A5059040846- Nutrition and Health in Aging
- Frailty in Older Adults
- Cancer survivorship and care
- Advanced Glycation End Products research
- Healthcare Systems and Practices
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Health, Medicine and Society
- Gut microbiota and health
- Cancer therapeutics and mechanisms
- Multiple and Secondary Primary Cancers
- Natural Antidiabetic Agents Studies
- Drug Transport and Resistance Mechanisms
- Physical Activity and Health
- Oral and gingival health research
- Musculoskeletal pain and rehabilitation
- Nutritional Studies and Diet
- Parkinson's Disease Mechanisms and Treatments
- Chronic Lymphocytic Leukemia Research
- Diabetic Foot Ulcer Assessment and Management
- Cardiovascular Health and Disease Prevention
- Multiple Myeloma Research and Treatments
- Health Literacy and Information Accessibility
- Health Promotion and Cardiovascular Prevention
- Protease and Inhibitor Mechanisms
Université de Bordeaux
2013-2024
Centre Hospitalier Universitaire de Bordeaux
2008-2019
Hôpital Cardiologique du Haut-Lévêque
2018-2019
Institut Pasteur de la Guadeloupe
2018
Centre National de la Recherche Scientifique
2015
Institut Bergonié
2004-2013
Centre Hospitalier Agen - Nérac
2013
Hôpital Saint-André
2013
Hôpital Xavier Arnozan
2008-2012
École Nationale Supérieure de Chimie, de Biologie et de Physique
2009
Objective factors for making choices about the treatment of elderly patients with cancer are lacking. This investigation aimed to help physicians select appropriate treatments through identification that predict early death (< 6 months) after initiation chemotherapy treatment.Previously untreated greater than 70 years age who were scheduled first-line various types included. Baseline abbreviated comprehensive geriatric assessment (aCGA), including Mini-Mental State Exam, Timed Get Up and Go...
To determine factors associated with early functional decline during first-line chemotherapy in older patients.Patients age ≥ 70 years receiving for cancer were prospectively considered inclusion across 12 centers France. Functional was defined as a decrease of 0.5 points on the Activities Daily Living (ADL) scale between beginning and second cycle. Factors sought from pretreatment abbreviated comprehensive geriatric assessment, including ADL, Instrumental ADL (IADL), Mini-Nutritional...
SummaryObjectivesTo assess the impact of a personalized diet, with or without addition VSL#3 preparation, on biomarkers inflammation, nutrition, oxidative stress and intestinal microbiota in 62 healthy persons aged 65–85 years.DesignOpen label, randomized, multicenter study. Primary endpoint: High-sensitivity C-reactive protein.SettingCommunity.InterventionsEight week web-based dietary advice (RISTOMED platform) alone supplementation (2 capsules per day). The RISTOMED diet was optimized to...
Objective We tested the effect of dietary advice dedicated to increase intake in older patients at risk for malnutrition during chemotherapy, versus usual care, on one-year mortality. Method conducted a multicentre, open-label interventional, stratified (centre), parallel randomised controlled trial, with 1∶1 ratio, two-year follow-up. Patients were aged 70 years or treated chemotherapy solid tumour and (MNA, Mini Nutritional Assessment 17–23.5). Intervention consisted diet counselling aim...
Purpose The MNA (Mini Nutritional Assessment) is known as a prognosis factor in older population. We analyzed the prognostic value for one-year mortality of items patients with cancer treated chemotherapy basis simplified score. Methods prospective derivation cohort included 606 than 70 years an indication cancers. endpoint to predict was mortality. 18 Full MNA, age, gender, weight loss, origin, TNM, performance status and lymphocyte count were considered construct model. backward...
20568 Background: Treatment-related toxicity risk increases with age and may even lead to toxic death. Detailed evaluation of patient's status becomes mandatory. Comprehensive Geriatric assessment (CGA) is an adequate method evaluate these patients but it probably not necessary all so that a screening tool should be developed. Methods: In prospective multicentric cohort, we studied older than 70 cancer first-line chemotherapy. 364 were evaluated the following CGA tools: MMS, ADL, IADL, MNA,...
Advanced glycation end-products play a role in diabetic vascular complications. Their optical properties allow to estimate their accumulation tissues by measuring the skin autofluorescence (SAF). We searched for an association between SAF and major adverse cardiovascular events (MACE) incidence subjects with Type 1 Diabetes (T1D) during 7 year follow-up. During 2009, 232 T1D were included. measurement, clinical [age, sex, body mass index (BMI), comorbidities] biological data (HbA1C, blood...
9040 Background: When it is time to decide for or against chemotherapy in elderly patients (pts) with cancer, physicians face the difficult balance of risks and benefits. Too much often, decision based on empirical feelings rather than reliable objective factors which are frequently lacking. Yet, pts can benefit from many situations. Method: To help process through identification predicting early death (< 6 months) onset chemotherapy, we performed a prospective accrual older 70 various...
For more than 20 years, and despite the development of new social networks, health forums have remained a privileged place for people to discuss issues. This study investigates motivations participants post message on French online forum (called 'Doctissimo') (Forum Santé - Doctissimo, 2022).Between January 1, 2017 December 31, 2019, all first messages recorded doctissimo ( www.forum.doctissimo.fr ) were selected in their initial format by crawler. The transcripts imported into qualitative...
9012 Background: Actual data on prognostic geriatric factors of health outcomes are lacking. We aimed to examine whether a decrease in autonomy for activities daily living (ADL) after first cycle chemotherapy influences elderly cancer pts prognosis, and determine this LoA from range biological evaluation factors. Methods: Pts> 70 years receiving 1st-line cancers were included multicentre prospective study. A was defined as 0.5 or more points the ADL scale between beginning treatment 2nd...
e19532 Background: Number of elderly people is growing and with them the possibility to develop cancer. Specific cares particularly chemotherapy must allow maintain their quality life. Methods: From 2003 2006, cohort 364 patients older than 70 years cancer was evaluated by oncologist geriatrician before in public private hospitals south-west France. Quality life appreciated QLQ-C30 completion. Standard geriatric evaluation occurred oncologic endpoints were collected . Global life, functions...
Advanced Glycation end-products play a role in diabetic vascular complications. Their optical properties allow to non invasively evaluate their accumulation tissue by measuring skin autofluorescence (SAF). SAF predicts macrovascular complications type 2 diabetes mellitus but it was not demonstrated 1 diabetes. The aim of our study search for an association between and event (MVE) incidence: myocardial infarction, stroke, gangrene or artery revascularization procedures during 7 years...