A5100687689- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Endometrial and Cervical Cancer Treatments
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Antifungal resistance and susceptibility
- Ectopic Pregnancy Diagnosis and Management
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Demographic Trends and Gender Preferences
- Uterine Myomas and Treatments
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Fungal Infections and Studies
- Sperm and Testicular Function
- Streptococcal Infections and Treatments
- Acute Lymphoblastic Leukemia research
- Asthma and respiratory diseases
- Epigenetics and DNA Methylation
- Ovarian cancer diagnosis and treatment
- Molecular Biology Techniques and Applications
- Patient Satisfaction in Healthcare
- HIV Research and Treatment
- Anesthesia and Neurotoxicity Research
Capital Medical University
2000-2025
Anshun University
2025
Mudanjiang Medical University
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
1958-2025
Guang’anmen Hospital
2019-2025
Beijing Obstetrics and Gynecology Hospital
2014-2025
Central South University
2019-2025
Second Xiangya Hospital of Central South University
2019-2025
China West Normal University
2025
Hunan University
2024
Crucial roles of hematologic and immunologic responses in progression coronavirus disease 2019 (COVID-19) remain largely unclear.We sought to address the dynamic changes biomarkers their associations with severity outcomes COVID-19.A retrospective study including 548 patients COVID-19 clarified outcome (discharged or deceased) from a national cohort China was performed. Cross-sectional longitudinal variations were compared different analyzed.On admission, counts lymphocytes, T-cell subsets,...
Cationic amphiphiles have been demonstrated to be superior targeted antibacterial agents whose activity exhibits a close relationship with their alkyl chain substituents. However, systematic and deep investigation of the structure–property is still pending. Meanwhile, cationic risk accumulating in living mammalian cells, which poses great threat biosafety clinical applications. In this study, series amphiphilic aggregation-induced emission luminogens (AIEgens) different chains (TPD-4, TPD-6,...
Metagenomic next-generation sequencing (mNGS) technology has been widely used to diagnose various infections. Based on the most common pathogen profiles, targeted mNGS (tNGS) using multiplex PCR developed detect pathogens with predesigned primers in panel, significantly improving sensitivity and reducing economic burden patients. However, there are few studies summarizing profiles of pulmonary infections immunocompetent immunocompromised patients Jilin Province China large scale.
Contents Vitrification has been shown to decrease the developmental capacity of mammalian oocytes, and this is closely associated with abnormal mRNA expressions vitrified oocytes. However, effect vitrification on transcriptional machinery oocytes examined by RNA sequencing ( ‐seq) yet be defined. In present study, transcriptomes fresh bovine were analysed Smart‐seq2 differently expressed genes determined DE seq2 (an adjusted p ‐value .05 a minimum fold change 2). The differentially s then...
Calf diarrhea is a complex disease that has long been an unsolved problem in the cattle industry. Ningxia at forefront of China scale breeding, and calf gravely restricts development Ningxia's industry.From July 2021 to May 2022, we collected stool samples from calves aged 1-103 days 23 farms five cities Ningxia, performed PCR using specific primers for 15 major reported pathogens diarrhea, including bacteria, viruses, parasites. The effect different seasons on occurrence was explored,...
Magnaporthe oryzae causes rice blast, which poses a significant threat to agriculture. The use of environmentally friendly biological control agents is one the methods used reduce disease incidence. Our study identified isolate WXY53 as Stenotrophomonas geniculata using 16S rDNA and phylogenetic tree analysis. exhibited 53.39 % inhibition rate on growth diameter M. hyphae in dual culture assay. fermentation broth treatment inhibited 97.89 appressoria formation delayed colonization plant...
Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder associated with chronic low-grade inflammation of the ovary. Sodium glucose co-transporter 2 (SGLT2) inhibitors are class antidiabetic drugs that can reduce weight hyperglycemia type diabetes patients. Dapagliflozin highly selective, orally active reversible inhibitor human SGLT2. However, role dapagliflozin in regulating PCOS remains unclear.
Abstract Photosensitizers (PSs) featuring type I reactive oxygen species (ROS) generation and aggregation‐induced emission (AIE) activity offer a promising solution to achieve non‐invasive precise theranostics. However, the reported AIE luminogens (AIEgens) with both characteristic strong type‐I ROS are still scarce structure‐property relationship is unclear. Herein, an innovative acceptor elongation boosted intersystem crossing (AEBIC) design strategy has been proposed endow AIEgen...
Background Early diagnosis and treatment of endometriosis (EM) remain challenging because the lack knowledge about EM development. While oxidative stress (OS) has been associated with EM, link is unclear. We explored OS-related genes (OSRGs) their role in pathogenesis. Material methods combined two ectopic endometrium (EC) eutopic (EU) datasets (GSE11691 GSE25628) into a dataset for analysis. Bioinformatic analyses were used to identify differentially expressed (DEGs), (OSRGs), enriched...
Clinical high-risk (CHR) refers to prodromal phase before schizophrenia onset, characterized by attenuated psychotic symptoms and functional decline. They exhibit similar but milder cognitive impairments, brain abnormalities eye movement change compared with first-episode (FSZ). These alterations may increase vulnerability transitioning the disease. This study explores cognitive-related connectivity (FC) examine differences in progression of schizophrenia. Thirty drug-naive FSZ, 28 CHR, 30...
We report herein the first copper-catalyzed intramolecular borylative cyclization of alkynes with imines, providing an efficient access to alkenyl boronate-containing indolines. Preliminary mechanistic studies suggested a nucleophilic addition process for...
Abstract The emergence of adapted variants the SARS-CoV-2 virus has led to a surge in breakthrough infections worldwide. A recent analysis immune responses people who received inactivated vaccines revealed that individuals with no prior infection have limited resistance Omicron and its sub-lineages, while those previous exhibit significant amount neutralizing antibodies memory B cells. However, specific T-cell remain largely unaffected by mutations, indicating T-cell-mediated cellular...
Polyps from the endometrium is a common cause of abnormal uterine bleeding and sometimes infertility pelvic pain. The objective this study was to measure expression hormone receptors (oestrogen receptor progesterone receptor) in endometrial polyps compare results surrounding tissue. This prospective recruited 53 women prior menopause. showed that oestrogen higher whereas lower than adjacent suggest contribute formation.
Objective To determine the prevalence of virological failure and HIV drug resistance among Chinese patients one year after initiating lamivudine-based first-line antiretroviral treatment. Methods A prospective cohort study with follow-up at 12 months was conducted in four urban sentinel sites China. Antiretroviral naive ≥18 years old were recruited. Blood samples collected for testing CD4 cell count, viral load, (for HIV-1 RNA ≥1000 copies/ml) genotyping resistance. Results total 513...
Neuroinflammation contributes to the occurrence and development of epilepsy. However, several inflammatory factors that are important for facilitating diagnosis reduce or prevent seizures need be further studied. This study is aimed explore serum levels matrix metalloproteinase-9 (MMP-9), interleukin-6 (IL-6), hypersensitive C-reactive protein (hs-CRP), homocysteine (HCY) in epilepsy patients relationship them with Epilepsy (n = 101) Second Xiangya Hospital from January 2017 August 2018 were...