Huihui Zhang

ORCID: 0000-0001-7900-4140
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About
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Research Areas
  • Advanced Sensor and Energy Harvesting Materials
  • Conducting polymers and applications
  • Microbial infections and disease research
  • Immune Response and Inflammation
  • interferon and immune responses
  • Toxin Mechanisms and Immunotoxins
  • Aquaculture disease management and microbiota
  • Tactile and Sensory Interactions
  • Supercapacitor Materials and Fabrication
  • Veterinary medicine and infectious diseases
  • Galectins and Cancer Biology
  • Advanced Thermoelectric Materials and Devices
  • Biomarkers in Disease Mechanisms
  • Viral Infections and Vectors
  • S100 Proteins and Annexins
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Clusterin in disease pathology
  • Natural product bioactivities and synthesis
  • Innovative Energy Harvesting Technologies
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Quantum Dots Synthesis And Properties
  • Streptococcal Infections and Treatments
  • Rabies epidemiology and control
  • Graphene research and applications

Ningbo University
2025

RMIT University
2024

Southwest University
2015-2024

Ministry of Education of the People's Republic of China
2023

Henan Institute of Science and Technology
2009-2023

Tianjin Medical University Cancer Institute and Hospital
2023

Second Affiliated Hospital of Xi'an Jiaotong University
2023

Shandong Agricultural University
2019-2021

South China Agricultural University
2019

Hunan Normal University
2019

Textile-based supercapacitors have recently attracted much attention owing to their great potential as energy storage components in wearable electronics. However, fabrication of a high-performance, fully printed, and ultraflexible supercapacitor based on single textile still remains challenge. Herein, facile, low-cost, textile-compatible method involving screen printing transfer is developed construct all-solid-state silk fabric. The system exhibits high specific capacitance 19.23 mF cm-2 at...

10.1021/acsami.6b11172 article EN ACS Applied Materials & Interfaces 2016-11-07

A repeated coating-reduction approach was developed to directly immobilize graphene nanosheets on silk for high conductivity. The as-prepared highly conductive graphene-coated fabrics (1.5 kΩ sq<sup>−1</sup>) and fibers (3595 S m<sup>−1</sup>) are promising as the functional supporting matrix conducting fabrics/wires in future wearable electronics.

10.1039/c5tc00917k article EN Journal of Materials Chemistry C 2015-01-01

Abstract MAVS is essential for antiviral immunity, but the molecular mechanisms responsible its tight regulation remain poorly understood. Here, we show that NLK inhibits immune response during viral infection by targeting degradation. depletion promotes virus-induced cytokine production and decreases replication, which potently rescued reintroduction of NLK. Moreover, effects increases survival times mice after with VSV. interacts phosphorylates at multiple sites on mitochondria or...

10.1038/s41467-019-11258-x article EN cc-by Nature Communications 2019-07-19

Pasteurella multocida causes a variety of infectious diseases in various species mammals and birds, resulting enormous economic loss to the modern livestock poultry industry. However, mechanism host-pathogen interaction is unclear. Here, we found that l -serine levels were significantly decreased murine lungs infected with P. .

10.1128/iai.00677-19 article EN cc-by Infection and Immunity 2019-10-01

This study aimed to investigate the impact of herpesvirus detection by metagenomic next-generation sequencing (mNGS) bronchoalveolar lavage fluid (BALF) on lower respiratory tract infections (LRTIs) patients' lung microbiome composition and prognosis. We initially enrolled 234 hospitalized patients with LRTIs who underwent BALF mNGS between February 2022 May 2023. The analyzed clinical manifestations pulmonary microbial (HD) non-herpesvirus (non-HD) group. After exclusions, a total 201 were...

10.2147/idr.s484768 article EN cc-by-nc Infection and Drug Resistance 2025-01-01

The development of textile-based devices for human physiological monitoring has attracted tremendous interest in recent years. However, flexible sensing elements based on silk fabrics have not been realized. In this paper, ZnO nanorod arrays are grown situ reduced graphene oxide-coated via a facile electro-deposition method the fabrication silk-fabric-based mechanical devices. data show that well-aligned nanorods with hexagonal wurtzite crystalline structures synthesized conductive fabric...

10.1088/1361-665x/aa782d article EN Smart Materials and Structures 2017-06-08

Abstract Viral immune evasion is crucial to the pathogenesis of hepatitis B virus (HBV) infection. However, role HBV in modulation innate poorly understood. A liver‐specific histone acetyltransferase 1 ( Hat1 ) knockout (KO) mouse model and HAT1 KO cell line were established. Immunohistochemistry staining, Western blot analysis, Southern Northern immunofluorescence assays, enzyme‐linked immunosorbent assay, reverse transcription‐quantitative polymerase chain reaction, chromatin...

10.1002/jmv.28966 article EN Journal of Medical Virology 2023-07-01

Flexible piezoresistive pressure sensors have attracted great attentions due to their critical roles in wearable electronics. It is highly desirable develop a low-cost and facile method for fabricating textile-supported with designed patterns. Herein, we use pre-cut thermoplastic as both mask separator deposit silver nanowires (AgNWs) seal two conductive textiles, respectively, the construction of sensor. The typical sheet resistance AgNWs-coated textile low ∼50 Ω/square. After sealing at...

10.1088/1361-665x/aadb63 article EN Smart Materials and Structures 2018-08-20

Abstract Pasteurella multocida type A (PmA) mainly causes respiratory diseases such as pneumonia in bovines, leading to great economic losses the breeding industry. At present, there is still no effective commercial vaccine against PmA infection. In this study, a mutant strain (PmCQ2Δ4555–4580) with brand-new phenotypes was obtained after serially passaging at 42 °C. Whole genome resequencing and PCR analysis showed that PmCQ2Δ4555–4580 missed six genes, including PmCQ2_004555, PmCQ2_004560,...

10.1186/s12917-024-03948-6 article EN cc-by BMC Veterinary Research 2024-03-09

Introduction. Various plasmid-mediated resistance genes have been reported in Glaesserella parasuis, but little is known about their global distribution features, evolution pattern and spread.Gap Statement. The potential mobilization mechanisms of plasmids G. parasuis poorly explored.Aim. aim the study was to investigate prevalence diversity among isolates, focus on analysis features from parasuis.Method. tested were sequenced using Illumina HiSeq platform conjunction with PCR inverted PCR....

10.1099/jmm.0.001767 article EN Journal of Medical Microbiology 2023-12-19

Tripartite motif-containing 32 (TRIM32) is an E3 ubiquitin ligase with multiple functions. In this study, we amplified TRIM32 gene from the Cherry Valley duck, and its cDNA sequence contained open reading frame of 1,950 bp that encodes 649 amino acids. Duck (duTRIM32) mRNA was expressed in all tissues tested. A series immune-related genes were induced by viral infection, including interferon alfa, IL-1β, retinoic acid–inducible gene-I, Mx, OAS, regulated duTRIM32 expression. DuTRIM32...

10.1016/j.psj.2021.101048 article EN cc-by-nc-nd Poultry Science 2021-02-16

The development of textile-based wearable devices has been a hot research topic in recent years. However, fabric-supported optical switch never reported. Herein, pair interdigital silver electrodes and hydrothermally synthesized Bi2S3 nanowires (NWs) were screen-printed successively onto silk fabric to construct fabric-based flexible switch. device showed irradiation power-dependent light-on currents was able respond blue, green red light. A fast response/recovery time less than 2 ms could...

10.1088/2058-8585/aa63cc article EN Flexible and Printed Electronics 2017-04-24

Galectins play important roles in the host's innate immunity as pattern recognition receptors. In this study, coding sequences of galectin-2 were identified from Cherry Valley ducks. Tissue distribution duck (duGal-2) healthy ducks and infected with avian pathogenic Escherichia coli (APEC) was studied, respectively. The results showed that duGal-2 expression higher gut, kidney, liver tissue, weakly expressed lung brain, ducks; however, level detected being up-regulated after infection APEC....

10.3389/fvets.2020.564088 article EN cc-by Frontiers in Veterinary Science 2020-09-29

Abstract Background : The establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2) is involved in the development multiple malignancies. However, its role hypopharyngeal carcinoma (HPC) progression remains uncharacterized. Methods This study employed bioinformatics to determine ESCO2 expression head and neck squamous cell (HNSC) normal tissues. In vitro proliferation, migration, apoptosis, and/or cycle distribution assays were used function relationship with STAT1. Xenograft...

10.21203/rs.3.rs-2690380/v1 preprint EN cc-by Research Square (Research Square) 2023-03-23

Objective To observe the effect and mechanism of ulinastatin on protecting acute lung injury (ALI) in sepsis rats induced by lipopolysaccharide (LPS). Methods Fifty-two were randomly assigned to group (n = 26) control 26). All given LPS (10 mg/kg) intraperitoneally, injected (100 000 U/kg) 18, 3 h before modeling, received equivalence saline. The levels tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), IL-10 total protein bronchoalveolar lavage fluid (BALF) detected at 0.5,...

10.3877/cma.j.issn.1674-6880.2017.03.003 article EN Chin J Crit Care Med(Electronic Edition) 2017-06-01
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