Abstract The extracellular tissue penetrating protozoan parasite Entamoeba histolytica has been known to induce host cell apoptosis. However, the intracellular signaling mechanism used by trigger apoptosis is poorly understood. In this study, we investigated roles of reactive oxygen species (ROS), and MAPKs in Entamoeba-induced human neutrophils. neutrophils incubated with live trophozoites E. revealed a marked increase receptor shedding CD16 as well phosphatidylserine (PS) externalization...

Cryptosporidium parvum is a zoonotic protozoan parasite that causes cryptosporidial enteritis. Numerous outbreaks of cryptosporidiosis have been reported worldwide. transmitted to hosts via consumption contaminated water and food but also by direct contact with soil or infected hosts. The present study investigated farm collected from 34 locations along the western Korean peninsula 24 vegetables purchased local grocery markets in Seoul. vegetable samples were examined real-time polymerase...

Trichostrongylus eggs observed in cellophane-thick smears are difficult, practice, to distinguish from hookworm eggs. In order overcome these limitations, a molecular approach was conducted. A colubriformis adult worm obtained human Laos, which identified morphologically. ITS-1 sequence of this determined, and found be most similar with that T. among the spp. reported so far. Then, compared those species, Ancylostoma duodenale Necator americanus, species-specific oligonucleotide primers were...

BACKGROUND Chronic inflammation has a role in the pathogenesis of benign prostatic hyperplasia (BPH) and prostate cancer. Mast cells have been detected chronic inflammatory infiltrate prostate, it is possible that interaction between epithelial Trichomonas vaginalis influences activity mast stroma. Activated might influence biological functions nearby tissues cells. In this study, we investigated whether reacted with culture supernatant BPH infected T. may induce proliferation stromal...

Cryptosporidium and Cyclospora are well-known coccidian protozoa that can cause waterborne foodborne diarrheal illnesses. There have been a few reports regarding contamination in different vegetables with Cryptosporidium, but no data available the sources of infections Korea. In present study, we collected 6 kinds (perilla leaves, winter-grown cabbages, chives, sprouts, blueberries, cherry tomatoes) from July 2014 to June 2015, investigated by these 2 using multiplex quantitative real-time...

Total of 7,495 children including 3,908 boys and 3,587 girls from a kindergarten 15 primary schools were examined for head lice infestation (HLI). The overall prevalence HLI in this study was found to be 5.8%. Head much more commonly detected than with 11.2% 0.9%, respectively. Sixty-nine treated 1% lindane shampoo alone (group 1), 45 oral trimethoprim/sulfamethoxazole 2), follow-up visits conducted 2 4 weeks later. who still had after the treatment again. At 2-week visit, success rates...

The status of intestinal parasite infections was investigated in two rural villages (Chitrasar, Jerona) Chitwan District, Nepal 1999. Stool examination performed with a total 300 specimens from schoolchildren by formalin-ether sedimentation technique. prevalence rate the surveyed areas 44.0%. Jerona slightly higher than that Chitrasar. female male without statistically significant difference. Entamoeba coli most commonly found protozoan (21.0%) followed Giardia lamblia (13.7%) and others...

Head louse infestation (HLI) is one of the most frequently occurring parasitic diseases in children. This study was conducted to investigate socioeconomic and personal factors influencing HLI Republic Korea. A total 2,210 questionnaires about various related were obtained from children 17 primary schools throughout country. The rate significantly lower who lived together with mother or a family where both parents worked. In addition, whose fathers mothers public officers teachers. However,...

<i>Background:</i> Eosinophils are important cells in host immunity to infections by parasitic worms. Tissue-invasive helminthic parasites have been known induce apoptosis of immune for their successful establishment vivo. We previously found that high doses excretory-secreted products (ESP) secreted lung fluke <i>Paragonimus westermani</i> newly excysted metacercariae (PwNEM), which cause pulmonary or extrapulmonary paragonimiasis human beings, accelerate eosinophil...

Monthly surveys were conducted to investigate the occurrence of chigger mites and seroprevalence scrub typhus among small mammals in Jeollanam-do, southwestern part Korea, from November 2006 through October 2007. Fifty-eight mammals, including 57 Apodemus agrarius (98.3%) 1 Crocidura lasiura (1.7%), captured, a total 4,675 representing 4 genera 8 species collected them. The infestation rate was 69.0%. most predominant A. Leptotrombidium scutellare (54.0%), followed by pallidum (39.4%),...

Background Trichomonas vaginalis ( T. ) is the most common sexually transmitted parasite. It has been detected in prostatic tissue of patients with prostatitis and reported to be associated chronic benign hyperplasia as well prostate cancer. Recently, experimental rodent models induced by pathogen infection have developed. However, there so far no reports caused animals. Here, we investigated whether via rat urethra could cause prostatitis. Methods was injected into through (Wistar rats),...

<i>Background:</i> Eosinophils play an important role in the pathogenesis of allergic diseases. Sensitization and exposure to cockroach allergen have been demonstrated be one major risk factors for development bronchial asthma. However, little is known regarding functional capacity extract antigen activate human eosinophils. <i>Objective:</i> We investigated whether German can eosinophils release cytotoxic inflammatory mediators. <i>Methods:</i> Purified...

Neutrophils are important effector cells against protozoan extracellular parasite Entamoeba histolytica, which causes amoebic colitis and liver abscess in human beings. Apoptotic cell death of neutrophils is an event the resolution inflammation parasite's survival vivo. This study was undertaken to investigate ultrastructural aspects apoptotic during neutrophil triggered by histolytica. Isolated from peripheral blood were incubated with or without live trophozoites E. histolytica examined...

EGb 761®, a standardized extract of Ginkgo biloba leaves, has antioxidant and antiinflammatory properties in experimental models neurodegenerative disorders such as stroke Alzheimer's disease. Tissue plasminogen activator (tPA) acts neuromodulator plays crucial role the manifestation neurotoxicity leading to exaggerated neuronal cell death neurological insult conditions. In this study, we investigated effects 761 on basal glutamate-induced activity expression tPA rat primary cortical...

Cryptosporidium , a protozoan parasite that causes watery diarrhea, is found worldwide and common in areas with low water hygiene. In February 2014, 866 stool samples were collected from the inhabitants of 2 rural White Nile State, Sudan. These assessed by performing modified acid-fast staining, followed examination under light microscope. The overall positive rate oocysts was 13.3%. detected 8.6% obtained living area having purification systems 14.6% not systems. No significant difference...

Microphallus species occur primarily as intestinal parasites of birds and mammals, metacercariae a new belonging to this genus have been discovered from the crab, Macrophthalmus dilatatus, in Republic Korea. The metacercaria fluke was round with 2 thick walls, excysted one had mature genital organs. adult flukes recovered experimentally infected chicks numerous intrauterine eggs, well-developed pars prostatica, widely bifurcating ceca, prominent uterine bulge. After observing internal...

A 29-year-old Korean woman visited the Department of Surgery in MizMedi Hospital with a palpable itching mass on right breast that had existed for past 7 months. She no history to eat either frogs or snakes, but drinking impure water. Sonography revealed serpiginous hypoechoic tubular structure associated partial fat necrosis parenchymal layer and subcutaneous layer. It also oval cystic lesions. At operation, an ivory white opaque ribbon-like worm measured 16.5 cm length 0.5 width was...

There are approximately 20 known species of the genus Cryptosporidium, and among these, 8 infect immunocompetent or immunocompromised humans. C. hominis parvum most commonly Differentiating between them is important for evaluating potential sources infection. We report here development a simple accurate real-time PCR-based restriction fragment length polymorphism (RFLP) method to distinguish hominis. Using CP2 gene as target, we found that both Cryptosporidium yielded 224 bp products. In...

Hymenoptera stings can cause serious injury to humans. We report the clinical findings of 6 cases stings. All patients developed painful erythematous papules at sting sites and had a past history parasitoid wasp sting. This is first wasp, Cephalonomia gallicola, causing human in Korea.