Zhiyong Shen

ORCID: 0000-0001-7629-0743
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • HIV Research and Treatment
  • Adolescent Sexual and Reproductive Health
  • Sex work and related issues
  • HIV/AIDS drug development and treatment
  • HIV-related health complications and treatments
  • Sexuality, Behavior, and Technology
  • Dermatology and Skin Diseases
  • Mental Health Treatment and Access
  • LGBTQ Health, Identity, and Policy
  • COVID-19 and Mental Health
  • Skin Protection and Aging
  • Indoor Air Quality and Microbial Exposure
  • Hepatitis C virus research
  • HIV, TB, and STIs Epidemiology
  • Stress Responses and Cortisol
  • Healthcare professionals’ stress and burnout
  • Maternal Mental Health During Pregnancy and Postpartum
  • Sexual function and dysfunction studies
  • Mobile Health and mHealth Applications
  • Employment and Welfare Studies
  • Poverty, Education, and Child Welfare
  • Immune Cell Function and Interaction
  • Health disparities and outcomes

Guangxi Center for Disease Prevention and Control
2015-2024

The People's Hospital Tongling
2024

Yangzhou University
2024

China Energy Science and Technology Research Institute Co., Ltd. (China)
2024

Shenzhen Institutes of Advanced Technology
2024

Soochow University
2023

Children's Hospital of Suzhou University
2023

City University of Hong Kong
2023

Guiyang Medical University
2023

University of South Carolina
2019-2022

This study aimed to investigate the prevalence of HIV late presentation and advanced disease identify factors associated with among patients newly diagnosed HIV/AIDS in Guangxi Zhuang Autonomous Region, Southwestern China.Patients registered surveillance system Centers for Disease Control between January 2012 December 2016 were included this study.Of 45,118 patients, 70.2% had presentation, 45.1% disease. A higher was found male heterosexuals female people who use drugs (PWID). Heterosexuals...

10.1186/s12981-019-0221-7 article EN cc-by AIDS Research and Therapy 2019-03-16

Background Multistage stepwise HIV testing and treatment initiation procedures can result in lost opportunities to provide timely antiretroviral therapy (ART). Incomplete patient engagement along the continuum of care translates into high levels preventable mortality. We aimed evaluate ability a simplified test treat structural intervention reduce Methods Findings In "pre-intervention 2010" (from January 2010 December 2010) 2011" 2011 2011) phases, patients who screened HIV-positive at...

10.1371/journal.pmed.1001874 article EN cc-by PLoS Medicine 2015-09-08

The existing literature suggests a negative impact of intersectional stigma on multiple aspects psychosocial well-being among individuals with stigmatized identities. However, such remains poorly understood. This study aims to investigate the association between and 193 men who have sex (MSM) living HIV. Based their responses measures HIV-related sexual gender minority (SGM) stigma, participants were grouped into "high" vs "low" each type stigma. General Linear Model (GLM) was used analyze...

10.1080/09540121.2020.1739205 article EN AIDS Care 2020-03-10

Men who have sex with men (MSM) represent the fastest growing key population for incident HIV cases in China. We examined five consecutive years of and syphilis prevalence risk factors data among MSM Guangxi Province second highest estimated number people living HIV/AIDS (PLWHAs) China 2011. collected demographic behavioral from national sentinel surveillance HIV/syphilis blood samples annual cross-sectional surveys 2008 to 2012. analyzed trends stratified by social/behavioral...

10.1186/1471-2334-14-367 article EN cc-by BMC Infectious Diseases 2014-07-03

Introduction Female sex workers (FSWs) are at highest risk for contracting HIV and facilitating the current heterosexual epidemic in Guangxi, China, yet little is known of impact recent harm reduction campaigns province. We analyzed sentinel surveillance data collected between 2010 2012 Guangxi to explore correlations prevalence HIV, hepatitis C (HCV), syphilis behaviors different categories FSWs Guangxi. Methods The 5,1790 all 14 prefectures 64 city/county regions China from were collected....

10.1371/journal.pone.0115311 article EN public-domain PLoS ONE 2015-02-27

Numerous researches have shown pernicious effects of stigma against people living with HIV/AIDS (PLWHA). However, no available studies reported these negative including emotional, physical to financial burdens PLWHA. In the current study, we aim explore different types (e.g., perceived, internalized and enacted) relevant consequences among PLWHA in China. A cross-sectional study was conducted from 2012 2013 Guangxi Autonomous Region The validated Berger HIV Stigma Scale used measure various...

10.1080/09540121.2016.1146206 article EN cc-by-nc-nd AIDS Care 2016-02-17

In the current study, we tested hypothesis that people who contracted HIV from "blameless" routes (e.g., blood transfusion, sex with stable partners) are less stigmatized compared to "blamable" injection drug use, workers). A cross-sectional study was conducted among 2,987 participants in Guangxi province, China, between 2012 and 2013. We employed both explanatory predictive modeling strategy by using multivariate linear regression models. models, assessed association of infection three...

10.1371/journal.pone.0151078 article EN cc-by PLoS ONE 2016-03-16

HIV healthcare providers might be vulnerable to mental health problems during the COVID-19 pandemic. Guided by stress and coping paradigm, current study aimed at examining interactive effects of COVID-19-related stressors on problems. A cross-sectional online survey was conducted among 1029 in Guangxi, China. The prevalence depression anxiety 13.31% 6.61%, respectively. Results from path analyses revealed that main were significant both anxiety. interaction had Simple slope tests more...

10.1007/s10461-020-03073-z article EN other-oa AIDS and Behavior 2020-10-30

Abstract Background The widespread use of antiretroviral therapy (ART) has resulted in the development transmitted drug resistance (TDR), which reduces ART efficacy. We explored TDR prevalence and its associated risk factors newly diagnosed individuals Guangxi. Methods enrolled 1324 participants who were with HIV-1 had not received at voluntary counselling testing centres (VCT) Guangxi, China, ART. Phylogenetic relationship, transmission cluster, genotypic analyses performed using pol...

10.1186/s12879-021-05854-w article EN cc-by BMC Infectious Diseases 2021-02-08

Abstract Current WHO guidelines recommend initiating ART regardless of CD4+ cell count. In response, we conducted an observational cohort study to assess the effects pre-ART count levels on death, attrition, and death or attrition in HIV treated patients. This large treatment (n = 49,155) from 2010 2015 was Guangxi, China. We used a Cox regression model analyze associations between counts attrition. The average mortality rates among all patients were 2.63 deaths 5.32 attritions per 100...

10.1038/s41598-017-03384-7 article EN cc-by Scientific Reports 2017-06-05

Clients of female sex workers (CFSWs) are a bridge population for the spread HIV and syphilis to low or average risk heterosexuals. Most studies have examined point prevalence these infections in CFSWs. Limited evidence suggests that older age CFSWs at higher acquiring sexually transmitted diseases compared with younger clients. Thus, we sought describe long-term trends HIV, syphilis, hepatitis C (HCV) better understand how differ by worker classification client age. We also HCV among...

10.1097/md.0000000000003726 article EN cc-by-nc Medicine 2016-05-01

Abstract Background Antiretroviral therapy (ART) has reduced mortality among people living with HIV (PLWH) in China, but co-infections of hepatitis B virus (HBV) and C (HCV) may individually or jointly reduce the effect ART. This study aimed to evaluate impacts HBV/HCV coinfections on treatment drop-out PLWH Methods A retrospective cohort analysis 58 239 who initiated antiretroviral during 2010–2018 was conducted Guangxi Province, China. Data were from observational database National Free...

10.1186/s40249-021-00921-5 article EN cc-by Infectious Diseases of Poverty 2022-01-06

Despite the vigorous global efforts to reduce stigma, HIV-related stigma continues undermine health status of people living with HIV (PLHIV). Internalized may cause stress adversely affecting PLHIV. Resilience is process an effective coping and positive adaption in face adversities. To date, limited data are available on mediating role resilience relationship internalized among PLHIV China. A cross-sectional survey was conducted 2987 Guangxi Autonomous Region (Guangxi) mediation analysis...

10.1080/09540121.2015.1054338 article EN AIDS Care 2015-08-14

This study collected data from 2987 people living with HIV in China and employed structural equation modeling to examine the relationships among social support, depression, quality of life (QOL). Depression was strongest predictor psychological, energy, mobility aspects QOL β = −.70 (p < .001), −.47 −.44 respectively. Emotional support a significant depression (β −.12, p .20, energy .15, psychological aspect .06, .05). Informational −.08, .01), −.06, .05), −.07, .001). Functional only...

10.1080/09540121.2016.1224298 article EN AIDS Care 2016-09-02

Heterosexual intercourse accounted for 93% of reported HIV cases in Guangxi, and Guangxi had 10% China's total number cases. Older men are particularly vulnerable to STIs, example, 46% Guangxi's were over 50 years age. As this is an under-studied population China, effective prevention control policies have yet be developed. Thus, the aim study was use a large-scale cross-sectional survey understand demographic behavior factors associated with syphilis infections among older male clients...

10.1186/s12879-017-2367-z article EN cc-by BMC Infectious Diseases 2017-04-11

HIV partner disclosure may facilitate social support, improve psychological well-being among HIV-infected individuals, and promote testing prevention their sexual partners. A growing literature emphasizes the critical role of interpersonal factors play in decision-making practice regarding disclosure. However, there is a dearth empirical studies that investigate how be associated with Using cross-sectional data collected from 791 people Guangxi China, we examined associations between these...

10.1080/09540121.2016.1146397 article EN cc-by-nc-nd AIDS Care 2016-02-22

Antiretroviral therapy (ART) is a lifelong treatment. To date, ART adherence suboptimal for most patients in resource-poor settings. Previous research indicates that medication side effects are perceived to be significant barrier of high adherence. Data regarding the role self-efficacy mediating relationship between from and limited; thus, this study examines potential mediational self-efficacy. A cross-sectional survey 2987 people living with HIV aged ≥18 years was conducted 2012–2013...

10.1080/09540121.2015.1124984 article EN AIDS Care 2016-03-24

Increasing risk of human immunodeficiency virus (HIV) heterosexual transmission can raise the potential for a more diffuse and generalized epidemic. In response to paucity data on HIV incidence among heterosexuals in China, we conducted large-scale, population-based cohort study located rural southwest China.Baseline enrollment was from 2013 2014 follow-up at 12 months 2015 adults 20 years or older 3 counties Southwest China. Study participants were informed by brochures leaflets distributed...

10.1097/olq.0000000000000957 article EN cc-by-nc-nd Sexually Transmitted Diseases 2018-12-05
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