A5043960899- Lipoproteins and Cardiovascular Health
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Malaria Research and Control
- Retinal Diseases and Treatments
- Pericarditis and Cardiac Tamponade
- Biliary and Gastrointestinal Fistulas
- Retinal Development and Disorders
- Genetic Associations and Epidemiology
- Cardiac Structural Anomalies and Repair
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Colorectal Cancer Surgical Treatments
- Peripheral Artery Disease Management
- Cardiomyopathy and Myosin Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Drug-Induced Hepatotoxicity and Protection
- Coronary Interventions and Diagnostics
- Diverticular Disease and Complications
- Cancer-related molecular mechanisms research
- Nutrition, Genetics, and Disease
- Infective Endocarditis Diagnosis and Management
- Computational Drug Discovery Methods
- RNA regulation and disease
- Nuclear Structure and Function
Combined Military Hospital
2024
National University of Medical Sciences
2024
Northumbria Healthcare NHS Foundation Trust
2024
University of Azad Jammu and Kashmir
2023
University of Haripur
2015-2021
COMSATS University Islamabad
2010-2019
Portsmouth Hospitals NHS Trust
2017-2018
University College London
2012-2013
Baylor College of Medicine
2013
King Faisal Specialist Hospital & Research Centre
2013
Citrus black rot disease being caused by Alternaria citri is a major of citrus plants with 30-35% economic loss annually. Fungicides had not been effective in the control this during last few decades. In present study, antifungal role green synthesized zinc oxide (ZnO) and copper (CuO) nanoparticles (NPs) were studied against citri. was isolated from fruits samples identified staining lacto phenol cotton blue. Furthermore, CuO ZnO NPs utilizing lemon peels extract as reducing capping agent....
Continuous application of phosphate (P) mineral to soil renders apatite addition during each crop growing season which is great concern from a sustainable agriculture viewpoint. Use efficient solubilizing microbes (PSB) one the most effective ways solubilize this in soil. The current study targeted hydroxyapatite mines explore, isolate and characterize P solubilizers Efficiency isolated rock (hydroxyapatite) tri-calcium (TCP) as well indole-3-acetic acid (IAA)...
Background Numerous risk prediction algorithms based on conventional factors for Coronary Heart Disease (CHD) are available but provide only modest discrimination. The inclusion of genetic information may improve clinical utility. Methods We tested the use two gene scores (GS) in prospective second Northwick Park Study (NPHSII) 2775 healthy UK men (284 cases), and Pakistani case-control studies from Islamabad/Rawalpindi (321 cases/228 controls) Lahore (414 cases/219 controls). 19-SNP GS...
Background Homozygosity mapping has facilitated the identification of genetic causes underlying inherited diseases, particularly in consanguineous families with multiple affected individuals. This knowledge also resulted a mutation dataset that can be used cost and time effective manner to screen frequent population-specific variations associated diseases such as retinal disease (IRD). Methods We genetically screened 13 from cohort 81 Pakistani IRD diagnosed Leber congenital amaurosis (LCA),...
Allium cepa L. is a commonly consumed vegetable that belongs to the Amaryllidaceae family and contains nutrients antioxidants in ample amounts. In spite of valuable food applications onion bulb, its peel outer fleshy layers are generally regarded as waste exploration their nutritional therapeutic potential still progress with very slow progression rate. The present study was designed purpose doing comparative analysis antioxidant two parts cepa, i.g., bulb (edible part) dry peels (inedible...
In 1385 adults with primary untreated hyperlipidemia and in a population study of 339 (Princeton Follow-up Study [PFS]), we hypothesized that homeostasis model assessment (HOMA) insulin resistance (IR) was significant explanatory variable for triglycerides (TG) IR rose stepwise fashion, independent age, race, sex, body mass index (BMI), whereas TG categories from less than 150 to 200, 200 500, more 500 mg/dL. A third hypothesis TG, BMI, the ratio high-density lipoprotein cholesterol...
Familial hypercholesterolemia (FH) is an autosomal dominant disease caused by mutations in the genes coding for low density lipoprotein receptor (LDLR), proprotein convertase subtilisin/kexin type-9 (PCSK9) or apo-lipoprotein B-100 (APOB). The aim of present work was to determine genetic basis dyslipidemia 11 unrelated Pakistani families. High resolution melting (HRM), sequencing and restriction fragment length polymorphism (RFLP). Probands were screened promoter all regions, including...
Zearalenone (ZEA) is a secondary metabolite produced by Fusarium spp., the filamentous fungi. Food and feed contamination with zearalenone has adverse effects on health economy. ZEA degradation through microorganisms providing promising preventive measure. The current study includes isolation of 47 bacterial strains from 100 different food rumen samples. Seventeen isolates showed maximum activity reduction. A isolate, RS-5, reduced concentration up to 78.3% ELISA analysis 74.3% as determined...
In this present work, we demonstrated a spectral characterization of copper–iron (Cu-Fe) alloy using optical emission spectroscopy. The Cu-Fe plasma was generated on the target sample surface by directing laser pulse Q-switched Nd: YAG second harmonic (2ω) with 532 nm wavelength. spectrum acquired five miniature spectrometers that lie within wavelength range 200–720 nm. characterized validating local-thermodynamical equilibrium (LTE) as well optically thin (OT) condition. addition, LTE...
Xanthones C-glycosides are plants secondary metabolites with diverse biological activities. Among the C-glycoside xanthones, mangiferin (MF) is of widespread occurrence in while isomangiferin (IsoMF) not very common. For present study and were isolated from Dryopteris ramosa. The antibacterial potential MF IsoMF was evaluated by using agar well diffusion method cytotoxic properties assessed brine shrimp lethality test (BSLT). increases dose dependent manner. minimum inhibitory concentration...
Current published literature on hypertrophic cardiomyopathy (HCM) comes primarily from Western populations. There is no data clinical and echocardiographic characteristics long-term outcome of HCM in an Arab population.We conducted a retrospective analysis all patients 16 years or older diagnosed with at our institution. Detailed were collected was analyzed.A total 69 identified as having HCM. The mean age 42 ± 71% male patients. All Saudi citizens ancestry. Details about family history...
Plasma B-type natriuretic peptide (BNP) levels were obtained from 146 patients with unstable angina pectoris, non—ST-segment elevation myocardial infarction (MI), or ST-segment MI to determine their value in predicting the presence of new heart failure, recurrent ischemia, death 1 month after index event. Patients elevated plasma BNP (>80 pg/mL) had a significantly higher incidence failure and all-cause mortality than those normal level (≤80 pg/mL). Early revascularization percutaneous...
The aim of this study was to determine the genetic basis familial hypercholesterolemia in a Pakistani family with history myocardial infarction and premature coronary artery disease.Direct sequencing low-density lipoprotein receptor gene resulted identification novel missense mutation c.264G>C (p.R88S) exon 3 nonsense triple-nucleotide polymorphism (TNP) c.887-889GCA>AGC (p.C296X) 6, latter being probably disease-causing family. Both these mutations were not present probands 14 families, 100...
Wheat based products are consumed as staple food in most the of Asians countries, hence different wheat cultivars purposely developed to meet diverse ecological conditions. These carry difference their rheometry nutrition and gluten microstructure that affect overall product quality. In present investigation ten varieties were selected from two common zones i.e. rain fed irrigated. general, non-significant differences observed nutritional parameters however, tremendous variations studied...