A5070940218- Pain Mechanisms and Treatments
- Salivary Gland Disorders and Functions
- Trigeminal Neuralgia and Treatments
- Dysphagia Assessment and Management
- Botulinum Toxin and Related Neurological Disorders
- Anesthesia and Sedative Agents
- Temporomandibular Joint Disorders
- Olfactory and Sensory Function Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Intensive Care Unit Cognitive Disorders
- Autoimmune Neurological Disorders and Treatments
- Ocular Surface and Contact Lens
- Neuroendocrine regulation and behavior
- Optical Imaging and Spectroscopy Techniques
- Advancements in Transdermal Drug Delivery
- Stress Responses and Cortisol
- Obstructive Sleep Apnea Research
- Head and Neck Cancer Studies
- Circadian rhythm and melatonin
- Pharmacological Effects and Toxicity Studies
- Herpesvirus Infections and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Migraine and Headache Studies
- Glycogen Storage Diseases and Myoclonus
- Musculoskeletal pain and rehabilitation
Kanagawa Dental University
2021-2024
Tokyo Medical and Dental University
2017-2021
Nihon University
2017-2019
Atypical Odontalgia (AO) is a condition characterized by tooth pain with no apparent cause. Although psychiatric comorbidity seems to be very common, it has rarely been studied. To clarify the influence of on clinical features in patients AO, we retrospectively evaluated their examination records.Clinical and diagnoses 383 AO were investigated reviewing patients' medical records referral letters. Psychiatric categorized according Diagnostic Statistical Manual Mental Disorders, Fifth Edition...
Abstract Iatrogenic trigeminal nerve injuries remain a common and complex clinical problem. Satellite glial cell ( SGC ) activation, associated phosphorylation of extracellular signal‐regulated kinase ERK ), neuropeptide expression in the ganglion TG are known to be involved neuropathic pain related injury. However, involvement these molecules orofacial mechanisms is still unknown. Phosphorylation 1/2 lingual crush LNC rats was observed s. To evaluate role neuron– interactions under pain,...
Oral cenesthopathy is characterized by foreign body sensations without medical and dental evidence for them. It thought to be a rare disease in psychiatry, but many patients are visiting clinics seeking treatment remove body. Even though the features of oral might different between psychiatric clinic clinic, there has been no clinic-statistical study from dentists. In this study, we report clinico-statistical with dentistry.This retrospective chart review 606 outpatients Tokyo Medical Dental...
Abstract Objective This study aimed (1) to investigate the differences in clinical characteristics of patients between 2 groups, those who have atypical odontalgia ( AO ) only and with burning mouth syndrome BMS ), (2) assess influence psychiatric comorbidity factors on patients' experiences. Method Medical records referral forms visiting Psychosomatic Dentistry Clinic Tokyo Dental University 2013 2016 were reviewed. The final sample included groups 355 patients: n = 272) ‐ ; 83)....
Persistent idiopathic facial pain (PIFP) is the unexplained along territory of trigeminal nerve, including nonorganic tooth called atypical odontalgia (AO). Though PIFP debilitating to patients' livelihood and well-being, its pathophysiology remains poorly understood. Although neurovascular compression (NVC) nerve known be associated with neuralgia (TN), relationship between NVC other orofacial pains has not been fully elucidated.In this study, we investigated differences in characteristics...
There has been considerable research which focused on clarifying the origin of pain in patients with atypical odontalgia (AO), also known as "idiopathic toothache", and identifying effective treatment, but there limited success so far. In this study, we assessed outcomes treatment attempted to identify factors that could account for remission AO.
Objective: To assess the therapeutic dose and safety of amitriptyline outcome following treatment with among older patients burning mouth syndrome (BMS). Methods: 187 consecutive were prescribed as a first-line medication from April 2016 to September 2018 followed-up for >1 month. Patients divided into 3 groups: group 1, 113 aged <65 years; 2, 52 between 65 74 3, 22 75 years or older. The visual analog scale (VAS), Pain Catastrophizing Scale (PCS), Somatic Symptom Scale-8 (SSS-8), Patient...
Abstract Differences between the effects of intravenous sedation with midazolam (MID) and dexmedetomidine (DEX) on cerebral function elderly patients severe dementia are unclear. This study aimed to compare MID or DEX parameters such as brain waves blood flow (CBF). cross-over analyzed 12 dementia, each patient receiving both drug treatments. Each was administered until a Modified Observer’s Assessment Alertness/Sedation (OAA/S) score 2 reached. Bispectral index (BIS) normalized tissue...
Background: Burning mouth syndrome (BMS) is a common condition of predominant oral pain without evident cause, that maxillofacial surgeons and otolaryngologists often refer to psychiatrists as somatic symptom disorder. In very rare cases, its typical burning mimics those other diseases in which serious fatal comorbidities may be missed. We encountered three cases squamous cell carcinoma (OSCC) with the first tongue. Case Presentation: 1: A 68-year-old woman had on left lingual margin for 8...
<title>Abstract</title> Maintenance of cerebral blood flow (CBF) by maintaining pressure and brain cell activity avoiding hypocapnia is important when administering anesthesia in patients with dementia. This study aimed to evaluate CBF during general elderly severe dementia while their physiological parameters the adequate range. The were anesthetized under a setting range without affecting (mean arterial [MAP] > 50 mmHg; bispectral index [BIS] 20; percutaneous oxygen saturation...
Bright light stimulation of the eye activates trigeminal subnucleus caudalis (Vc) neurons in rats. Sensory information is conveyed to Vc via ganglion (TG). Thus, it likely that TG respond photic and are involved hypersensitivity. However, mechanisms underlying this process unclear. Therefore, hypothesis study bright enhances excitability Expressions calcitonin gene-related peptide (CGRP) neuronal nitric oxide synthase (nNOS) were significantly higher from 5 min 12 h after eye....
When Parkinson's disease (PD) progresses, oral and swallowing functions decline, special care is necessary when performing dental treatments. This study aimed to retrospectively investigate the records of patients with PD analyze general problems establish countermeasures during
The number of patients with oral hypofunction is increasing the aging population, and such increases their risk for dysphagia malnutrition. purpose this study was to measure hardness commercially available confectioneries, select a confectionery suitable masticatory training elderly patients, evaluate effects 1-week on function (occlusal force, ability, tongue pressure).The average values 25 confectioneries were determined. Among them, one softest that felt as "chewable but difficult chew"...
Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies evaluated their effects in detail. Our aim was investigate for the first time effect tablet on drug by endoscopic evaluation healthy subjects. Round tablets (7 , 10 12, 14 mm diameter) were swallowed 15 adults with an endoscope inserted neutral, flex-ion, extension positions. Evaluation difficulty using a numeric rating scale (NRS), presence or absence pharyngeal residue its location,...
Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa in absence underlying causes. BMS patients can pose therapeutic challenge to clinicians. Amitriptyline has been first-line treatment for and known prolong corrected QT interval (QTc) dose dependent manner. However, little about QTc lengthening effect amitriptyline at analgesic dosages. The objective this study was evaluate changes female treated with amitriptyline. We conducted single-center retrospective...