A5005537356- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatology and Skin Diseases
- Respiratory and Cough-Related Research
- Head and Neck Cancer Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Oral health in cancer treatment
- Respiratory Support and Mechanisms
- Antifungal resistance and susceptibility
- Occupational exposure and asthma
- Insects and Parasite Interactions
- SARS-CoV-2 and COVID-19 Research
- Inhalation and Respiratory Drug Delivery
- Air Quality and Health Impacts
- Advanced Radiotherapy Techniques
- Angiogenesis and VEGF in Cancer
- Contact Dermatitis and Allergies
- Delphi Technique in Research
- Cancer Diagnosis and Treatment
- Biosensors and Analytical Detection
- Pneumocystis jirovecii pneumonia detection and treatment
- Occupational and environmental lung diseases
Guangzhou Medical University
2018-2024
University of Shanghai for Science and Technology
2024
First Affiliated Hospital of Guangzhou Medical University
2018-2024
State Key Laboratory of Respiratory Disease
2018-2024
Jiangxi University of Finance and Economics
2009-2024
University of Łódź
2024
Universidad Complutense de Madrid
2024
Henan University of Technology
2023
National Clinical Research
2021
Weatherford College
2021
Abstract Objectives/Hypothesis: To investigate changes in parotid and submandibular gland volumes of patients with head neck cancer treated postoperative intensity‐modulated radiotherapy (IMRT) or conventional (CRT), to relate the volume different mean radiation therapy (RT) doses glands. Methods: Between May 2007 2008, 82 (oral cavity cancer, 71; oropharynx 11) were surgery RT (IMRT, 40; CRT, 42) at our institution. Every patient underwent four computed tomography (CT) scans: one before RT,...
Allergic diseases are increasing yearly. We aimed to evaluate the difference in allergen sensitization pattern between adults and children southern China by analyzing a large sample size of real-life data, provide evidence for formulating prevention management strategies. Retrospective analysis was conducted on 39,813 serum allergen-specific IgE (sIgE) results collected from January December 2017. Sensitization patterns how these allergens could lead allergic were analyzed respectively. The...
This study aimed to determine the clinical significance of Krebs von den Lungen-6 (KL-6) in patients with COVID-19, so as find a marker high sensitivity, specificity and easy detection evaluate lung injury inflammation COVID-19. Sixty-three COVID-19 43 non-COVID-19 similar phenotypes and/or imaging findings were enrolled test levels KL-6 using chemiluminescent immunoassay. In addition, blood gas, lymphocyte factors tests collected from all participants. The data was finally analyzed...
Dysregulated immune response and abnormal repairment could cause secondary pulmonary fibrosis of varying severity in COVID-19, especially for the elders.The Krebs Von den Lungen-6 (KL-6) as a sensitive marker reflects degree this study will focus on analyzing evaluative efficacy predictive role KL-6 COVID-19 fibrosis.The lasted more than three months included total 289 patients who were divided into moderate (n=226) severe groups (n=63) according to illness.Clinical information such...
Abstract Background Monocyte-derived alveolar macrophages (Mo_AMs) are increasingly recognised as potential pathogenic factors for idiopathic pulmonary fibrosis (IPF). While scRNAseq analysis has proven valuable in the transcriptome profiling of Mo_AMs, integration multi-omics may provide additional dimensions understanding these cellular populations. Methods We performed on 116 scRNAseq, 119 bulkseq and five scATACseq lung tissue samples from IPF. built a large-scale IPF atlas conducted...
Abstract Objectives/Hypothesis: Is the severity of acute oral mucositis in patients who receive postoperative intensity‐modulated radiotherapy (PO‐IMRT) for tongue squamous cell carcinoma (SCC) reduced by sparing mucosa outside planning target volume (PTV)? Study Design: Prospective, randomized trial. Methods: Forty‐eight with SCC received PO‐IMRT at our institution were to two groups: oral‐sparing (OR‐SP) group and oral‐unsparing (OR‐USP) group. For OR‐SP (n = 24), PTV was spared....
Background: Idiopathic interstitial pneumonia (IIP) can induce type II alveolar epithelial cell proliferation and pulmonary basement membrane damage subsequent release of Krebs von den Lungen-6 antigen (KL-6) to the bloodstream. This study investigated diagnostic prognostic value serum KL-6 levels for IIP.
Abstract Understanding the spatial distribution of world cultural heritage in its present-day geographical context is foundation for identification and subsequent protection from key threats vulnerabilities, particularly those arising anthropogenic climate change. To address this challenge, we classified 45 Spanish sites (WCHS) listed UNESCO register (as 2023) according to type, entry date, creation date. establish a basis detailed analysis specific impact change on WCHS, cartographic...
Phadiatop test is a variant of ImmunoCAP assay that covers mixture common aeroallergens. Its diagnostic efficiency in Chinese population remains so far inadequate. We validated testing with assays cohort.Phadiatop was performed for serum samples from 290 asthmatics and 92 healthy controls previously tested "classic" house dust mix (hx2), molds yeasts (mx2), tree pollen (tx4) weed (wx5).Phadiatop positivity shown 46.2% asthmatic patients. Using as the gold standard, concordance rate 91.7%;...
Public health measures during COVID-19 have led to an unprecedented change in social lifestyle which might impact on the allergen sensitization population. We sought explore prevalence patterns of serum inhalant and food allergen-specific IgE (sIgE) total immunoglobulin E (tIgE) level among patients with clinical symptoms suspected allergic diseases before pandemic south China.A large epidemiology study was conducted sIgE tIgE 13,715 China from 2017 2020. Chi-square test Fisher exact were...
Background and objective: The prevalence of asthma is greater than 20% in patients previously diagnosed with COPD. Patients asthma–COPD overlap (ACO) are at risk rapid progression disease severe exacerbations. However, some ACO, a clear distinction from COPD very difficult by using physiological testing techniques. This study aimed to apply novel metabolomic approach identify the metabolites sera order distinguish ACO Methods: In study, blood samples were collected COPD, healthy controls....
While serum periostin and Krebs von den Lungen-6 (KL-6) have been acknowledged as independent markers in idiopathic pulmonary fibrosis (IPF) diagnosis, the clinical combinatory potential of these biomarkers combined with high-resolution computed tomography (HRCT) has yet to be fully explored.
Component-Resolved diagnosis (CRD) can help to establish immunoglobulin E (IgE) sensitization profiles and potential risks determines whether specific IgE is the result of primary or cross-reactivity, especially for those who are polysensitized.We recruited 432 patients with mite-sensitized respiratory allergic diseases study co-sensitization cross-reactivity 17 allergen components in Guangdong Province, China, using CRD method describe association between components.Among patients, serum...
Considering the vulnerability of cultural heritage site from over-tourism, this paper develops a resilience evaluation index system to evaluate for sustainable tourism development. The consists 3 Level I sub-systems, socio-cultural, economic, and ecological ones, 19 II indicators. Using Jiangwan town in China as case, we calculate during 2010–2014 investigate factors explaining variation over time. results indicate that degree inheritance protection level value characteristics are main...
Objective: Bermuda grass pollen is a common inhaled allergen. The aim of this study was to investigate the molecular sensitization patterns major allergens (Bermuda grass, Mugwort and Timothy grass) cross-reactive carbohydrate determinants (CCD) in sensitized patients southern China. Methods: Serum specific IgE (sIgE) levels allergen components (Cyn d 1 Cyn 12), (Phl p 1, Phl 4, 5, 7 (Art v Art 3 4) CCD were detected 78 via EUROBlotMaster system. Results: Compared with CCD-positive patients,...
Abstract Background Few studies have assessed the sensitization of mycotic allergens and Aspergillus fumigatus molecular allergens. This study aimed to investigate relationships A components in allergic bronchopulmonary aspergillosis (ABPA) patients (Af)‐sensitized asthma patients. Methods Serum sIgE levels Penicillium chrysogenum , Cladosporium herbarum Mucor racemosus Candida albicans Alternaria alternata Helminthosporium halodes, allergen (Asp f 1, Asp 2, 3, 4, 6) were measured via...