- Salivary Gland Disorders and Functions
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Trigeminal Neuralgia and Treatments
- Autoimmune Neurological Disorders and Treatments
- Pediatric health and respiratory diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Facial Nerve Paralysis Treatment and Research
- Salivary Gland Tumors Diagnosis and Treatment
- Child Nutrition and Feeding Issues
- Dysphagia Assessment and Management
- Body Image and Dysmorphia Studies
- Temporomandibular Joint Disorders
- Musculoskeletal pain and rehabilitation
- Psychosomatic Disorders and Their Treatments
- Biochemical Acid Research Studies
- Autism Spectrum Disorder Research
- Dental Anxiety and Anesthesia Techniques
- Advanced Neuroimaging Techniques and Applications
- Herpesvirus Infections and Treatments
- Laser Applications in Dentistry and Medicine
- Williams Syndrome Research
- Renal function and acid-base balance
- Pediatric Pain Management Techniques
- Ear and Head Tumors
Tokyo Medical and Dental University
2017-2025
Institute of Science Tokyo
2024-2025
Shanghai Institute for Science of Science
2024
Large language models have been proposed as diagnostic aids across various medical fields, including dentistry. Burning mouth syndrome, characterized by burning sensations in the oral cavity without identifiable cause, poses challenges. This study explores accuracy of large identifying hypothesizing potential limitations. Clinical vignettes 100 synthesized syndrome cases were evaluated using three (ChatGPT-4o, Gemini Advanced 1.5 Pro, and Claude 3.5 Sonnet). Each vignette included patient...
Atypical Odontalgia (AO) is a condition characterized by tooth pain with no apparent cause. Although psychiatric comorbidity seems to be very common, it has rarely been studied. To clarify the influence of on clinical features in patients AO, we retrospectively evaluated their examination records.Clinical and diagnoses 383 AO were investigated reviewing patients' medical records referral letters. Psychiatric categorized according Diagnostic Statistical Manual Mental Disorders, Fifth Edition...
Oral cenesthopathy is characterized by foreign body sensations without medical and dental evidence for them. It thought to be a rare disease in psychiatry, but many patients are visiting clinics seeking treatment remove body. Even though the features of oral might different between psychiatric clinic clinic, there has been no clinic-statistical study from dentists. In this study, we report clinico-statistical with dentistry.This retrospective chart review 606 outpatients Tokyo Medical Dental...
Burning mouth syndrome (BMS) is defined by chronic oral burning sensations without any corresponding abnormalities. Besides amitriptyline, aripiprazole has been reported as a possible medication to manage BMS. However, especially for elderly patients, the adverse events of these medications would be problem. The aim present study was investigate differences in effectiveness and amitriptyline very patients with This retrospective comparative 80 years old older BMS who were initially treated...
Abstract Objective This study aimed (1) to investigate the differences in clinical characteristics of patients between 2 groups, those who have atypical odontalgia ( AO ) only and with burning mouth syndrome BMS ), (2) assess influence psychiatric comorbidity factors on patients' experiences. Method Medical records referral forms visiting Psychosomatic Dentistry Clinic Tokyo Dental University 2013 2016 were reviewed. The final sample included groups 355 patients: n = 272) ‐ ; 83)....
Persistent idiopathic facial pain (PIFP) is the unexplained along territory of trigeminal nerve, including nonorganic tooth called atypical odontalgia (AO). Though PIFP debilitating to patients' livelihood and well-being, its pathophysiology remains poorly understood. Although neurovascular compression (NVC) nerve known be associated with neuralgia (TN), relationship between NVC other orofacial pains has not been fully elucidated.In this study, we investigated differences in characteristics...
There has been considerable research which focused on clarifying the origin of pain in patients with atypical odontalgia (AO), also known as "idiopathic toothache", and identifying effective treatment, but there limited success so far. In this study, we assessed outcomes treatment attempted to identify factors that could account for remission AO.
Dear Editor, Burning mouth syndrome (BMS) is a chronic oral pain without any evident lesions. BMS negatively affects patient's quality of life and generates huge amount medical cost, up to £3000 per year.1 The prevalence rate has been estimated from 1% 3.7% in an adult population.2 It proposed that mainly middle-aged women.3 Nevertheless, the proportion older patients increased gradually psychosomatic dental clinic at Tokyo Medical Dental University. Our specializes medically unexplained...
Objective: To assess the therapeutic dose and safety of amitriptyline outcome following treatment with among older patients burning mouth syndrome (BMS). Methods: 187 consecutive were prescribed as a first-line medication from April 2016 to September 2018 followed-up for >1 month. Patients divided into 3 groups: group 1, 113 aged <65 years; 2, 52 between 65 74 3, 22 75 years or older. The visual analog scale (VAS), Pain Catastrophizing Scale (PCS), Somatic Symptom Scale-8 (SSS-8), Patient...
Objectives: So far, the strong link between neuroticism, chronic pain, and depression has been well-documented in literatures. Some suggested that they might share etiological factors, thus resulting overlapping constructs. However, such effect never tested burning mouth syndrome (BMS) patients, a complex phenomenon influenced by both neuropathic psychopathological factors. We aim to clarify how personality affects individual's pain pain-related experiences. Methods: Two hundred forty-eight...
Abstract Background Phantom bite syndrome (PBS) is characterised by occlusal discomfort without corresponding dental abnormalities. Despite repeated, failed treatments, patients with PBS persist in seeking correction. has been regarded as a mental disorder. However, we have reported that trigger tend to less psychiatric history than those without. Hence, the symptoms of cannot be explained disorder alone, and it unclear if disorders affect sensation. Objective To elucidate pathophysiology...
Background: Burning mouth syndrome (BMS) is a common condition of predominant oral pain without evident cause, that maxillofacial surgeons and otolaryngologists often refer to psychiatrists as somatic symptom disorder. In very rare cases, its typical burning mimics those other diseases in which serious fatal comorbidities may be missed. We encountered three cases squamous cell carcinoma (OSCC) with the first tongue. Case Presentation: 1: A 68-year-old woman had on left lingual margin for 8...
Introduction: Phantom bite syndrome (PBS) is considered as the preoccupation with dental occlusion and continual inability to adapt changed occlusion. These patients constantly demand occlusal corrections undergo extensive excessive treatments. We present three cases PBS-suspected iatrogenic concerns attribution underlying psychosis. Case Presentation: A 70-year-old female demanded orthodontic retreatment complained of tightness cramped sensation teeth in oral cavity, uncomfortable...
Phantom bite syndrome (PBS) is characterized by an uncomfortable sensation during occlusion without any evident abnormality. A recent case-control study with single-photon emission computed tomography (SPECT) using 99mTc-ethyl cysteinate dimer could not find the specific features of regional cerebral blood flow (rCBF), which might be due to heterogeneity PBS. We analyzed brain images PBS corresponding clinical studying subgroups.This contributes elucidating pathophysiology evaluating...
Burning mouth syndrome (BMS) is a chronic oral pain condition characterized by an uncomfortable burning sensation. While the etiology remains unknown, potential underlying pathological factors include neurological components, central sensitization, and psychiatric components. (Russo et al. 2022) The associated with BMS proposed to be classified into nociceptive pain, neuropathic nociplastic recent renewed focus on particularly in basic research. (Shinoda 2022). Seasonal variations birth...