A5004412221- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Neuroscience and Music Perception
- Hearing Loss and Rehabilitation
- Educational and Psychological Assessments
- Mental Health Treatment and Access
- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Child and Adolescent Psychosocial and Emotional Development
- Hearing, Cochlea, Tinnitus, Genetics
- Psychiatric care and mental health services
- Attention Deficit Hyperactivity Disorder
- Neural and Behavioral Psychology Studies
- Traumatic Brain Injury Research
- Noise Effects and Management
- Mental Health and Patient Involvement
- Aesthetic Perception and Analysis
- Tryptophan and brain disorders
- Digital Mental Health Interventions
- Telemedicine and Telehealth Implementation
- Adolescent and Pediatric Healthcare
- Motivation and Self-Concept in Sports
- Diet and metabolism studies
Columbia University
2015-2025
New York State Office of Mental Health
2014-2024
University of Pittsburgh
2024
City University of New York
2022
The Graduate Center, CUNY
2022
Columbia University Irving Medical Center
2013-2019
New York State Psychiatric Institute
2014-2019
New York Psychoanalytic Society and Institute
2015-2019
Behavioral Health Services
2017-2018
New York University
2017
<h3>Background</h3> Patients with schizophrenia show deficits in early-stage visual processing, potentially reflecting dysfunction of the magnocellular pathway. The system operates normally a nonlinear amplification mode mediated by glutamatergic (<i>N</i>-methyl-D-aspartate) receptors. Investigating therefore permits evaluation underlying etiologic hypotheses. <h3>Objectives</h3> To evaluate schizophrenia, relative to known neurochemical and neuroanatomical substrates, examine relationships...
Intrinsic motivation is a construct commonly used in explaining goal-directed behavior. In people with schizophrenia, intrinsic usually subsumed as feature of negative symptoms or underlying neurocognitive dysfunction. A growing literature reflects an interest defining and measuring motivational impairment schizophrenia delineating the specific role both independent predictor mediator psychosocial functioning. This cross-sectional study examined vocational outcomes for 145 individuals...
Early auditory processing (EAP) has increasingly become a focus of efforts to identify markers treatment response in people with schizophrenia spectrum disorders. Assessment baseline need provides an opportunity for cognitive remediation (CR) programs that include EAP training personalize and optimize its impact. CR been shown help reduce negative symptoms, but less is known about how tailoring may influence this relationship. This study hypothesized differential benefit on symptom reduction...
Research suggests that first-degree relatives and individuals with schizophrenia spectrum personality disorders (SSPD) may represent nonpenetrant carriers of the genetic diathesis for schizophrenia. This study examined visuospatial working memory (SWM) as a cognitive endophenotype by expanding concept risk pathophysiological dysfunction beyond overt psychosis. Risk was thus defined familial status presence or absence SSPD. SWM assessed in following groups, order decreasing likelihood...
Cognitive deficits are a well-recognised issue for individuals diagnosed with schizophrenia spectrum disorders. Despite positive group findings the use of cognitive remediation (CR) interventions, there substantial individual differences in response to treatment. In addition, aggregate CR literature reports low moderate effect sizes and functional outcomes. Based on personalised medicine theory, this paper uses extant examine characteristics determined predict treatment response. These...
Abstract To date, no measures are available that permit differentiation of discrete, clinically distinct subtypes schizophrenia (SZ) with potential differential underlying pathophysiologies. Over recent years, there has been increasing recognition SZ is heterogeneously associated deficits in early auditory processing (EAP), as demonstrated using applicable tasks such tone-matching task (TMT). Here, we pooled TMT performances across 310 individuals and 219 healthy controls (HC), along...
Abstract Background and Hypothesis With increasing recognition of the importance cognitive health for recovery in people with psychosis, questions arise as to how implement services large systems care. This paper describes implementation OnTrackNY (OTNY), a network clinics delivering Coordinated Specialty Care treatment model early goal documenting processes, challenges, useful adaptations. Study Design In 2018, OTNY piloted Cognitive Health Toolkit across 18 affiliated clinics. The toolkit...
The COVID-19 crisis and subsequent stay-at-home orders have produced unprecedented challenges to the dissemination of recovery oriented behavioral health services (RS) that support treatment those with complex psychosis (CP).This population has typically been managed in-person pharmacotherapy and/or RS, goals relieving symptoms, improving life satisfaction increasing community engagement. related social distancing measures required rapid shifts in care management, while easing telehealth...