Jinbao Gu

ORCID: 0000-0001-7784-8120
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Cancer-related molecular mechanisms research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Soybean genetics and cultivation
  • Plant Stress Responses and Tolerance
  • Cassava research and cyanide
  • Mosquito-borne diseases and control
  • Cancer, Lipids, and Metabolism
  • Photosynthetic Processes and Mechanisms
  • Genomics, phytochemicals, and oxidative stress
  • RNA Research and Splicing
  • Legume Nitrogen Fixing Symbiosis
  • RNA modifications and cancer
  • Plant pathogens and resistance mechanisms
  • Glutathione Transferases and Polymorphisms
  • RNA regulation and disease
  • Cancer, Hypoxia, and Metabolism
  • GABA and Rice Research
  • Plant nutrient uptake and metabolism
  • Plant Gene Expression Analysis
  • Plant responses to water stress
  • NF-κB Signaling Pathways
  • Cancer-related Molecular Pathways
  • Bladder and Urothelial Cancer Treatments
  • Plant Micronutrient Interactions and Effects

Guangdong Academy of Sciences
2021-2024

Zhanjiang Experimental Station
2024

Xuzhou Medical College
2022

The First People’s Hospital of Lianyungang
2020-2022

Nanjing Medical University
2013-2021

Hefei University of Technology
2019

Hainan University
2017

Jiangsu Province Hospital
2013-2015

Soil salinity is a significant threat to sustainable agricultural production worldwide. Plants must adjust their developmental and physiological processes cope with salt stress. Although the capacity for adaptation ultimately depends on genome, exceptional versatility in gene regulation provided by spliceosome-mediated alternative splicing (AS) essential these adaptive processes. However, functions of spliceosome plant stress responses are poorly understood. Here, we report in-depth...

10.1093/nar/gkx1229 article EN cc-by-nc Nucleic Acids Research 2017-12-01

The circadian system plays a pivotal role in facilitating the ability of crop plants to respond and adapt fluctuations their immediate environment effectively. Despite increasing comprehension PSEUDO-RESPONSE REGULATORs involvement regulation diverse biological processes, including rhythms, photoperiodic control flowering, responses abiotic stress, transcriptional networks associated with these factors soybean (Glycine max (L.) Merr.) remain incompletely characterized. In this study, we...

10.1093/plphys/kiae269 article EN PLANT PHYSIOLOGY 2024-05-08

Abstract Although many long noncoding RNAs have been discovered in plants, little is known about their biological function and mode of action. Here we show that the drought-induced intergenic RNA DANA1 interacts with L1p/L10e family member protein -INTERACTING PROTEIN 1 (DIP1) cell nucleus Arabidopsis, both DIP1 promote plant drought resistance. increase histone deacetylase HDA9 binding to CYP707A1 CYP707A2 loci. further PWWP3, a PEAT complex associates has activity. Mutation enhances...

10.1038/s44319-023-00030-4 article EN cc-by EMBO Reports 2024-01-02

Serine/arginine-rich (SR) proteins have an essential role in the splicing of pre-messenger RNA (pre-mRNA) eukaryote. Pre-mRNA with introns can be alternatively spliced to generate multiple transcripts, thereby increasing adaptation external stress conditions planta. However, pre-mRNA SR also different plant tissues and response diverse treatments, indicating that might involved regulating development environmental changes. We identified named 18 cassava systematically studied their...

10.1093/pcp/pcz190 article EN Plant and Cell Physiology 2019-10-08

Abstract Rapid postharvest physiological deterioration (PPD) of cassava (Manihot esculenta Crantz) storage roots is a major constraint that limits the potential this plant as food and industrial crop. Extensive studies have been performed to explore regulatory mechanisms underlying PPD processes in understand their molecular responses. However, exceptional functional versatility alternative splicing (AS) remains be explored during process cassava. Here, we identified several aberrantly...

10.1093/plphys/kiae206 article EN PLANT PHYSIOLOGY 2024-04-18

Background A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of NFKB1 gene was reported to influence expression and confer susceptibility different types cancer. This study aims determine whether is associated with risk bladder Materials methods TaqMan assay used genotype among 609 cases 640 controls a Chinese population. Logistic regression assess association between cancer risk, quantitative real-time polymerase chain reaction mRNA expression. Results Compared...

10.1371/journal.pone.0071604 article EN cc-by PLoS ONE 2013-08-20

Abstract Identification and characterization of soybean germplasm gene(s)/allele(s) for salt tolerance is an effective way to develop improved varieties saline soils. Previous studies identified GmCHX1 (Glyma03g32900) as a major gene in soybean, two main functional variations were found the promoter region (148/150 bp insertion) third exon with retrotransposon insertion (3.78 kb). In current study, we four salt-tolerant lines, including PI 483460B (Glycine soja), carrying previously...

10.1093/jxb/erad404 article EN cc-by Journal of Experimental Botany 2023-10-21

This study aimed to explore the function of LINC00665 on proliferation and metastasis prostate cancer (PCa), potential regulatory mechanisms were also investigated. The expression level in 50 pairs PCa tissues adjacent ones was studied by qRT-PCR, associations between clinicopathological characteristics patients analyzed. Control group (sh-NC) knock-down (sh-LINC00665) set 22RV1 DU145 cells, respectively. biological functions cell lines assessed CCK-8, EdU, Transwell assays, nude mouse...

10.3389/fonc.2021.639060 article EN cc-by Frontiers in Oncology 2021-05-20

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTT.cntdot.C.cntdot.G triplet in an antiparallel purine.cntdot.purine.cntdot.pyrimidine DNA triplex. conformational studies by NMRKaren Dittrich, Juan Gu, Robert Tinder, Michael Hogan, and Xiaolian GaoCite this: Biochemistry 1994, 33, 14, 4111–4120Publication Date (Print):April 12, 1994Publication History Published online1 May 2002Published inissue 12 April...

10.1021/bi00180a003 article EN Biochemistry 1994-04-12

Soil salinity is a significant threat to sustainable agricultural production. Plants must adjust their developmental and physiological processes deal with environmental salt conditions. We previously identified 18 serine-arginine-rich (SR) proteins from cassava (Manihot esculenta Crantz) that play pivotal roles in alternative splicing when encountering the external stress condition. However, functional characterisation of SR less reported cassava, which an important staple crop world. In...

10.1071/fp21165 article EN Functional Plant Biology 2021-10-03

To find potential serum biomarkers for upper tract urothelial carcinomas (UTUCs) via (1)H nuclear magnetic resonance ((1)H NMR)-based metabolomic analysis. Serum specimens collected from 34 healthy individuals and 39 patients with UTUCs were subjected to NMR-based Principal component orthogonal partial least squares discriminant analyses used analyse the data. Compared samples subjects, UTUC showed elevated levels of lactate creatinine as well decreased glucose, glutamine taurine....

10.1007/s13277-015-3482-3 article EN Tumor Biology 2015-04-27

Soil salinity affects the expression of serine/arginine-rich (SR) genes and isoforms by alternative splicing, which in turn regulates adaptation plants to stress. We previously identified cassava spliceosomal component 35 like (SCL) SR subfamilies, belonging protein family, are extensively involved responses abiotic stresses. However, post-transcriptional regulatory mechanism arginine/serine-rich (RS) subfamily response salt stress remains be explored. In current study, we 37 RS from 11...

10.1016/j.jia.2023.04.003 article EN cc-by-nc-nd Journal of Integrative Agriculture 2023-04-14
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