Patricia Clark

ORCID: 0000-0001-7981-5357
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About
Contact & Profiles
Research Areas
  • Bone health and osteoporosis research
  • Hip and Femur Fractures
  • Vitamin D Research Studies
  • Nutrition and Health in Aging
  • Body Composition Measurement Techniques
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiac, Anesthesia and Surgical Outcomes
  • Musculoskeletal pain and rehabilitation
  • Nutritional Studies and Diet
  • Obesity, Physical Activity, Diet
  • Hip disorders and treatments
  • Rheumatoid Arthritis Research and Therapies
  • Bone Metabolism and Diseases
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Bone fractures and treatments
  • Bone health and treatments
  • Medical Imaging and Analysis
  • Breast Cancer Treatment Studies
  • Vitamin C and Antioxidants Research
  • Child Nutrition and Water Access
  • Childhood Cancer Survivors' Quality of Life
  • Bone and Joint Diseases
  • BRCA gene mutations in cancer
  • Autoimmune and Inflammatory Disorders Research
  • Healthcare cost, quality, practices

Cleveland Clinic Lerner College of Medicine
2025

Universidad Nacional Autónoma de México
2014-2024

Cleveland Clinic
2023-2024

Hospital Infantil de México Federico Gómez
2015-2024

Foundation Center
2024

Favaloro Foundation
2023

The Neurological Institute
2023

NHS Greater Glasgow and Clyde
2023

Ironwood Pharmaceuticals (United States)
2018-2022

Siriraj Hospital
2022

Abstract To develop criteria for the classification of fibromyalgia, we studied 558 consecutive patients: 293 patients with fibromyalgia and 265 control patients. Interviews examinations were performed by trained, blinded assessors. Control group primary matched age sex, limited to disorders that could be confused fibromyalgia. secondary‐concomitant age, concomitant rheumatic disorders. Widespread pain (axial plus upper lower segment left‐ right‐sided pain) was found in 97.6% all 69.1% The...

10.1002/art.1780330203 article EN Arthritis & Rheumatism 1990-02-01

Purpose An estimated 10% of breast and ovarian cancers result from hereditary causes. Current testing guidelines for germ line susceptibility genes in patients with carcinoma were developed to identify carriers BRCA1/ 2 variants have evolved the panel-testing era. We evaluated capability National Comprehensive Cancer Network (NCCN) cancer pathogenic expanded panel testing. Methods institutional review board–approved multicenter prospective registry was initiated 20 community academic sites...

10.1200/jco.18.01631 article EN cc-by-nc-nd Journal of Clinical Oncology 2018-12-07

Abstract Context There are few studies on patients transitioning from denosumab to bisphosphonates. Objective To investigate patient characteristics and changes in bone mineral density (BMD) after alendronate. Design Randomized, open-label, 2-year crossover Denosumab Adherence Preference Satisfaction (DAPS) study (NCT00518531). Setting 25 centers the US Canada. Patients Treatment-naïve postmenopausal women with BMD T-scores −2.0 −4.0. Interventions This post hoc analysis evaluated randomized...

10.1210/clinem/dgz095 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2019-10-26

Objective: To assess the efficacy of hydroxychloroquine, 400 mg daily, for rheumatoid arthritis. Design: Six-month, double-blind, randomized trial. Setting: Ambulatory referral clinic in a Mexico City, Mexico, teaching hospital. Patients: A total 126 patients with early arthritis were randomly assigned to receive mg/d, or placebo; 121 completed study. Results: Hydroxychloroquine showed clinically and statistically significant improvement over placebo joint score (20% greater mean...

10.7326/0003-4819-119-11-199312010-00002 article EN Annals of Internal Medicine 1993-12-01

To identify risk factors associated with obesity in primary school children, a particular focus on those which can be modified. critical periods and growth patterns the development of childhood obesity.871 New Zealand European children were enrolled longitudinal study at birth data collected birth, 1, 3.5 7 years age. Data included weight, height, bioelectrical impedance analysis (BIA), television viewing time 24 h body movement record (actigraphy). The outcome measure was percentage fat...

10.1136/adc.2007.116855 article EN Archives of Disease in Childhood 2007-09-14

Abstract Summary The IOF Epidemiology and Quality of Life Working Group has reviewed the potential role population screening for high hip fracture risk against well-established criteria. report concludes that such an approach should strongly be considered in many health care systems to reduce burden fractures. Introduction long-term osteoporosis management falls on primary most healthcare systems. However, a wide stable treatment gap exists settings; which appears secondary lack awareness...

10.1007/s11657-022-01117-6 article EN cc-by Archives of Osteoporosis 2022-06-28

National Comprehensive Cancer Network guidelines currently recommend germline testing for high-risk genes in selected patients with breast cancer. The clinical utility of recommending all cancer multigene panels is under consideration.To examine the implications universal respect to decision-making.Patients from a previously reported cohort were assessed as in-criteria or out-of-criteria according 2017 and underwent panel between 2018. Patients women men aged 18 90 years, new and/or previous...

10.1001/jamanetworkopen.2022.32787 article EN cc-by-nc-nd JAMA Network Open 2022-09-22
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