A5061812411- Advanced DC-DC Converters
- Photonic and Optical Devices
- Dermatology and Skin Diseases
- Semiconductor Lasers and Optical Devices
- Wireless Power Transfer Systems
- Advanced Battery Technologies Research
- Multilevel Inverters and Converters
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Autoimmune and Inflammatory Disorders
- Electrochemical sensors and biosensors
- Silicon and Solar Cell Technologies
- Oral Health Pathology and Treatment
- Metal Forming Simulation Techniques
- 3D IC and TSV technologies
- High-Velocity Impact and Material Behavior
- Silicon Nanostructures and Photoluminescence
- Ocular Surface and Contact Lens
- Protein Interaction Studies and Fluorescence Analysis
- Thin-Film Transistor Technologies
- Mechanical and Optical Resonators
- Psoriasis: Treatment and Pathogenesis
- Advanced Photonic Communication Systems
- Glycosylation and Glycoproteins Research
Tokyo Metropolitan University
2013-2024
Osaka Metropolitan University
2022-2024
Osaka University
2023
Nagaoka University
2019-2021
Nagaoka University of Technology
2019-2021
Kyushu University
2013-2014
Yamagata University
2013
Hokkaido University
1983
Kochi Medical School Hospital
1983
Hematoside (2) was originally named for a ganglioside having an equimolar composition of N-glycolylneuraminic acid, galactose, glu-
Abstract Dupilumab is a humanized monoclonal antibody against the interleukin (IL)‐4 receptor alpha chain that inhibits IL‐4 and IL‐13 signalling. It one of systemic treatments for patients with moderate‐to‐severe atopic dermatitis (AD), which provides favourable safety efficacy. We report case psoriasis‐like eruption induced by dupilumab as an adverse effect in patient AD, immediately remitted after switching to baricitinib, JAK1/2. Moreover, skin lesion also simultaneously went into...
BackgroundAtopic dermatitis (AD) is a common chronic eczematous skin disease with severe pruritus. Several new therapeutic agents for AD such as dupilumab, an anti–IL-4Rα antibody, have been developed in recent years. We need to predict which agent the best choice each patient, but this remains difficult.ObjectiveOur aim was examine clinical background factors and baseline biomarkers that could achievement of improved outcomes patients treated dupilumab.MethodsA multicenter, prospective...
To develop precision medicine for atopic dermatitis (AD), it is critical to establish relevant biomarkers. However, the characteristics of various biomarkers have not been fully understood. We previously carried out Biomarkers Predict Clinical Improvement AD in Patients Treated with Dupilumab (B-PAD) study, a comprehensive nationwide study Japan, explore AD.The aim this find associated objective and subjective clinical findings patients moderate-to-severe based on B-PAD identify sensitive...
Abstract The new type of amperometric biosensor described herein, which was fabricated by using a track-etched microporous membrane electrode for glucose detection, comprises prereactor electrode, detector and an immobilized enzyme reactor sandwiched between these electrodes. Because the sample solution flows through this system, interferents are electrolyzed completely at prereactor, positioned upstream reactor. increased current response derives solely from oxidation hydrogen peroxide...
This paper proposes a circuit configuration of LLC converter wide voltage range and high efficiency. The proposed overcomes the narrow gain conventional full-bridge (FB) converters. Owing to switching patterns primary side, two resonant tanks operate in half-bridge FB modes. are designed with different parameters, has six operating These modes enable squeezed frequency span, which is close resonance frequency. control method achieves seamless transition between range. First, principles...
The effects of annealing temperatures on composition and strain in SixGe1-x, obtained by rapid melting growth electrodeposited Ge Si (100) substrate were investigated. Here, a process was performed at 1000, 1050 1100 °C for 1 s. All annealed samples show single crystalline structure orientation. A significant appearance Si-Ge vibration mode peak ~400 cm-1 confirms the existence intermixing due to out-diffusion into region. On process, melts reaches thermal equilibrium short time. Ge/Si...
This paper proposes a dual LLC converter based on six-switch bridge to charge deeply depleted plug-in electric vehicle onboard battery packs. The primary-side switch network comprises an input series or parallel, and two types of transformer-independent modes. Thus, there are four operation In the mode, normalized voltage gains scaled 0.5 therefore, low output can be obtained. addition, in parallel 2.0. These modes operate at resonant frequency switching frequency. Therefore, efficiency...
This paper proposes a single-input dual-output LLC converter that expands the output voltage gain. The proposed circuit has three degrees of freedom (switching frequency and two-phase angles) five operation modes. modes operate in half bridge, full combinations thereof. Each transformers on primary side is connected to bridge series or parallel depending mode. By connecting structure using mode, wide range gain realized. secondary consists an active two loads can be controlled independently...
This paper proposes a circuit configuration of LLC converter that achieves both wide output voltage gain and high efficiency operation. The primary side the proposed is composed six switches to form bridge has two transformers with different parameters. Thus, operation modes, those modes realize range. In addition, resonant tanks allow large magnetizing inductor small inductor, so it possible design reducing for circulating current. validity system verified by built 1.0 kW prototype an input...
Low-temperature annealing (450−700°C) of a-Ge/Sn/c-Ge stacked-structures is examined to achieve high-quality GeSn single-crystals on Ge substrates. Abnormal phenomena, where a GeSn-layer travels toward the surface during annealing, were found. In-depth analyses Sn distribution together with epitaxial-growth clarify mechanisms, i.e., diffusion atoms from a-Ge into molten-Sn, and subsequent release c-Ge substrates cause traveling-zone-melting-growth in self-organizing-manner....
GeSn alloys are attractive materials, with a potentially major impact on next-generation device applications due to the superior electrical properties and transition direct band gap. We investigate growth of by annealing a-Ge/Sn/c-Ge stacked structures. This achieves liquid-phase epitaxial defect-free non-equilibrium Sn concentration (~2%) Ge substrates low-temperature (~600 o C). The in this layers is guaranteed thermal stability for post-annealing at 600 C 30 min.
In this study, an LLC converter that can achieve a wide range of voltage gain and high efficiency for two loads is proposed. The the proposed found to be greater than conventional full-bridge converter. Depending on ON/OFF state five primary switches, offers modes operation. These enable squeezed switching frequency span close resonance frequency. all operation modes, one load controlled by frequency, while other phase-shift angle. control method provides operating seamless transition...
In this paper, to confirm the validity of a new determination method ductile fracture material parameters using bore expanding test, strain in necking area is evaluated qualitatively. Bore test specimen with fine grids on surface used measure area. The grid length by micro scope measured, and radial strain, circumferential equivalent are obtained evaluate evolution. addition qualitative evaluation area, validation proposed confirmed through detail observation neck initiation its evolution...
Abstract not Available.
2012 International Conference on Solid State Devices and Materials,Dependence of chemical structures transition layer at SiO2/Si(100) interface oxidation temperature, annealing in forming gas, oxidizing species
Abstract This paper proposes a dual LLC converter based on six‐switch bridge to charge deeply depleted plug‐in electric vehicle onboard battery packs. The primary‐side switch network comprises an input series or parallel, and two types of transformer‐independent modes. Thus, there are four operation In the mode, normalized voltage gains scaled 0.5; therefore, low output can be obtained. addition, in parallel 2.0. These modes operate at resonant frequency switching frequency. Therefore,...