A5077515897- Thyroid Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Genetic factors in colorectal cancer
- Head and Neck Anomalies
- Intraperitoneal and Appendiceal Malignancies
- Glioma Diagnosis and Treatment
- Amoebic Infections and Treatments
- Pituitary Gland Disorders and Treatments
- Congenital Anomalies and Fetal Surgery
- Ovarian cancer diagnosis and treatment
- Parasitic infections in humans and animals
- Tuberous Sclerosis Complex Research
- Tumors and Oncological Cases
- Adrenal and Paraganglionic Tumors
- Hepatocellular Carcinoma Treatment and Prognosis
- Fungal Infections and Studies
- Neuroendocrine Tumor Research Advances
- Vascular Tumors and Angiosarcomas
- Hernia repair and management
- Ultrasound and Hyperthermia Applications
- Infectious Diseases and Mycology
- BRCA gene mutations in cancer
- Appendicitis Diagnosis and Management
- Antifungal resistance and susceptibility
- Salivary Gland Tumors Diagnosis and Treatment
Wuhan University
2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024
Wenzhou Medical University
2024
Sichuan University
2014-2023
West China Hospital of Sichuan University
2014-2023
BACKGROUND Surgical resections or tumor biopsies are often not available for patients with late‐stage non‐small cell lung cancer (NSCLC). Cytological specimens, such as malignant pleural effusion (MPE) blocks, critical molecular testing. Currently, diagnostic methods to identify anaplastic lymphoma kinase ( ALK ) rearrangements include fluorescence in situ hybridization (FISH), real‐time reverse transcriptase‐polymerase chain reaction (RT‐PCR), and immunohistochemistry (IHC). In the current...
Abstract Background Anaplastic thyroid cancer (ATC) is a rare but lethal malignancy, and few systematic investigations on genomic profiles of ATC have been performed in Chinese patients. Methods Fifty-four patients West China Hospital between 2010 to 2020 were retrospectively analyzed, while 29 with available samples sequenced by whole-exome sequencing (WES). The associations alterations clinical characteristics statistically evaluated. Results median overall survival was 3.0 months the...
Currently, 5 scoring systems have been proposed in the literature for predicting metastatic risk pheochromocytoma and paraganglioma (PPGL): Pheochromocytoma of Adrenal Gland Scaled Score (PASS), Grading System Paraganglioma (GAPP), Composite Pheochromocytoma/paraganglioma Prognostic (COPPS), Age, Size, Extra-adrenal location, Secretion type (ASES) score, Genetic, PASS (SGAP) model. To validate evaluate these systems, we conducted a retrospective review cases diagnosed as PPGL at Department...
Ischemic stroke is one of the leading causes chronic disability worldwide, and stroke-induced heart damage can lead to death. According research, patients with a variety brain disease have good clinical results after vagus nerve stimulation (VNS). After ischemic stroke, mast cells (MCs) degranulate release large number mediators, which may cause systemic inflammation. Chymase secreted by MCs increase levels pathological angiotensin II (AngⅡ), plays crucial role in deterioration disease. Our...
Kaposi's sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus that encodes numerous cellular homologs, including cyclin D, G protein-coupled protein, interleukin-6, and macrophage inflammatory proteins 1 2. KSHV vCyclin encoded by ORF72, the homolog of cyclinD2. can regulate replication cell proliferation constitutively activating cyclin-dependent kinase 6 (CDK6). However, regulatory mechanism has not been fully elucidated. In present study, we identified host protein named...
Abstract Aims The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has been widely adopted since its introduction. In this study, we aimed to report our experience using reporting system at a College of American Pathologists (CAP)‐accredited hospital laboratory in large series Chinese patients. Methods All patients who underwent preoperative ultrasound‐guided thyroid fine‐needle aspiration (FNA) from January 2011 August 2016 were retrospectively analyzed. FNAs classified...
Hepatic echinococcosis (HE) is a zoonotic disease caused by Echinococcus, and Echinococcus granulosus E. multilocularis are the most common, causing cystic (CE) alveolar (AE), respectively. Contrast-enhanced ultrasound (CEUS) an imaging technique which has been recommended for identifying focal lesions in liver. However, effect of CEUS on differentiation hepatic type remains unclear.Twenty-five patients with 46 HE confirmed histopathology our hospital from December 2019 to May 2022 were...
Abstract Background Splenogonadal fusion (SGF) is a rare congenital malformation that occurs during embryonic development. SGF typically presents as left-sided scrotal swelling, left inguinal hernia, mass, or cryptorchidism. Therefore, it easily misdiagnosed, and unnecessary orchiectomy may occur. This study aimed to report case of SGF. Case presentation A 5-month-old male child presented with history obvious swelling for 1 month, which progressively worsened 10 h before the hospital visit....
Conventional cytopathology examination of respiratory samples can aid in identifying Aspergillus but with poor sensitivity, so this study aimed to assess the potential liquid-based test (LCT) for improving identification following Papanicolaou's or Special staining Grocott's methenamine silver periodic acid-Schiff staining. Paired bronchial brushing (n = 54) and sputum 117) from 171 patients pulmonary aspergillosis were prepared as slides using either conventional SurePath LCT. LCT generally...
Objective: Thyroid nodules are highly prevalent and a common clinical problem worldwide. How to identify the nature of nodule is major concern clinicians. Fine needle aspiration cytology (FNAC) has an established role well-utilized in management. However, unsatisfactory nondiagnostic indeterminate rates limit its usage lead some unnecessary surgery. Hashimoto thyroiditis (HT) prevalently found concurrent with thyroid nodules. Whether HT can influence accuracy cytopathological diagnosis still...
Introduction Acute lymphoblastic leukaemia/lymphoma ( ALL / LBL ) is an aggressive entity of precursor lymphoid neoplasm and may cause malignant serous effusion SE ). The current study aimed to analyse the characteristics cytology including cytomorphology, immunophenotyping, clonality evaluate effectiveness as a diagnostic method for . Methods specimens with final diagnosis from 2006 2016 were reviewed clinical data, cytomorphological features ancillary studies. Cytodiagnoses compared...
Background: Pulmonary mucormycosis, a relatively rare but severe pulmonary fungal disease with high mortality rate, is difficult to diagnose in immunocompromised patients. Conventional cytopathology (CCP) examination of respiratory samples can help detect Mucorales, its diagnostic sensitivity poor. The aim this study was assess the first application liquid-based test (LCT) Mucorales. Methods: A total 33 pairs bronchial brushing from 27 patients diagnosed as mucormycosis by fiberoptic...
Distant metastases are more common in follicular thyroid carcinoma (FC) than papillary carcinoma. However, FC metastasis to the kidney with eggshell calcification, as observed present case, is rare. The current report presents a case of 67-year-old woman exhibiting solitary tumor mid pole left kidney. Radical nephrectomy was performed, diagnosed primary renal using contrast-enhanced computed tomography. Once confirmed be FC, total thyroidectomy performed. Following administration an oral...