- MRI in cancer diagnosis
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Prostate Cancer Diagnosis and Treatment
- Renal and related cancers
- Pancreatic and Hepatic Oncology Research
- Advanced MRI Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Neuroendocrine Tumor Research Advances
- Adrenal and Paraganglionic Tumors
- Tuberous Sclerosis Complex Research
- Sarcoma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Liver Disease and Transplantation
- Advanced Neuroimaging Techniques and Applications
- Genetic and Kidney Cyst Diseases
- Bladder and Urothelial Cancer Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Endometriosis Research and Treatment
- Obsessive-Compulsive Spectrum Disorders
- Mesoporous Materials and Catalysis
Chinese PLA General Hospital
2016-2025
South China Normal University
2021-2022
Chinese People's Liberation Army
2015-2019
People's Liberation Army No. 150 Hospital
2019
Christie's
2015
Pingdingshan University
2015
Creative Commons
2015
Beijing Hospital
2007
Xiaomi (China)
2002
Over 70% of the patients with hepatocellular carcinoma (HCC) are diagnosed at an advanced stage and lose opportunity for radical surgery. Combination therapy tyrosine kinase inhibitors (TKIs) anti-programmed cell death protein-1 (PD-1) antibodies has achieved a high tumor response rate in both first-line second-line treatment HCC. However, few studies have prospectively evaluated whether TKIs plus anti-PD-1 could convert unresectable intermediate-advanced HCC into resectable disease.This...
To assess the usefulness of apparent diffusion coefficients (ADCs) for characterizing renal cell carcinoma (RCC) subtypes at 3.0 T.The Institutional Review Board approved this retrospective study, and informed consent was waived. Eighty-three patients underwent diffusion-weighted (DW) magnetic resonance (MR) imaging 85 masses. In each patient, precontrast single-shot spin-echo echo-planar DW performed with b values 0 500 800 sec/mm(2) by using a 3.0-T MR system. Differences in ADCs between...
Immunotherapy with PD-1 inhibitors combined tyrosine kinase (TKIs) has been proven to be effective against advanced hepatocellular carcinoma (HCC). The aim of this study was identify the feasibility and safety subsequent salvage surgery after combination therapy.A retrospective analysis performed on patients primary HCC major vascular invasion between 2018 2019. All cases were treated a inhibitor TKI agents surgery.A total 10 met successful conversion criteria therapy, eight underwent both...
Background The 2019 Bosniak classification (version 2019) of cystic renal masses (CRMs) provides a systematic update to the currently used 2005 2005). Further validation is required before widespread application. Purpose To evaluate interobserver agreement MRI criteria, impact readers' experience, and diagnostic performance between version 2005. Materials Methods From January 2009 December 2018, consecutive patients with CRM who had undergone surgical-pathologic examination were included in...
To determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas.The features of 50 patients with confirmed schwannomas were retrospectively reviewed by two radiologists blinded to the histopathologic diagnosis. These compared between types tumours use Mann-Whitney test binary logistic regression. The patients' clinical characteristics reviewed.Analysis images from revealed no significant differences in quantitative lesion size,...
Background Nuclear grade is of importance for treatment selection and prognosis in patients with clear cell renal carcinoma (ccRCC). Purpose To develop validate an MRI‐based radiomic model preoperative predicting WHO/ISUP nuclear ccRCC. Study Type Retrospective. Population In all, 379 histologically confirmed Training cohort ( n = 252) validation 127) were randomly assigned. Field Strength/Sequence Pretreatment 3.0T MRI. Imaging sequences fat‐suppressed T 2 WI, contrast‐enhanced 1 diffusion...
Preoperative renal tumor subtype differentiation is important for radiology and urology in clinical practice. Pharmacokinetic data (K trans & V e, etc.) derived from dynamic contrast-enhanced MRI (DCE-MRI) have been used to investigate vessel permeability. In this prospective study on DCE-MRI pharmacokinetic studies, we enrolled patients with five common subtypes: clear cell carcinoma (ccRCC; n = 65), papillary (pRCC; 12), chromophobic (cRCC; 9), uroepithelial (UEC; 14), fat-poor...
Abstract Pharmacokinetic parameters derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) have been increasingly used to evaluate the permeability of tumor vessel. Histogram metrics are a recognized promising method quantitative MR that has recently introduced in analysis DCE-MRI pharmacokinetic oncology due heterogeneity. In this study, 21 patients with renal cell carcinoma (RCC) underwent paired studies on 3.0 T system. Extended Tofts model and population-based...
Background Routine screening of prostate specific antigen (PSA) is no longer recommended because a high rate over-diagnosis cancer (PCa). Objective To evaluate the efficacy diffusion-weighted magnetic resonance imaging (DW-MRI) for PCa detection, and to explore clinical utility ultrahigh b-value DW-MRI in predicting biopsy outcomes. Methodology 73 male patients were selected study. They underwent 3T MRI using T2WI conventional with 1000 s/mm2, b-values 2000 s/mm2 3000 s/mm2. Two radiologists...
The purpose of our study was to evaluate the role contrast-enhanced ultrasound (CEUS) with magnetic resonance imaging (MRI) and computed tomography (CT) in pathological diagnosis pancreatic cystic neoplasms (PCNs).A total 90 patients (66 women, 24 men) aged 18-71 years were studied prospectively. CEUS performed all patients, whereas MRI 85 CT 69 patients. We analyzed sensitivity accuracy these three modalities diagnose PCNs. Neoplasm size, location, shape, intralesional mural nodules, septa...