrition is frequent in patients with cirrhosis and associated complications like ascites, hepatic encephalopathy, infections, death. We determined the prevalence of malnutrition by various methods its clinical importance cirrhosis.Consecutive from August 2013 to February 2015 were assessed. Nutritional status was assessed traditional model (mid-arm circumference, triceps skinfold thickness, serum albumin, creatinine height index, total lymphocyte count), handgrip, body composition...
Abstract Background and Aims Data on the use of intravenous L‐ornithine L‐aspartate (LOLA) in treatment overt HE (OHE) is limited. We evaluated role LOLA patients cirrhosis with OHE grade III–IV. Approach Results In a double‐blind randomized placebo‐controlled trial, 140 were to combination LOLA, lactulose, rifaximin ( n = 70) or placebo, 70). was given as continuous infusion at dose 30 g over 24 h for 5 days. Ammonia levels, TNF‐α, ILs, endotoxins measured days 0 5. The primary outcome...
Abstract Background Hepatic encephalopathy (HE) is associated with poor prognosis and treatment of HE primarily directed at the reduction blood ammonia levels. The study evaluated efficacy safety albumin plus lactulose versus alone for overt HE. Methods In prospective randomized controlled trial, 120 patients were in two groups: group A ( n = 60) B 60). Primary end point was complete reversal HE, secondary points mortality hospital stay. Results total (mean age 40.4 ± 9.3 years) included...
To study the role of probiotics on gut permeability and endotoxemia in patients with acute pancreatitis (AP).Bacterial translocation has been implicated infective complications AP, which shown to be prevented by probiotics.A double-blind, randomized placebo-controlled trial was conducted. Consecutive AP presenting within 72 hours after onset abdominal pain or who had nil orally at time presentation for up 5 days were included study. The probiotic group received 4 sachets Probiotics (2.5...
Minimal hepatic encephalopathy (MHE) represents the mildest form of (HE), with abnormal neuropsychologic findings. Inflammatory response may be important in pathogenesis MHE. On magnetic resonance spectroscopy (MRS), improvement metabolic ratios after liver transplantation suggests an role myoinositol (mI) and choline (cho) development MHE.To investigate arterial ammonia, tumor necrosis factor alpha (TNF-α), interleukin (IL)-6, IL-18, serum endotoxin, MRS before treatment MHE.Sixty patients...
Hepatic encephalopathy (HE) is associated with a poor prognosis. There no study on the prevention of recurrence L-ornithine L-aspartate (LOLA).We conducted double-blind randomized controlled trial at tertiary center. Consecutive patients cirrhosis who had recovered from HE were to receive LOLA (6 g thrice daily) or similar amount placebo by computer-based randomization for 6 months. Patients assessed psychometric scores using five paper-pencil tests, critical flicker frequency test, arterial...
Background and Aim Esophageal involvement in tuberculosis (TB) is rare usually secondary. Data on esophageal TB are scarce. We aimed to analyze clinical endoscopic features outcomes of treatment TB. Methods retrospectively identified patients with from January 2014 December 2016 at GB Pant Hospital. Well‐defined granuloma or without caseation and/or acid‐fast bacilli staining either biopsy the adjacent mediastinal lymph node fine‐needle aspiration cytology (FNAC) specimen, along response...
To investigate the role of recombinant human interleukin-11 (rhIL-11) on in vivo mobilization CD34(+)/vascular endothelial growth factor receptor (VEGFR) 2(+) mononuclear cells and collateral vessel remodeling a mouse model hindlimb ischemia.We observed that treatment Sv129 mice with continuous infusion 200-μg/kg rhIL-11 per day led to CD34(+)/VEGFR2(+) peaked at 72 hours. pretreated for hours before femoral artery ligation showed 3-fold increase plantar perfusion, leading faster blood flow...
Studies comparing surgical versus endoscopic drainage of pseudocyst customarily include patients with both acute and chronic pseudocysts the modalities used for are protean. We compared outcomes following cystogastrostomy (ECG) (SCG) in pseudocyst.Seventy-three requiring from 2011 to 2014 were analysed (18 excluded: transpapillary n = 15; cystojejunostomy 3). The remaining 55 divided into two groups, ECG 35 SCG 20, their (technical success, successful drainage, complication rate hospital...
In a country like India, where the prevalence of tuberculosis is very high, role screening tools for detection latent infection (LTBI) TST and IGRA still unclear, especially in inflammatory bowel disease (IBD) patients. Our study aimed at comparing interferon-gamma release assay (IGRA) tuberculin skin test (TST) to determine LTBI IBD patients Indian subset population.It was prospective observational analysis. A total 257 participants were included study. Both performed consecutive diagnosed...
Minimal hepatic encephalopathy (MHE) represents the mildest form of encephalopathy. Spectral electroencephalogram (sEEG) analysis improves recognition MHE by decreasing inter-operator variability and providing quantitative parameters brain dysfunction. We compared sEEG in patients with cirrhosis without effects lactulose on MHE.One hundred (50 50 MHE) were enrolled. Diagnosis was based psychometric score (PHES) ≤ -5. Critical flicker frequency, model end-stage liver disease score, performed...
<b>Background and aims</b> Perforation is one of the worst complications therapeutic endoscopic retrograde cholangiopancreatography (ERCP). We aimed to study epidemiology ERCP related perforation impact completion intended procedure on outcome this complication. <b>Methods</b> records from January 2007 April 2012 were independently evaluated by two investigators for occurrence perforations. A total 11 500 patients underwent during period. The case 171 (1.5 %) with perforations reviewed...