A5089432488- Advanced biosensing and bioanalysis techniques
- Gene expression and cancer classification
- Advanced Biosensing Techniques and Applications
- Biosensors and Analytical Detection
- Genomics and Phylogenetic Studies
- Molecular Biology Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Nanofabrication and Lithography Techniques
- Bacteriophages and microbial interactions
- Gut microbiota and health
- RNA and protein synthesis mechanisms
- bioluminescence and chemiluminescence research
- Clostridium difficile and Clostridium perfringens research
- Genomics and Chromatin Dynamics
- Polymer Surface Interaction Studies
- DNA and Nucleic Acid Chemistry
- DNA and Biological Computing
- SARS-CoV-2 detection and testing
- Additive Manufacturing and 3D Printing Technologies
- Protist diversity and phylogeny
- Surface Modification and Superhydrophobicity
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microbial Community Ecology and Physiology
- Pediatric health and respiratory diseases
- Molecular Junctions and Nanostructures
Southeast University
2016-2025
Guangxi University
2025
Wenzhou University
2024
State Key Laboratory of Digital Medical Engineering
2014-2024
Jilin Vocational College of Industry and Technology
2013-2023
The University of Texas MD Anderson Cancer Center
2021
University of Maryland, Baltimore County
2017
China Pharmaceutical University
2016
Harbin Institute of Technology
2016
Harbin University
2016
Abstract Bioinspired re‐entrant structures have been proved to be effective in achieving liquid superrepellence (including anti‐penetration, anti‐adhesion, and anti‐spreading). However, except for a few reports relying on isotropic etching of silicon wafers, most fluorination‐dependent surfaces are still unable repel liquids with extreme low surface energy (i.e., γ < 15 mN m −1 ), especially those fluorinated solvents. Herein, triply structures, possessing water (with tension 72.8 )...
Surfaces combining antispreading and high adhesion can find wide applications in the manipulation of liquid droplets, generation micropatterns enrichment. To fabricate such surfaces, almost all traditional methods demand multi-step processes chemical modification. And even so, most them cannot be applied for some liquids with extremely low surface energy. In past decade, multiply re-entrant structures have aroused much attention because their universal modification-independent antiadhesion...
Digital information, when converted into a DNA sequence, provides dense, stable, energy-efficient, and sustainable data storage. The most stable method for encapsulating has been in an inorganic matrix of silica, iron oxide, or both, but are limited by low uptake complex recovery techniques. This study investigated rationally designed thermally responsive functionally graded (TRFG) hydrogel as simple cost-effective storing DNA. TRFG shows high uptake, long-term protection, reusability due to...
A sustainable and efficient approach for converting carbohydrates into 5-hydroxymethylfurfural (HMF) via heterogeneous catalysis is crucial effectively utilizing biomass. In this study, we synthesized a series of CrX-polyphenol-formaldehyde resin (PTF) catalysts, which are composites Cr-doped phenolic-resin-based hydrothermal carbon, using chelation-assisted multicomponent co-assembly strategy. The performance the catalysts was assessed through various analytical techniques, including...
ABSTRACT Viral hemorrhagic septicemia virus (VHSV) is a pathogenic fish rhabdovirus found in discrete locales throughout the Northern Hemisphere. VHSV infection of cells leads to upregulation host's detection response, but quickly suppresses interferon (IFN) production and antiviral gene expression. By systematically screening each six structural nonstructural genes, we identified matrix protein (M) as virus' most potent antihost protein. Only M genotype IV sublineage b (VHSV-IVb) suppressed...
Abstract Aim Long noncoding RNAs (lncRNAs) are key mediators with a wide range of pathophysiological functions, but their role in human hepatocellular carcinoma (HCC) is still unclear. Methods An unbiased microarray study evaluated novel lncRNA, HClnc1, that linked to the development HCC. In vitro cell proliferation assays and an vivo xenotransplanted HCC tumor model were performed determine its followed by antisense oligo‐coupled mass spectrometry identify HClnc1‐interacting proteins. To...
BackgroundA low-clean living environment (LCLE) can increase gut microbial diversity and prevent allergic diseases, whereas dysbiosis is closely related to the pathogenesis of asthma. Our previous studies suggested that soil in LCLE a key factor shaping intestinal microbiota. We aimed explore whether sterilized intake as prebiotic while being incubated with microbes air attenuate mouse asthma inflammation by modifying microbiota.Methods16S rRNA gene sequencing was used analyze composition,...
Introduction In riverine ecosystems, dynamic interplay between hydrological conditions, such as flow rate, water level, and rainfall, significantly shape the structure function of bacterial microeukaryotic communities, with consequences for biogeochemical cycles ecological stability. Lake Taihu, one China’s largest freshwater lakes, frequently experiences cyanobacterial blooms primarily driven by nutrient over-enrichment changes, posing severe threats to quality, aquatic life, surrounding...
We report a method to prepare hydrophilic poly(dimethylsiloxane) (PDMS) stamps that could transfer patterns of polar molecules homogeneously in soft lithography. In this method, we demonstrated two-step procedure by using mixed gas argon (Ar) and hydrogen (H2)-based microwave plasma pretreatment activate PDMS subsequent acrylonitrile grafting onto PDMS, generating surface with cyano (−CN) group coatings. The exhibited high affinity for wetting acetonitrile, which is conventional solvent DNA...
3-D polyacrylamide gel-based DNA microarray platforms provide a high capacity for nucleic acids immobilization and solution-mimicking environment hybridization. However, several technological bottlenecks still remain in these platforms, such as difficult preparation fluorescent background, which limit their application. In this study, two new approaches have been developed to improve the convenience reduce background after To control polymerization process, solutions containing...
Single nucleotide polymorphisms (SNPs) are important markers which can be used in association studies searching for susceptible genes of complex diseases. High-throughput methods needed SNP genotyping a large number samples. In this study, we applied polyacrylamide gel-based microarray combined with dual-color hybridization study four BDNF autism. All the SNPs both patients and controls could analyzed quickly correctly. Among SNPs, only C270T polymorphism showed significant differences...
Although numerous approaches were proposed for the nucleic acid (NA)-based SARS-CoV-2 detection, nonideal NA desorption efficiency of conventional magnetic beads (MBs) limits their widespread application. In this study, we developed solvent-responsive MBs (called responsive MBs), which, in presence buffers, modulated absorption and capacities by flipping surface -COO-. Relative to other commercial MBs, exhibited similar profiles markedly enhanced profiles. When applied detection complex...
Abstract A novel two‐step process was developed to prepare ssDNA templates for pyrosequencing. First, PCR‐amplified DNA modified with an acrylamide group and monomers were copolymerized in 0.1 M NaOH solution form polyacrylamide gel spots. Second, pyrosequencing prepared by removing electrophoretically unbound complementary strands, unmodified PCR primers, inorganic pyrophosphate (PPi), excess deoxyribonucleotides under alkali conditions. The results show that the 3‐D network has a high...
This paper describes the in situ synthesis of oligonucleotide arrays on glass surfaces by using soft lithography. In this method, based standard phosphoramidite chemistry protocol, coupling was achieved slide being printed with a set polydimethylsiloxane (PDMS) microstamps, which spread nucleoside monomer and tetrazole mixed solution. The elastic characteristic PDMS allowed it to make conformal contact printing coupling. With regard efficiency coupling, hybridization microscope images 20-mer...
Abstract In this paper, a microfilter device with series of pool and dam structures was designed fabricated. To evaluate the efficiency filter, physical models were established to describe behaviors different kind cells in device. our model, both size effect deformability are considered. As cell depends largely on its excess surface area index (ESI), ESI tumor SPC‐A‐1 measured found be as 61.7–81%. From measurements red blood (RBCs) (44%) white (WBCs) (84–137%), we have calculated ultimate...