- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Cardiac Valve Diseases and Treatments
- Simulation-Based Education in Healthcare
- Cardiovascular Function and Risk Factors
- Lymphoma Diagnosis and Treatment
- Health and Well-being Studies
- Lung Cancer Treatments and Mutations
- Occupational and environmental lung diseases
- Pain Mechanisms and Treatments
- T-cell and B-cell Immunology
- Colorectal Cancer Treatments and Studies
- Cytomegalovirus and herpesvirus research
- Infective Endocarditis Diagnosis and Management
- Cancer Treatment and Pharmacology
- Pleural and Pulmonary Diseases
- Botulinum Toxin and Related Neurological Disorders
- Chemokine receptors and signaling
- Cancer Research and Treatments
- Cancer-related molecular mechanisms research
- Advanced Breast Cancer Therapies
- Nursing Roles and Practices
- Cardiovascular and exercise physiology
- Vascular Tumors and Angiosarcomas
- Viral-associated cancers and disorders
West China Hospital of Sichuan University
2009-2024
Sichuan University
2010-2024
People's Liberation Army 401 Hospital
2024
The First People's Hospital of Changzhou
2024
Abstract: Renal hemangioblastoma (HB) is a rare subset of HBs arising outside the central nervous system (CNS), with its molecular drivers remaining entirely unknown. There were no significant alterations detected in previous studies, including von Hippel-Lindau gene alterations, which are commonly associated CNS-HB. This study aimed to determine real identity renal HB and better understand relationship A cohort 10 was submitted for next-generation sequencing technology. As control, 5...
The purpose of this study was to investigate whether hemoglobin-based oxygen carrier (HBOC) could protect the heart from intense exercise-induced myocardial dysfunction. Adult male Sprague-Dawley rats were subjected 5-h prolonged running on treadmill with or without HBOC pre-treatment. Immediately after exercise, rate (HR) and delivery capacity blood measured. After 1 h rest, echocardiography performed assess post-exercise cardiac function. Then all hearts isolated perfused using Langendorff...
Introduction Acute lymphoblastic leukaemia/lymphoma ( ALL / LBL ) is an aggressive entity of precursor lymphoid neoplasm and may cause malignant serous effusion SE ). The current study aimed to analyse the characteristics cytology including cytomorphology, immunophenotyping, clonality evaluate effectiveness as a diagnostic method for . Methods specimens with final diagnosis from 2006 2016 were reviewed clinical data, cytomorphological features ancillary studies. Cytodiagnoses compared...
To examine the association of handgrip strength with aortic stenosis incidence among adults aged 60 years and older. We conducted a cohort study using UK Biobank data to assess relationship between incident in individuals Handgrip was measured Jamar J00105 hydraulic hand dynamometer. Adjusted Cox proportional hazards regression models were stenosis. included 157,097 participants (78,151 women 78,946 men) our study, mean age 64 ± 2.9 years. During median follow-up 8.1 (7.4-8.8) years, 1543...
Background: EGFR-TKI has become the standard-of-care therapy for advanced NSCLC harbouring EGFR mutation. However, efficacy varies widely, suggestive of other confounding factors. Obesity is related to etiology, morbidity, and mortality cancer. its impact on remains unknown. Methods: This was a multi-center, real-world study conducted in 3 tertiary referring medical centers. Treatment-naive metastatic patients mutation who were prescribed with TKI (gefitinib, erlotinib, or icotinib)...
Introduction Major depressive disorder (MDD) is characterized by both clinical symptoms and cognitive deficits. Prior studies have typically examined either or cognition correlated with brain measures, thus causing a notable paucity of stable markers that capture the full characteristics MDD. Brain controllability derived from newly proposed model integrating metabolism (energy cost) dynamics control perspective has been considered as sensitive biomarker for characterizing function. Thus,...
There may be significant histopathological overlap between Epstein–Barr virus (EBV) -positive diffuse large B cell lymphoma (DLBCL) and other diagnoses, including angioimmunoblastic T-cell (AITL). Herein, we report a rare case of EBV-positive AITL developing two years after the initial diagnosis DLBCL. Histone deacetylase (HDAC) inhibitor, chidamide, in combination with COEP (cyclophosphamide, vindesine, etoposide, prednisone) were administrated to treat AITL, which appeared prolong survival...
Introduction There is a growing consensus on brain networks that it not immutable but rather dynamic complex system for adapting environment. The neuroimaging research studying how regions work collaboratively with methods had demonstrated its effectiveness in revealing the neural mechanisms of schizophrenia. Objectives To investigate altered functional topology first-episode untreated schizophrenia patients (SZs) and establish classification models to find objective imaging biomarkers....
Introduction Apart from the psychiatric symptoms, cognitive deficits are also core symptoms of schizophrenia. Brain network control theory provided information on role a specific brain region in process, helping understand neural mechanism impairment Objectives To characterize properties functional first-episode untreated patients with schizophrenia and relationships between controllability as well exploring predictive value differentiating healthy controls (HCs). Methods Average modal...