A5053603005- Genetics, Bioinformatics, and Biomedical Research
- Biomedical and Engineering Education
- Plant Pathogens and Resistance
- School Choice and Performance
- Plant-Microbe Interactions and Immunity
- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Plant Disease Resistance and Genetics
- Urban, Neighborhood, and Segregation Studies
- Early Childhood Education and Development
- Work-Family Balance Challenges
- Parental Involvement in Education
- Plant Pathogens and Fungal Diseases
- Reconstructive Facial Surgery Techniques
- Yeasts and Rust Fungi Studies
- Innovative Teaching and Learning Methods
- Online and Blended Learning
- Experimental Behavioral Economics Studies
- Monoclonal and Polyclonal Antibodies Research
- Nursing Roles and Practices
- Research Data Management Practices
- Gender, Labor, and Family Dynamics
- Poverty, Education, and Child Welfare
- Social and Intergroup Psychology
- Genetics, Aging, and Longevity in Model Organisms
College of Wooster
2009-2023
University of Maryland, College Park
2020
Cleveland State University
1995-2010
Aston University
2009
The Ohio State University
1983-2008
MedStar Health
2002
MedStar Union Memorial Hospital
2002
National Medical Association
1995
Princeton University
1993
Harvard University Press
1988
The genome of Phytophthora infestans, the pathogen that triggered Irish potato famine in nineteenth century, has been sequenced. It remains a devastating pathogen, with late blight destroying crops worth billions dollars each year. Blight is difficult to control, part because it adapts so quickly genetically resistant strains. Comparison two other genomes shows rapid turnover and extensive expansion specific families secreted disease effector proteins, including many genes induced during...
Abstract The Irish potato famine pathogen Phytophthora infestans is predicted to secrete hundreds of effector proteins. To address the challenge assigning biological functions computationally genes, we combined allele mining with high-throughput in planta expression. We developed a library 62 infection-ready P. RXLR clones, obtained using primer pairs corresponding 32 genes and assigned activities several these genes. This approach revealed that 16 examined effectors cause phenotypes when...
Abstract Oomycete plant pathogens deliver effector proteins inside host cells to modulate defense circuitry and enable parasitic colonization. These effectors are defined by a conserved motif, termed RXLR (for Arg, any amino acid, Leu, Arg), that is located downstream of the signal peptide has been implicated in translocation. Because phenotypes extend cells, their genes expected be direct target evolutionary forces drive antagonistic interplay between pathogen host. We used draft genome...
Causal models of adolescents expectations have been based on the assumptions path analysis: Additivy and recursivity. We test these a body 1973 data gathered in Louisville, Kentucky. A second-order interaction race sex with all relationships model which integrated proposed by Duncan, Haller, Portes (1968) Sewell, Ohlendorf (1970) was found, important similarities between white males black females were observed. White showed strongest reciprocal peer effects educational plans...
Although bioinformatics is becoming increasingly central to research in the life sciences, skills and knowledge are not well integrated into undergraduate biology education. This curricular gap prevents students from harnessing full potential of their education, limiting career opportunities slowing innovation. To advance integration sciences a framework core competencies needed. that end, we here report results survey faculty United States about teaching scientists. Responses were received...
Bioinformatics, a discipline that combines aspects of biology, statistics, mathematics, and computer science, is becoming increasingly important for biological research. However, bioinformatics instruction not yet generally integrated into undergraduate life sciences curricula. To understand why we studied how being included in biology education the US by conducting nationwide survey faculty at two- four-year institutions. The asked several open-ended questions probed barriers to...
Abstract The preparation of future scientists, the technical workforce, and informed citizens will require continued transformation to ways we approach STEM teaching learning. Undergraduate education is rapidly emerging as a focus faculty scholarship, but new models for reform need be developed tested accelerate changes in practices. This paper describes flexible, participant-driven, multi-phase, collaborative developing open educational resources (OERs) that leverages linked communities...
This paper presents three basic arguments that draw on data from a sample of forty-two American cities. First, the reveal separate factors-frequency, precipitation conditions, and severity-are important to structure racial disorders. Much earlier work, especially Spilerman, focused only frequency. Hence, in part two we consider disorder frequency, replicating extending Spilerinan's findings. In particular, show certain city-specific differences (nonwhite population size police force size)...
We identified three splicing patterns used to excise the small intron common all transcripts encoded by minute virus of mice. Sequence analysis mice-specific cDNAs indicated that two donor and acceptor splice sites were used: in pattern 1, most frequent, nucleotide 2280 was spliced 2377; 2, nucleotides 2317 2399 joined. Oligonucleotide probes, each specific for one four possible junction sequences, synthesized hybridized viral mRNAs immobilized on nitrocellulose filters. The probes 1 2...
• Double lateral osteotomy has proved to be useful in the management of broad, thick, and heavy maxillary processes. The technique performing two osteotomies indications for its application are described. results obtained from cadaver dissection clinical experience with this discussed. (<i>Arch Otolaryngol</i>103:344-348, 1977)
Subfascial placement of implants was introduced 3 years ago. Collected data reveal very promising short-term and long-term results in comparison with subglandular subpectoral positioned implants. The clinical experiences 69 breast augmentations the subfascial position are reported. indications for this technique proposed. incidence complications is described from compared that other methods. From January 1998 through May 2002, 328 patients underwent periareolar augmentation mammaplasty; 105...
Clones of mouse L cells transfected with a human HLA-B7 gene fragment lacking the 5' segment exon 2 and all upstream sequences express HLA-specific transcripts various lengths. These include species that correspond in size to full-length mRNA. The level these is increased treated interferon. It probable arise as result linkage fragments DNA segments providing transcription initiation or polyadenylylation signals.
Consensus exist among social scientists on the importance of family oring for a multitude individual outcomes, but complete understanding mechanisms producing these parental-filial linkages is lacking. This paper explores interpretation connection between parental socioeconomic origins and adolescent schooling experiences using Melvin Kohn's concept self-direction/conformity values. Using data from public school students in Louisville, Kentucky, their mothers, we examine role maternal values...
Research on how norms about equity and equality affect social exchange has stressed the importance of actors' status focused almost exclusively allocation decisions. This research proposes tests two revisions in theory: (1) Exchanges guided mainly by norm emphasize solidarity; (2) decisions procedure, not just allocation. An experiment with pairs equity-oriented strangers equality-oriented friends showed that increased their competition response to a perceived inequality, but did not. On an...
Socialization by mothers, a key determinant of daughters' work orientation, has generally been thought to operate via positive role-modeling. But socialization also occurs through negative modeling, normative influence, and conditional modeling. Using sample Louisville high school senior girls their we tested whether the differential presence these processes helps explain why higher percentages black than white women work. Other modeling for whose mothers hold blue-collar jobs, both groups...
Representations of voluntary childlessness — the declaration by an individual that he or she does not wish to bear raise children were studied in 116 articles published British national newspapers period 1990—2008. Media framing analysis was used examine broad patterns topic, identifying four frames: as rights issue, a form resistance, social trend, and personal decision. These frames, it is argued, may act potential ‘scripts’ for newspaper readers who are debating decision start family.
While it is essential for life science students to be trained in modern techniques and approaches, rapidly developing, interdisciplinary fields such as bioinformatics present distinct challenges undergraduate educators. In particular, many educators lack training new fields, high-quality teaching learning materials may sparse. To address this challenge with respect bioinformatics, the Network Integration of Bioinformatics into Life Science Education (NIBLSE), partnership Quantitative...
Benign papular eruption on the left leg of a 72-year-old diabetic man developed into rapidly spreading necrotizing fasciitis despite antimicrobial therapy and surgical debridements. This led to eventual amputation control infection. The etiological agent was Staphylococcus aureus isolate harboring enterotoxin gene cluster seg, sei, sem, sen, seo but lacked all common toxin genes, including Panton-Valentine leukocidin.
This study investigated student perceptions of using instant messaging software for online interactive chapter discussions in a graduate teacher educational technology course. The criterion instrum...
Conclusions from the 1981 public-private schooling report of Coleman, Hoffer and Kilgore are for most part unsupported by data National Longitudinal Surveys Youth Labor Market Behavior. With exception a slight gain in verbal achieveme'nt Hispanics private schools, vocational achievement white students public sectors do not differ amount learning produced, once appropriate background curriculum controls introduced. Attending Catholic school does slightly raise expected educational...
We describe our characterization of kin-15 and kin-16, a tandem pair homologous Caenorhabditis elegans genes encoding transmembrane protein tyrosine kinases (PTKs) with an unusual structure: the predicted extracellular domain each putative gene product is only about 50 amino acids, there are no potential autophosphorylation sites in C-terminal domain. Using lacZ fusions, we found that kin-16 both appear to be expressed during postembryonic development large hypodermal syncytium (hyp7) around...