- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Risk Factors
- Electrolyte and hormonal disorders
- Acute Kidney Injury Research
- Neonatal and fetal brain pathology
- Methemoglobinemia and Tumor Lysis Syndrome
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Healthcare professionals’ stress and burnout
- Neonatal Health and Biochemistry
- Traumatic Brain Injury and Neurovascular Disturbances
- Lung Cancer Diagnosis and Treatment
- Renal function and acid-base balance
- Diabetes Treatment and Management
- Heme Oxygenase-1 and Carbon Monoxide
- Liver Disease and Transplantation
- Acute Myocardial Infarction Research
- Radiation Dose and Imaging
- Workplace Health and Well-being
- Health and Wellbeing Research
- Educational Reforms and Innovations
- Genetic Associations and Epidemiology
- Chemotherapy-related skin toxicity
- Signaling Pathways in Disease
Xi'an Medical University
2021-2025
Kunming Medical University
2024
Beijing Anzhen Hospital
2011-2024
Capital Medical University
2021-2024
Air Force Medical University
2008-2023
Westlake University
2023
Chinese People's Liberation Army
2023
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2023
Zhejiang University
2007-2023
Chinese University of Hong Kong
2023
Background Community-acquired pneumonia (CAP) leads to high morbidity and mortality among the elderly, with 3 million deaths annually worldwide. Multiple comorbidities significantly increase risk. This study aims identify independent risk factors for in elderly patients CAP optimize individualized treatment strategies. Methods single-center retrospective was conducted at First Affiliated Hospital of Xi’an Medical University. Clinical data from diagnosed between December 2018 2023 were...
Background: Papillary thyroid cancer (PTC) is one of the most common endocrine malignancies with different risk levels. However, preoperative assessment PTC still a challenge in worldwide. Here, we first report Preoperative Risk Assessment Classifier for (PRAC-PTC) by multidimensional features including clinical indicators, immune indices, genetic feature, and proteomics. Materials methods: The 558 patients collected from June 2013 to November 2020 were allocated three groups: discovery set...
Abstract Introduction Shc adapter proteins are secondary messenger involved in various cellular pathways, including those mediating receptor tyrosine kinase signaling and apoptosis response to stress. We have previously reported that high levels of tyrosine-phosphorylated (PY-Shc) low its inhibitory p66 isoform strongly prognostic for identifying both early node-negative more advanced, node-positive, primary breast cancers with risk recurrence. Because aberrant activation kinases upstream...
Background/Objective: Many studies have focused on the effects of previous breastfeeding experience (PBE) subsequent breastfeeding, but few explored their specific relationships. To explain relationship between PBE and behavior based a follow-up study. Materials Methods: After delivery, 394 participants who had no completed demographic questionnaire, knowledge self-efficacy short-form scale (BSES-SF), Iowa infant feeding attitudes (IIFAS). Multiparas with also maternal evaluation (MBFES) in...
Chinese herbal medicine (CHM) is used among pregnant women. However, the question of its safety during pregnancy remains unclear. The use these products relies on history data but there are specific toxicities like developmental neurotoxicity that clearly understudied. Here we zebfrafish embryo toxicity assay (ZEDTA) in combination with two behavioral assays: touch-evoked response and Light/Dark (L/D) transition to evaluate neuro/developmental three commonly CHM [Chinese name (abbreviation;...
To investigate the male nurses' engagement in nursing work and influencing factors.A cross-sectional study.A survey was conducted 13 hospitals China to collect data from 328 nurses August October 2021. A structural equation model design tested with validated measurement instruments.The of at a medium level. There high correlation career identity (r = 0.764, p < 0.01), success 0.735, 0.01) social support 0.477, 0.01). The linear multivariate regression analysis showed that satisfaction (β...
Abstract Lung cancer is the leading cause of death worldwide. The Xuanwei-Fuyuan (XF) region Yunnan, China has a high incidence lung from coal-related pollution. Effort to raise public awareness screening for been ongoing. We retrospectively analyzed overall survival (OS) patients tertiary center in Yunnan investigate and regional residential status as predictive factors. Consecutive cases newly diagnosed were reviewed. by more likely be early-staged treated surgery than those not screening....
The number of patients awaiting kidney transplantation has more than doubled in the past decade while available donor organs seen only a modest increase, leading to critical shortage organs. In response this extreme shortage, criteria for accepting have been modified include marginal donors such as non-heart beating (NHBD). these kidneys, determining viability is important success transplantation. Therefore, study was undertaken develop system that would allow extracorporeal assessment...
There were controversial opinions on the use of regional citrate anticoagulation (RCA) versus low molecular weight heparin (LMWH) for continuous renal replacement therapy (CRRT) in hyperlactatemia patients, which was considered as one contraindications citrate. The aim our present study is to evaluate efficacy and safety RCA LMWH CRRT patients.Adult patients with who underwent or center between January 2014 March 2018 retrospectively recruited. Filter lifespan, ultrafiltration, purification,...
To evaluate and compare the effects toxicity of domestic product nrhTNF combined with chemotherapy in trial group alone control treatment patients non-small cell lung cancer (NSCLC).Ninety NSCLC multicenter were randomly devided into group. Each had 45 patients. Chemotherapy CAP regimen was given for Meanwhile, injection 4×10⁶U/m ² also from 1st to 7th days, 11th 17th days on course. Twenty-one as a cycle, 2 cycles each The chemothepeutic observed compared between two groups after therapy.Of...
Background and Aims: Bilirubin encephalopathy/kernicterus is very rare in adults.This study aimed to investigate the clinical manifestations genetic features of two patients with UGT1A1-related kernicterus.Methods: Sanger sequencing analysis was performed identify UGT1A1 gene mutations their families.Bioinformatics used predict potential functional effects novel missense mutations.Clinical biochemical parameters were collected analyzed.Results: Two Crigler-Najjar syndrome type II (CNS2)...
Severe hyperbilirubinemia after cardiac surgery increases in-hospital and 1-year mortality. Our present study aimed to analyze the safety efficacy of bilirubin adsorption (BA) in patients with post-cardiac-surgery severe hyperbilirubinemia.We retrospectively included who underwent BA due our center between January 2015 December 2018. The change serum bilirubin, alanine aminotransferase, aspartate 30-day mortality were assessed as endpoints. Univariate multivariate analyses employed identify...
<title>Abstract</title> Background The aim of this study was to explore the genetic-level associations membranous nephropathy and serum albumin concentrations with risk developing venous thromboembolism(VTE), encompassing deep-vein thrombosis lower extremities pulmonary embolism(PE), using bidirectional two-sample Mendelian randomization (MR) analysis. Methods Using summary-level data from large-scale genome-wide association studies (GWASs) in European individuals, study, MR employed examine...
This study aims to determine the long-term prognostic value of coronary hyper-intensity plaques and left ventricular (LV) myocardial strain for major adverse cardiac events (MACEs).
<title>Abstract</title> Objective To analyze the relationship between social support patterns and depression in elderly, to provide reference for improving system mental health of elderly. Methods Based on theory, latent category model was used explore among Chinese older adults. Results: The elderly can be categorized into Comprehensive provided by offspring, spouse, multiple support, intergenerational emotional detachment; tendency is most closely related offspring traditional concept...
<b><i>Purpose:</i></b> This study was aimed at evaluating the efficacy and safety of regional citrate anticoagulation (RCA) versus no-anticoagulation continuous venovenous hemofiltration (CVVH) in acute severe hypernatremia patients with increased bleeding risk. <b><i>Materials Methods:</i></b> Acute high risk who underwent CVVH our center between January 2011 October 2017 were considered as candidates. Patients &#x3c;18 years old,...