- Sleep and related disorders
- Sleep and Work-Related Fatigue
- Obesity, Physical Activity, Diet
- Sleep and Wakefulness Research
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
- Circadian rhythm and melatonin
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Urban Transport and Accessibility
- Health disparities and outcomes
- Mental Health Treatment and Access
- Obstructive Sleep Apnea Research
- Nutritional Studies and Diet
- Maternal Mental Health During Pregnancy and Postpartum
- Suicide and Self-Harm Studies
- Diet, Metabolism, and Disease
- Neuroscience and Neuropharmacology Research
- Birth, Development, and Health
- Cardiac Health and Mental Health
- Workaholism, burnout, and well-being
- Treatment of Major Depression
- Impact of Light on Environment and Health
- Genetics and Neurodevelopmental Disorders
- Cardiovascular Health and Risk Factors
Columbia University
2011-2023
New York State Psychiatric Institute
2018-2023
New York Psychoanalytic Society and Institute
2018-2023
Nathan Kline Institute for Psychiatric Research
2015
University of Miami
2015
Columbia College
2009
Royal College of Physicians
2009
Universidad de Xalapa
2006
Netherlands Institute for Neuroscience
2006
Merck & Co., Inc., Rahway, NJ, USA (United States)
2006
Depriving healthy subjects of sleep has been shown to acutely increase blood pressure and sympathetic nervous system activity. Prolonged short durations could lead hypertension through extended exposure raised 24-hour heart rate, elevated activity, increased salt retention. Such forces structural adaptations the entrainment cardiovascular operate at an equilibrium. Sleep disorders are associated with disease, but we not aware any published prospective population studies that have a link...
Sleep is essential for optimal health. The American Academy of Medicine (AASM) and Research Society (SRS) developed a consensus recommendation the amount sleep needed to promote health in adults, using modified RAND Appropriateness Method process. summarized here. A manuscript detailing conference proceedings evidence supporting final statement will be published SLEEP Journal Clinical Medicine.
Sleep is essential for optimal health. The American Academy of Medicine (AASM) and Research Society (SRS) developed a consensus recommendation the amount sleep needed to promote health in adults, using modified RAND Appropriateness Method process. summarized here. A manuscript detailing conference proceedings evidence supporting final statement will be published SLEEP Journal Clinical Medicine.
Sleep deprivation has been hypothesized to contribute toward obesity by decreasing leptin, increasing ghrelin, and compromising insulin sensitivity. This study examines cross-sectional longitudinal data from a large United States sample determine whether sleep duration is associated with weight gain.Longitudinal analyses of the 1982-1984, 1987, 1992 NHANES I Followup Studies analysis 1982-1984 study.Probability civilian noninstitutionalized population States.Sample sizes 9,588 for analyses,...
The American Academy of Sleep Medicine and Research Society recently released a Consensus Statement regarding the recommended amount sleep to promote optimal health in adults. This paper describes methodology, background literature, voting process, results for consensus statement. In addition, we address important assumptions challenges encountered during process. Finally, outline future directions that will advance our understanding need place duration broader context health.
To explore the relationship between sleep duration and diabetes incidence over an 8- to 10-year follow-up period in data from First National Health Nutrition Examination Survey (NHANES I). We hypothesized that prolonged short is associated with obesity hypertension act as partial mediators of this relationship. The increased load on pancreas insulin resistance induced by chronically durations can, time, compromise beta-cell function lead type 2 diabetes. No plausible mechanism has been...
The American Academy of Sleep Medicine and Research Society recently released a Consensus Statement regarding the recommended amount sleep to promote optimal health in adults.This paper describes methodology, background literature, voting process, results for consensus statement.In addition, we address important assumptions challenges encountered during process.Finally, outline future directions that will advance our understanding need place duration broader context health.
Poor nutrition may be a causal factor in the experience of low mood, and improving diet help to protect not only physical health but also mental population, say <b>Joseph Firth colleagues</b>
To examine the relationships between parental set bedtimes, sleep duration, and depression as a quasi-experiment to explore potentially bidirectional relationship short duration depression. Short has been shown precede depression, but this could be explained prodromal symptom of Depression in an adolescent can affect his/her chosen bedtime, it is less likely parent's bedtime which establish relatively stable upper limit that directly duration. Multivariate cross-sectional analyses ADD Health...
Participation in sports has been shown to be protective against depression and suicidal ideation, but little is known about what factors mediate these relationships. No previous studies examined potential mediators between participation ideation only one study explored possible depression. Increased could protect by increasing endogenous endorphin levels, boosting self-esteem, improving body image, social support, affecting substance abuse.Multivariate hierarchical logistic regression...
To explore age differences in the relationship between sleep duration and mortality by conducting analyses stratified age. Both short long durations have been found to be associated with mortality. Short is negative health outcomes, but there little evidence that has adverse effects. No epidemiologic studies published multivariate age, even though life expectancy 75 years majority of deaths occur elderly. Multivariate longitudinal first National Health Nutrition Examination Survey using Cox...
Study Objectives:To explore the relationship between sleep duration in adolescence and hypercholesterolemia young adulthood. Experimental restriction has been shown to significantly increase total cholesterol LDL levels women. Short found cross sectional studies be associated with higher lower HDL levels. Sleep deprivation could risk for by increasing appetite dietary consumption of saturated fats, decreasing motivation engage regular physical activity, stress resultant catecholamine induced...
Depression has been found to predict the incidence of hypertension and other adverse cardiovascular events in prospective studies. Insomnia short sleep duration, which are typical symptoms depression, have also shown increase risk for incidence. is associated with increased activation hypothalamic-pituitary-adrenal axis, duration raises average 24-h blood pressure, over time could lead structural adaptations that gradually reset entire system operate at an elevated pressure equilibrium. No...
Acute sleep restriction has been shown to increase blood pressure and sympathetic nervous system activity. We investigated the relationships between duration hypertension among women whose durations were self-reported in 1986 (n = 82,130) 2000 71,658) Nurses' Health Study I (NHS-I) 2001 84,674) II (NHS-II). After controlling for multiple risk factors logistic regression models, prevalence of was significantly higher all 3 groups who slept ≤5 hours (odds ratio 1.19, 95% confidence interval...
Abstract Decades of research have highlighted the importance optimal stimulation cortical dopaminergic receptors, particularly D1R receptor (D1R), for prefrontal-mediated cognition. This mechanism is relevant to cognitive deficits in schizophrenia, given abnormalities dopamine (DA) neurotransmission and expression D1R. Despite critical need D1R-based therapeutics, many factors complicated their development prevented this important therapeutic target from being adequately interrogated....
Abstract Background The relationship between inadequate sleep duration and hypertension risk has been established in the general population, but there is a gap literature on predictors of habitual adults with hypertension. This study examined factors associated among United States (US). Methods Data 5660 were obtained by combining 2015–2018 cycles National Health Nutrition Examination Survey (NHANES). weighted multinomial logistic regression models fit to examine short (< 7 h) long (>...