- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Gallbladder and Bile Duct Disorders
- Cancer Research and Treatments
- Ferroptosis and cancer prognosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Cancer, Lipids, and Metabolism
- PI3K/AKT/mTOR signaling in cancer
- Cancer-related molecular mechanisms research
- Esophageal and GI Pathology
- Biosimilars and Bioanalytical Methods
- Chemical Synthesis and Analysis
- Viral-associated cancers and disorders
- Inflammatory Biomarkers in Disease Prognosis
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Marine Toxins and Detection Methods
- Viral Infections and Outbreaks Research
- Cancer Mechanisms and Therapy
- Neurofibromatosis and Schwannoma Cases
- Medical Research and Treatments
- Vaccine Coverage and Hesitancy
The Affiliated Yongchuan Hospital of Chongqing Medical University
2011-2023
Chongqing Medical University
2011-2023
Second People’s Hospital of Yibin
2010
Chongqing University
2009
Pancreatic adenocarcinoma (PAAD) is a disease with atypical symptoms, an unfavorable response to therapy, and poor outcome. Abnormal guanylate-binding proteins (GBPs) play important role in the host's defense against viral infection may be related carcinogenesis. In this study, we sought determine relationship between GBP2 expression phenotype patients PAAD explored possible underlying biological mechanism.We analyzed of tissues using multiple gene database cohort 42 patients. We evaluated...
Abstract Purpose: To identify differentially expressed immune-related genes (DEIRGs) and construct a model with survival-related DEIRGs for evaluating the prognosis of patients pancreatic cancer (PC). Methods: Six microarray gene expression datasets PC from Gene Expression Omnibus (GEO) Immunology Database Analysis Portal (ImmPort) were used to DEIRGs. RNA sequencing clinical data The Cancer Genome Atlas Program-Pancreatic Adenocarcinoma (TCGA-PAAD) database establish prognostic model....
Hepatic and coagulation function are routine laboratory tests prior to curative hepatectomy. The prognostic value of gamma-glutamyl transpeptidase (GGT) platelet ratio (GPR) international normalized (INR) in surgically treated patients with intrahepatic cholangiocarcinoma (ICC) remains unclear. ICC received hepatectomy two west China centers were included. Time-dependent ROC curves conducted compare established indexes for ICC. GPR-INR score was introduced evaluated using the AUC curve...
Laparoscopic pancreaticoduodenectomy (LPD) is widely used as a treatment for periampullary tumors and pancreatic head tumors. However, postoperative fistula (POPF), which significantly affects mortality length of hospital stay patients, remains one the most common serious complications following LPD. Though numerous technical modifications pancreaticojejunostomy (PJ) have been proposed, POPF still "Achilles heel" LPD.To reduce rate other LPD by exploring best approach to manage with remnant,...
A 64-year-old woman with a history of recurrent acute pancreatitis was referred for treatment intraductal papillary mucinous neoplasia (IPMN) that found during computed tomography (CT) scan in local hospital. Magnetic resonance cholangiography (MRCP) presented dilation the main pancreatic duct and suspicious nodules ([Fig. 1]). Endoscopic retrograde cholangiopancreatography (ERCP) showed significantly dilatated there seemed to be cystic lesion at head pancreas 2]). Further evaluation digital...
Background: There are currently no recognised biomarkers that identify predictive groups of benefit in patients with hepatocellular carcinoma receiving immune-combined targeted therapy, for which we explored the value peripheral blood markers as their prognosis. Methods: Patients who underwent anti-PD-1 combination therapy from 1 January 2019 to 31 December 2021 at First Affiliated Hospital Chongqing Medical University were retrospectively analysed. The data collected analysed by R software....
Objective: To explore the application of indocyanine green fluorescence navigation in open cholecystectomy. Methods: Forty-eight patients with extrahepatic cholangiography who underwent cholecystectomy our hospital from March 2016 to February 2018 were enrolled. They divided into control group (24 cases) and experimental by using random number table method. The was treated conventional X-ray cholangiopancreatography, near-infrared imaging for cholangiography. success rate, time, economic...
Objective To study the association between ratio of peritumoral hepatic stellate cells to γδ T (SGR) and prognosis patients with hepatocellular carcinoma (HCC) after curative resection. Methods From January 2011 December 2013, clinical data 320 HCC who underwent resection at Department Hepatobiliary Surgery, First Affiliated Hospital Chongqing Medical University were collected analyzed retrospectively. Immunohistochemistry was used calculate SGR in adjacent cancer tissues. Survival...