- Geology and Paleoclimatology Research
- Geomagnetism and Paleomagnetism Studies
- Paleontology and Stratigraphy of Fossils
- Geological and Geochemical Analysis
- Geological formations and processes
- Cryospheric studies and observations
- Cancer-related Molecular Pathways
- Evolution and Paleontology Studies
- Isotope Analysis in Ecology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Chromosomal and Genetic Variations
- Tea Polyphenols and Effects
- Long-Term Effects of COVID-19
- Geological and Tectonic Studies in Latin America
- earthquake and tectonic studies
- Geochemistry and Geologic Mapping
- Genomics and Chromatin Dynamics
- Marine Biology and Ecology Research
- Phytochemicals and Antioxidant Activities
- DNA Repair Mechanisms
- Skin Protection and Aging
- Geological and Geophysical Studies
- Wnt/β-catenin signaling in development and cancer
- Methane Hydrates and Related Phenomena
- Inflammasome and immune disorders
Temuco Catholic University
2018-2024
Universidad de La Frontera
2024
Millennium Institute on Immunology and Immunotherapy
2024
University of Concepción
2023
University of Otago
2014-2015
University of Chile
1994-2006
Universidade do Porto
1996
The results of a paleomagnetic study along the fore arc southern Peru (15–18°S) and northern Chile (18–19°S) are reported from middle to late Miocene ignimbrites (7 sites), Oligocene early (72 Paleogene sediments (20 Mesozoic Paleocene volcanics intrusions (31 sites). Comparison locality‐mean directions with expected indicates vertical axis rotations ranging 5.2 ± 11.3° clockwise 55.6 7.0° counterclockwise. Spatially, magnitude counterclockwise increases northward ∼0° within Chilean south...
Long-term pulmonary dysfunction (L-TPD) is one of the most critical manifestations long-COVID. This lung affection has been associated with disease severity during acute phase and presence previous comorbidities, however, clinical manifestations, concomitant consequences molecular pathways supporting this condition remain unknown. The aim study was to identify characterize L-TPD in patients long-COVID elucidate main long-term attributed by analyzing parameters functional tests supported...
ABSTRACT We report the molecular cloning and characterisation of first CK1(casein kinase) gene Drosophila melanogaster (dmCK1). The protein sequence (DMCK1) shares significant homology with other mammalian CK1 kinases α sub-class. dmCK1 is expressed only in adult females during early embryonic development as a single transcript. Western blot analysis total extracts different stages show that product likewise present embryogenesis females. Kinase activity studies DMCK1 active when vitro...
A cDNA clone coding for human protein kinase CK1 (casein 1) has been isolated and sequenced demonstrating that it corresponds to a homolog of the CK1α form found in bovine brain. The derived amino acid sequence is identical counterpart except contains 12 extra acids at carboxyl end. Using this PCR amplification, YAC genomic clones contain have isolated. These YACs used fluorescent situ hybridization order localize gene chromosome 13q13.
Photodynamic therapy (PDT) treats nonmelanoma skin cancer. PDT kills cells through reactive oxygen species (ROS), generated by interaction among cellular O
The cDNA coding for protein kinase CK1α has been cloned from a Xenopus laevis library. derived amino acid sequence of the contains 337 acids and calculated molecular mass 38 874 Da. is identical to that human bovine CK1α, except it 12 longer than latter protein. Southern blotting with 264‐bp probe demonstrates four or more fragments are obtained upon digestion genomic DNA Eco R1 Hin d3, suggesting X. possesses family related CK1 genes. was expressed in Escherichia coli as glutathione...
Orbital timescale, well-dated, shallow-marine records of the mid-Pliocene warm period (3.3–3.0 Ma) from tectonically uncomplicated continental margins are rare. They are, however, interest for understanding global sea level changes in a climate characterised by atmospheric CO2 concentrations ∼400 ppm and temperatures 2–3 °C warmer than pre-industrial times. We present here new high-resolution magnetostratigraphy two laterally adjacent drill cores (Tiriraukawa-1 Siberia-1) Whanganui Basin New...
Abstract Neogene sediments from La Portada and Bahia Inglesa formations located at Mejillones Peninsula Caldera Port, northern Chile carry multicomponent magnetizations, which can lead to misidentification of the characteristic paleomagnetic vector consequently, errors in chronostratigraphic structural interpretation strata. Here we present a complete rock magnetic behavior study formations. Isothermal remanent magnetization, thermal‐magnetic susceptibility, hysteresis, X‐ray diffractometer...
We present a paleomagnetic and rock magnetic record from 465.2 m long drill core recovered at DSDP Site 277 in the Southwest Pacific. Our study sought to construct magnetostratigraphy thus enable further paleoenvironmental work on this sedimentary succession. Magnetic remanence measurements revealed stable magnetisation upper 34.8 lower 58.7 of core. However, between 397.5 sediments are very weakly magnetised, do not carry magnetisation, analyses lack carrying minerals interval. suggest that...