A5100711851- Blood groups and transfusion
- Renal cell carcinoma treatment
- Blood disorders and treatments
- Renal and related cancers
- Erythrocyte Function and Pathophysiology
- Urologic and reproductive health conditions
- Prostate Cancer Treatment and Research
- Pediatric Urology and Nephrology Studies
- Immunotherapy and Immune Responses
- Schizophrenia research and treatment
- Metabolomics and Mass Spectrometry Studies
- solar cell performance optimization
- Cholesterol and Lipid Metabolism
- Immunodeficiency and Autoimmune Disorders
- Natural product bioactivities and synthesis
- Cardiovascular Disease and Adiposity
- Greenhouse Technology and Climate Control
- Ultrasound and Hyperthermia Applications
- Genital Health and Disease
- Urinary and Genital Oncology Studies
- Alcohol Consumption and Health Effects
- Ultrasound Imaging and Elastography
- Blood transfusion and management
- Nanoparticle-Based Drug Delivery
- Blood Pressure and Hypertension Studies
Anhui Medical University
2008-2025
First Affiliated Hospital of Anhui Medical University
2008-2025
Second Hospital of Shandong University
2025
Jiangsu University
2024
Chinese PLA General Hospital
2020-2024
China Medical University
2024
Affiliated Hospital of Jiangsu University
2024
Hebei Medical University
2022
Second Hospital of Hebei Medical University
2022
Harbin Medical University
2019
Background The 2019 Bosniak classification (version 2019) of cystic renal masses (CRMs) provides a systematic update to the currently used 2005 2005). Further validation is required before widespread application. Purpose To evaluate interobserver agreement MRI criteria, impact readers' experience, and diagnostic performance between version 2005. Materials Methods From January 2009 December 2018, consecutive patients with CRM who had undergone surgical-pathologic examination were included in...
We aimed to determine the abilities of several drugs block second methylation process severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA with non-structural protein 16 (NSP16) and expose virus innate immune mechanism host for purpose improving infection control drug development COVID-19. Recombinant prokaryotic expression plasmids PET30a-NSP16 PET15b-NSP10 a plasmid preserving untranslated region (UTR) sequences, pUC57-UTR, were constructed. The obtained UTR template was...
In recent years, the primary treatments for cancer have included chemotherapy, radiotherapy, and surgery. However, challenges such as poor prognosis, high recurrence rates, low survival diminished quality of life persist in management. Recently, immunotherapy has emerged a potent therapeutic approach treating tumors. To this end, we developed antibodies mucin 1 (MUC1) programmed cell death ligand (PD-L1) to functionalize liposomes incorporate doxorubicin (DOX) (DOX-aMUC1/aPDL1-Lip). This...
<i>Salviae miltiorrhiza</i>, a traditional Chinese medical herb known as "Danshen," has been widely used in clinics to improve blood circulation, relieve stasis, and treat coronary heart disease. Depside salts from <i>S. miltiorrhiza</i> are novel drug which magnesium lithospermate B its analogs the active components. The pharmacokinetics, tissue distribution, metabolism, excretion of three major components, lithospermic acid B, rosmarinic (RA), (LA), were studied by liquid...
SUMMARY Objectives To analyse anti‐D alloimmunisation in pregnant women with D‐elute ( DEL ) phenotype China, for developing a predictive model to evaluate whether person the can receive RhD ‐positive blood. Background Alloanti‐D acquired by pregnancy or transfusion is one of major causes both haemolytic disease among newborns and reactions. date, there little data available about antigenic properties immunogenicity extremely weak D variants known as . Methods RHD genotyping epitope mapping...
Instrument-based scores are often used as outcome measures. However, little is known about what changes in mean terms of a clinical assessment improvement or deterioration. The purpose this report was to determine how much change standard instrument represents clinically detectable Veterans Affairs (VA) Cooperative Study Clozapine Refractory Schizophrenia evaluated 423 patients on clozapine haloperidol. Symptoms and quality life scales were completed at baseline; 6 weeks; 3, 6, 12 months....
Recently, a large genome-wide association study has revealed that polymorphism of alleles and genotypes in rs3,764,650 within ABCA7 gene is associated with Alzheimer disease whites. We conducted case-control to investigate whether these susceptible genetic variants are risk factors for sporadic (SAD) Chinese Han population.A total 633 participants consisting 350 SAD 283 nondemented elderly controls matched sex age were recruited (rs3,764,650) genotyped using DNA sequencing.On the basis...
The D antigen is highly immunogenic, requiring only a small quantity of transfused red blood cells (RBCs) to cause alloimmunization in D- immunocompetent recipients. DEL was reported arousing true Rh- patients. Molecular studies the RHD gene have revealed that individuals retain grossly intact or portion their genomes. Avoiding immunization with clinically important antibodies primary objective transfusion medicine.In order determine whether pregnant women carrying an RhD+ fetus are at risk...
<b><i>Background: </i></b>During the transfusion of blood components, transfer allogeneic donor white cells (WBCs) can mediate transfusion-associated graft-versus-host disease (TA-GVHD). To minimize reaction, exposure products to gamma irradiation is currently standard care. The aim our study was evaluate and compare hemostatic function, efficacy, safety gamma-irradiated single-donor apheresis platelet concentrates (PCs) conventional non-irradiated PCs in patients...
Monocyte-derived dendritic cells (DCs) are used as immunoadjuvant in cancer vaccines and have made great progress. However, an optimal DCs subset is vital for this treatment effect, the current 'gold standard' cytokine cocktail a shortcoming their cytokines secretion, especially IL-12p70, mainly because of existence PGE2. Therefore, it necessary to find appropriate DCs-based immunotherapeutic protocol. In study, we compared novel 'improved' maturation with generating standard DCs. The showed...
A consensus has not been reached on the value of prostate-specific antigen density (PSAD) as a predictor biochemical recurrence prostate cancer. This meta-analysis aimed to evaluate association between PSAD and cancer after primary treatment.
Background and Objective: Increasing evidence suggested that polymorphisms in genes of PI3K/Akt pathway were closely related to prostate cancer (PCa) risk. Nevertheless, these results are controversial inconclusive. Here, we conducted a comprehensive updated meta-analysis systematic review precisely illustrate the association between signaling PCa Materials Methods: The gene set was referenced from Kyoto Encyclopedia Genes Genomes (KEGG) website. Relevant studies identified by systematically...
To investigate the association between TGFA:c.3851T > C (rs11466285) and TGFA:c.3822G A (rs3771523) single-nucleotide polymorphisms (SNPs) nonsyndromic cleft lip and/or palate (CL/P) with microarray in north China.Test by both case-control case-parent analysis.Two SNPs of 150 controls, 166 cases, 271 their parents were genotyped using based on allele-specific primer extension, chi-square statistics family-based test analyses performed.Both sequencing analysis produced identical results. We...