- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Venous Thromboembolism Diagnosis and Management
- Chemical Reaction Mechanisms
- Advanced MRI Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Radical Photochemical Reactions
- Liver Disease and Transplantation
- Cyclopropane Reaction Mechanisms
- DNA and Nucleic Acid Chemistry
- Cancer Genomics and Diagnostics
- Central Venous Catheters and Hemodialysis
- Diagnosis and Treatment of Venous Diseases
- Organic and Inorganic Chemical Reactions
- MRI in cancer diagnosis
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis and biological activity
- COVID-19 diagnosis using AI
- Radiation Dose and Imaging
- Synthesis and Characterization of Heterocyclic Compounds
- Soft tissue tumor case studies
- Cancer Diagnosis and Treatment
Queen Elizabeth University Hospital
2018-2025
University of Glasgow
2020-2024
Government of the United Kingdom
2023
Glasgow Victoria Infirmary
2013-2017
New Victoria Hospital
2016
Glasgow Royal Infirmary
2012
The Gordon Hospital
2011
University of Edinburgh
2009
University Hospital Ayr
2008
Edinburgh Royal Infirmary
2007
The first page of this article is displayed as the abstract.
Background In malignant pleural mesothelioma (MPM), complex tumour morphology results in inconsistent radiological response assessment. Promising volumetric methods require automation to be practical. We developed a fully automated Convolutional Neural Network (CNN) for this purpose, performed blinded validation and compared CNN human classification survival prediction patients treated with chemotherapy. Methods multicentre retrospective cohort study; 183 CT datasets were split into training...
Artificial intelligence (AI)-assisted image interpretation is a fast-developing area of clinical innovation. Most research to date has focused on the performance AI-assisted algorithms in comparison with that radiologists rather than evaluating algorithms' impact clinicians who often undertake initial routine practice. This study assessed diagnostic frontline acute care for detection pneumothoraces (PTX).
IntroductionPleural Malignancy (PM) is often occult on subjective radiological assessment. We sought to define a novel, semi-objective Magnetic Resonance Imaging (MRI) biomarker of PM, targeted increased tumour microvessel density (MVD) and applicable minimal pleural thickening.Materials methods60 consecutive patients with suspected PM underwent contrast-enhanced 3-T MRI then biopsy. In 58/60, parietal pleura signal intensity (SI) was measured in multiple regions interest (ROI) at...
Hexachloroantimonate [SbCl6]– salts of stable organic cations are shown to be active oxidising agents for aromatic amines, ferrocene, phenoxide ions, and iodide ion. Tetra-alkylammonium hexachloroantimonates oxidise Leuco Crystal Violet by apparent hydride-abstraction. Kinetic studies show that the reactions have very low activation-energies an approximate value primary kinetic isotope effect kCH/kCD∼ 2·5. It is possible therefore functions primarily as a one-electron oxidant. Complex...
Background: Relatively little is known about prognosis in patients for whom suspected pulmonary embolism (PE) refuted by imaging.
J. N. Bradley, G. W. Cowell and A. Ledwith, Chem. Soc., 1964, 353 DOI: 10.1039/JR9640000353
J. N. Bradley, G. W. Cowell and A. Ledwith, Chem. Soc., 1964, 4334 DOI: 10.1039/JR9640004334
The kinetics of acetolysis 9-fluorenyl toluene-p-sulphonate have been studied. It is shown that the reaction SN1 type, and linear, normal salt effects are observed on addition lithium perchlorate. Added common ion, in form toluene-p-sulphonic acid, does not depress rate there was no maximum titrimetric coefficient with acetic anhydride to system. concluded occurs exclusion return from free ions, intermediates other than intimate ion-pairs.
<b>Introduction:</b> Optimal care in malignant pleural mesothelioma (MPM) requires specialist diagnostic tools, histology, and effusion management, providing a rationale for multi-disciplinary team (sMDT) working. The Scottish Mesothelioma Network, established April 2019, coordinates national sMDT provision of services. <b>Aims:</b> We hypothesize that is associated with improved overall survival MPM. <b>Methods:</b> All cases diagnosed 2017-January 2022 were allocated to pre- post-network...
Abstract: In malignant pleural mesothelioma (MPM), surgery may be offered for diagnostic or palliative purposes, in selected patients as part of a multi-modality radical treatment strategy. Imaging results are routinely used to select these settings. However, the initially subtle morphology and subsequent rind-like growth pattern primary tumour combined with complex space geometry unfamiliar nodal drainage present major challenges this regard. article, we summarize recent imaging...
The authors report a case of portal vein thrombosis, with no underlying malignant cause identified, which was initially detected by fludeoxyglucose positron emission tomography/CT (FDG PET/CT) and subsequently confirmed both contrast enhanced CT MRI. multimodality imaging findings are outlined, the potential clinical implications discussed note made possible FDG PET/CT mimics this disorder.
The hydrolysis of 9-fluorenyl toluene-p-sulphonate has been studied in various aqueous-organic solvents. In 90% aqueous acetone there is a linear relation between the specific rates and concentration added LiClO4 or NaBr. For same solvent alpha deuterium kinetic isotope effect kH/kD= 1·14. Increasing water content increased all these observations are taken to substantiate classical SN1-type reaction for rate-determining process.
Acute pancreatitis is associated with a number of well-known complications and imaging findings. Spontaneous recanalization the paraumbilical veins as consequence in patient an otherwise normal liver is, however, rare entity. This case report depicts this unusual complication gallstone non-cirrhotic no clinical or radiological evidence portal hypertension. There was followed by thrombosis, which believed to have propagated retrograde fashion into distal branches patent vein. A literature...
<h3>Introduction</h3> Recurrence following radical therapy for lung cancer remains common, potentially reflecting occult metastatic disease. In multiple retrospective studies, minimal pleural effusion (mini-PE) is associated with particularly high recurrence risk. Mini-PE defined as an ipsilateral (<1/3 hemithorax on chest radiograph), which cytology negative or too small safely aspirate. Thoracoscopy (Local Anaesthetic (LAT) Video Assisted Thoracoscopic Surgery (VATS)) the gold-standard...