A5056508564- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Supramolecular Chemistry and Complexes
- Crystallography and molecular interactions
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Lanthanide and Transition Metal Complexes
- Nonlinear Optical Materials Studies
- Magnetism in coordination complexes
- Porphyrin and Phthalocyanine Chemistry
- Photochromic and Fluorescence Chemistry
- Synthesis and Properties of Aromatic Compounds
- Nonlinear Optical Materials Research
- Synthesis and Catalytic Reactions
- Molecular spectroscopy and chirality
- Metal complexes synthesis and properties
- Chemical Synthesis and Analysis
- Organophosphorus compounds synthesis
- Supramolecular Self-Assembly in Materials
- Chemical Synthesis and Characterization
- Boron Compounds in Chemistry
- Photochemistry and Electron Transfer Studies
- Fluorine in Organic Chemistry
- Carbon dioxide utilization in catalysis
- Photopolymerization techniques and applications
École Normale Supérieure de Lyon
2013-2024
Centre National de la Recherche Scientifique
2015-2024
Laboratoire de Chimie
2015-2024
Université Claude Bernard Lyon 1
2014-2024
Canadian Nautical Research Society
2017
Lyon College
2016
Institut de Chimie
2015
Institut Charles Sadron
2011
Institut de Chimie et Biochimie Moléculaires et Supramoléculaires
2007
In addition to the already described ligand L4a, two pyclen-based lanthanide chelators, L4b and L4c, bearing specific picolinate two-photon antennas (tailor-made for each targeted metal) one acetate arm arranged in a dissymmetrical manner, have been synthesized, form complete family of luminescent bioprobes: [EuL4a], [SmL4a], [YbL4b], [TbL4c], [DyL4c]. Additionally, symmetrically regioisomer L4a′ was also synthesized as well its [EuL4a′] complex highlight astonishing positive impact...
A series of near-infrared solid-state emitters based on the dicyanoisophorone electron acceptor group was synthesized. The spectroscopic properties were studied by UV−visible absorption spectroscopy and fluorescence analyzed in light single crystal structures obtained X-ray diffraction. This push−pull dipolar fluorophores differing only substituent groups donor end display interesting emission with an ranging from 710 to 790 nm. origin depends nature that influence packing trigger formation...
Introducing an unprecedented nucleating and phasing agent for protein crystallography that presents convenient luminescence properties.
An Yb(<sc>iii</sc>) complex based on a dimethyl cyclen macrocyclic ligand is used as two-photon NIR bioprobe.
Two europium complexes with bis(bipyridine) azamacrocyclic ligands featuring pendant arms or without π-conjugated donor groups are synthesized and fully characterized by theoretical calculations NMR spectroscopy. Their photophysical properties, including two-photon absorption, investigated in water various organic solvents. The nonfunctionalized ligand gives highly water-stable bright luminescence properties but poor absorption cross sections. On the other hand, complex an extended...
Phosphonate cavitands are an emerging class of synthetic receptors for supramolecular sensing. The molecular recognition properties the third-generation tetraphosphonate toward alcohols and water at gas-solid interface have been evaluated by means three complementary techniques compared to those parent mono- diphosphonate cavitands. combined use ESI-MS X-ray crystallography defined precisely host-guest association in terms type, number, strength, geometry interactions. Quartz crystal...
Combining tetraalkyl-ammonium halides and cavitand hosts as catalysts, we achieved the carboxylation of styrene oxide to produce cyclic carbonate from CO2 in good excellent yields. In a first approach presence chloride/tetraphosphonate catalytic systems, an enhanced activity reaction was observed depending on host–guest association. second set experiments, using tetramethylammonium halide/tetraphosphonate complexes obtained corresponding high yields, whereas used alone, salts are inactive...
An original cationic water-soluble cyclen-based Eu(III) complex [EuL1]+ featuring a chromophore-functionalized antenna to increase the two-photon (2P) absorption properties was synthesized. The photophysical were thoroughly studied in various solvents and rationalized with help of theoretical calculations. exhibits an optimized 2P cross section. Finally, microscopy imaging experiments on living T24 human cancer cells highlighted spontaneous internalization biological stability this bioprobe...
We take advantage of the near-resonant enhancement third-order nonlinear response to engineer a two-photon polymerization photoinitiator with optimized efficiency in regard literature benchmarks. study detail its linear and resonant optical properties, particular focus on photoinduced radical generation. Careful choice peripheral substituents enables direct solubilization into mixture commercial multifunctional acrylic monomers, resulting homogeneous photoresist good transparency upon simple...
This work investigates the electron-donating capabilities of two 10-π electron nitrogen bridgehead bicyclic [5,6]-fused ring systems, imidazo[1,2-a]pyridine and imidazo[1,5-a]pyridine rings. Eight compounds with varying positions electron-withdrawing moieties (TCF or DCI) coupled to imidazopyridine were synthesized studied. DCI-containing (Ib–IVb) exhibited a purely dipolar nature broad absorption bands, weak fluorescence, large Stokes shifts, strong solvatochromism. In contrast,...
Well-defined fluorene oligomers (n = 1 to 6) were prepared step by using Suzuki and Yamamoto couplings, while absorption photoluminescence properties evidenced very large dipolar coupling interactions between moieties.
[reaction: see text] A novel class of chiral hemicryptophane hosts has been synthesized in diastereoisomerically pure form, namely, M-(R,R,R)-1a/P-(S,S,S)-1a and M-(S,S,S)-1b/P-(R,R,R)-1b. The C3-symmetrical precursor 9 was prepared, using either (R)- or (S)-glycidyl nosylate, repectively, as the pool reactant subsequently cyclized (trimerized) presence Sc(OTf)3. four stereoisomers were fully characterized displayed two pairs mirror-image CD spectra, which used to determine their absolute...
Two new fluorene derivatized 1,10-phenanthroline ligands and related tris-chelate Ru(II) or Zn(II) coordination complexes have been synthesised. The linear nonlinear (two-photon induced fluorescence) photophysical measurements contributed to highlight the possibility tune absorption spectral range excited lifetime, depending on ligand substitution nature of metal. More significantly, observation two-photon (TPA) associated with long-lived metal-to-ligand charge-transfer (MLCT) states in...
Long-lived excitation: Novel bifluorene-substituted 1,10-phenanthroline-based RuII coordination complexes are presented (see picture). They fulfil several requirements for optimized optical power limiting in the visible-NIR, as they stable, soluble and transparent at low laser fluences. The two-photon absorption of these strongly related to those ligand.
We describe a large-scale synthesis of series helicene-like compounds based on dibenzo[c]acridine fragment by the Friedlander reaction. The includes targeted constrained (closed) derivatives comprising 11 rings that exhibit very intense circularly polarized luminescence (CPL) (glum = 8 × 10-3) contrary to their nonconstrained (open) 10-ring precursors are not CPL active. relationship between structure and chiroptical properties in is discussed with aid quantum-chemical calculations.
We herein report the synthesis and magnetic properties of a Ni(II)-porphyrin tethered to an imidazole ligand through flexible electron-responsive mechanical hinge. The latter is capable undergoing large amplitude fully reversible folding motion under effect electrical stimulation. This redox-triggered movement exploited force axial coordination appended onto square-planar Ni(II) center, resulting in change its spin state from low (S = 0) high 1) proceeding with 80% switching efficiency....
Syntheses and host-guest properties of tetrabridged phosphorylated cavitands in their iiii (4i) configurations are described. The tetraphosphonato 2 3, with the four P=O bonds oriented inwards (4i stereoisomer) were prepared 25% 53% yields respectively, from corresponding resorc[4]arenes, dichloro(phenyl)phosphane oxide base. formation 4i stereoisomers is solvent-dependent attributable to capability an ammonium guest form inclusion complex. Only iiio (3io) stereoisomer 3 was isolated...
A versatile approach is introduced for the synthesis of well-defined, biocompatible conjugates combining two-photon chromophores and hydrophilic multifunctional polymers synthesized by RAFT controlled radical polymerization. As an illustration, two different classes carrying multiple fluorophores (based on anthracene moiety, Anth) or photosensitizers a dibromobenzene DBB) along polymer chain were elaborated bioimaging photodynamic therapy (PDT) applications, respectively. In both cases,...
The synthesis of eight enantiopure molecular cages (four diastereomeric pairs enantiomers) comprising a helically chiral cyclotriveratrylene (CTV) unit, three axially binaphthol linkages, and centrally asymmetric carbon atoms trialkanolamine core, is described. These new constitute novel family hemicryptophanes, which combine classes chirality. Their absolute configuration was successfully assigned by chemical correlation method to overcome the signals overlap in ECD spectra binaphtol CTV...
The third nonlinear optical susceptibility (χ〈3〉) of a new family octupolar molecules with one, two, and three double bonds has been measured at 532 in tetrahydrofuran solutions by the degenerate four-wave mixing (DFWM) method. For comparison, we also analogous dipolar subunits molecules. second hyperpolarizability (γ) for these was deduced. We found that exhibit large second-order values. γ values obtained compounds are approximately 10 times larger than those their corresponding 104 CS2,...
A general two-step preparation of enantiopure N(alpha),N(beta)-orthogonally diprotected alpha-hydrazino acids 1 is developed on a multigram scale. The key reaction the efficient electrophilic amination N-benzyl amino 6 with N-Boc-oxaziridine 7 and accommodates various functional groups encountered in side chains acids. cyclic 2,3,4,5-tetrahydro-3-pyridazine carboxylic acid (piperazic acid) derivatives 2 3 or 3,4-dihydro-3-pyrazolecarboxylate 4 are conveniently prepared from glutamic aspartic...
Herein, we describe our recent expeditious synthesis of dibenzo[c]acridine helicene-like compounds on a large scale in pure enantiomeric form. This flexible allows for variation at several positions the skeleton. Geometrical parameters related to these have been obtained from monocrystal X-ray structure resolution. Additionally, chiroptical recorded, highlighting versatility this family showing example optical rotation 589 nm varying between 135 and 150 deg g–1cm2.
This Article reports a combined experimental and theoretical analysis on the one two-photon absorption properties of novel class organic molecules with π-conjugated backbone based phenylacetylene (JCM874, FD43, FD48) azoaromatic (YB3p25) moieties. Linear optical show that phenylacetylene-based compounds exhibit strong molar absorptivity in UV high fluorescence quantum yield lifetimes approximately 2.0 ns, while azoaromatic-compound has visible region very low yield. The was investigated...