A5062466206- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Influenza Virus Research Studies
- Heavy Metal Exposure and Toxicity
- Microplastics and Plastic Pollution
- Animal Virus Infections Studies
- Animal Nutrition and Physiology
- Computational Drug Discovery Methods
- Coccidia and coccidiosis research
- Animal Disease Management and Epidemiology
- Carcinogens and Genotoxicity Assessment
- Alzheimer's disease research and treatments
- Respiratory viral infections research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Fatty Acid Research and Health
- Antimicrobial Resistance in Staphylococcus
- Viral gastroenteritis research and epidemiology
- Proteins in Food Systems
- Herbal Medicine Research Studies
- Bone health and osteoporosis research
- Genomic variations and chromosomal abnormalities
- Ethnobotanical and Medicinal Plants Studies
- Trace Elements in Health
- Curcumin's Biomedical Applications
- Chronic Kidney Disease and Diabetes
King Abdulaziz University
2015-2024
Applications Research (United States)
2016-2020
King Fahd Armed Forces Hospital
2018
King Fahad Hospital Jeddah
2014
King Abdul Aziz University Hospital
2009-2013
Imam Abdulrahman Bin Faisal University
2013
A total of 20 organophosphate triesters (OPEs), including seven alkyl-OPEs, three chlorinated (Cl)-OPEs, aryl-OPEs, and oligomeric-OPEs were measured in 341 house dust samples collected from 12 countries during the period 2010-2014. OPEs ubiquitous indoor dust, concentrations (∑OPEs; sum OPEs) ranged 49.4 to 249,000 ng/g dry weight (dw). Generally, Cl-OPEs predominant compounds (51% total) samples, with a median concentration 800 ng/g, followed by alkyl-OPEs (31%), aryl-OPEs (17%), (1%),...
Abstract The oral bioavailability of many bioactives (pharmaceuticals, dietary supplements, nutrients, and nutraceuticals) is limited because physicochemical physiological events that occur within the gastrointestinal tract (GIT) after their ingestion. These include: (i) restricted liberation from drugs, or foods; (ii) extensive metabolism chemical transformation during passage through GIT; (iii) low solubility in intestinal fluids; (iv) permeation cell monolayer; (v) efflux epithelium...
Synthetic phenolic antioxidants (SPAs), including 2,6-di-tert-butyl-4-hydroxytoluene (BHT), are extensively used in food, cosmetic and plastic industries. Nevertheless, limited information is available on human exposures, other than the dietary sources, to SPAs. In this study, occurrence of 9 SPAs their metabolites/degradation products was determined 339 indoor dust collected from 12 countries. BHT found 99.5% samples homes microenvironments at concentrations that ranged < LOQ 118 μg/g 0.10...
Hepatocellular carcinoma (HCC) accounts for major cancer-related deaths despite current advanced therapies. Treatment and prognosis of HCC is better in patients with preserved liver function. Many natural products including ajwa dates (Phoenix dactylifera L.), are claimed to have hepatoprotective inhibitory effects, but most lack scientific validation. To prove our hypothesis, we attempted evaluate the other beneficial properties aqueous extract (ADE) a rat model diethylnitrosamine (DEN)...
Perchlorate is a widespread environmental contaminant and potent thyroid hormone disrupting compound. Despite this, very little known with regard to the occurrence of this compound in indoor dust exposure humans perchlorate through ingestion. In study, 366 samples were collected from 12 countries, USA, Colombia, Greece, Romania, Japan, Korea, Pakistan, Kuwait, Saudi Arabia, India, Vietnam, China, during 2010–2014. Dust extracted by 1% (v/v) methylamine water. Analyte separation was achieved...
Zingiber officinale Roscoe, one of the most widely used spices, has been reported to have anti-obesity and anti-diabetes effects. In present study, we investigated effects 6-shogaol, a bioactive compound in ginger, on adipogenic process 3T3-L1 preadipocytes. The anti-adipogenic 6-shogaol was significantly higher than more 6-gingerol, another major ginger constituent. We observed that inhibited expression two master regulators adipogenesis, PPARγ C/EBPα, also stimulated lipolysis mature...
L-asparaginase from bacteria has been used in treatment of acute lymphoblastic leukemia. The aim this study was to purify and characterize Phaseolus vulgaris seeds instead microbial sources. purified apparent homogeneity. enzyme molecular mass 79 kDa. asparaginase had very low activity toward a number asparagine glutamine analogues. free glutaminase activity. Kinetic parameters, Km V max enzyme, were found be 6.72 mM 0.16 μ M, respectively. optimum pH at 8.0. showed high stability alkaline...
Brucellosis is a common zoonosis that can cause severe febrile illness in humans. It constitutes persistent health problem many developing countries around the world. one of most frequently reported diseases Saudi Arabia and incidence particularly high Central region, city Riyadh. The aim this study was to evaluate two-stage PCR assay for detection human brucellosis endemic areas. A total 101 serum samples were collected from patients with acute (AFI) unknown two different locations Western...
Introduction: The World Health Organization’s persistent reporting of global outbreaks influenza A viruses, including the 2009 pandemic swine H1N1 strain (H1N1pdm09), justified targeted surveillance pilgrims during their annual congregation that pools more than two million people from around 165 nations in a confined area Makkah city Kingdom Saudi Arabia (KSA). Methodology: total 1,600 were included and Hajj (pilgrimage) season 2010. Each pilgrim responded to demographic health...