Reina Tonegawa‐Kuji

ORCID: 0000-0001-7998-939X
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Syncope and Autonomic Disorders
  • Sarcoidosis and Beryllium Toxicity Research
  • Cardiovascular Function and Risk Factors
  • Cardiac Structural Anomalies and Repair
  • Burn Injury Management and Outcomes
  • Congenital Heart Disease Studies
  • Venous Thromboembolism Diagnosis and Management
  • Cardiovascular Effects of Exercise
  • Advanced MRI Techniques and Applications
  • Viral Infections and Immunology Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Pulmonary Hypertension Research and Treatments
  • Cholinesterase and Neurodegenerative Diseases
  • Cardiomyopathy and Myosin Studies
  • Alzheimer's disease research and treatments
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Coronary Artery Anomalies
  • Blood Pressure and Hypertension Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Heart Failure Treatment and Management

National Cerebral and Cardiovascular Center
2020-2025

Cleveland Clinic
2024-2025

Cleveland Clinic Lerner College of Medicine
2024-2025

Kumamoto University
2020-2022

Saitama Prefecture
2016-2018

The University of Tokyo
2012

Abstract Background and Aims Few recent large-scale studies have evaluated the risks benefits of continuing oral anticoagulant (OAC) therapy after catheter ablation (CA) for atrial fibrillation (AF). This study status continuation OAC association between thromboembolic bleeding events according to CHADS2 score. Methods retrospective included data from Japanese nationwide administrative claims database patients who underwent CA AF April 2014 March 2021. Patients without recurrence assessed by...

10.1093/eurheartj/ehad798 article EN cc-by-nc European Heart Journal 2023-12-20

Abstract Background Cancer-therapy related cardiac dysfunction (CTRCD) remains a significant cause of morbidity and mortality in cancer survivors. In this study, we aimed to identify differential plasma proteins metabolites associated with left ventricular (LVD) patients. Methods We analyzed data from 50 patients referred the Cleveland Clinic Cardio-Oncology Center for echocardiograph assessment, integrating electronic health records, proteomic, metabolomic profiles. LVD was defined as an...

10.1186/s40959-025-00309-6 article EN cc-by Cardio-Oncology 2025-02-13

The Japanese Catheter Ablation (J-AB) registry, started in August 2017, is a voluntary, nationwide, multicenter, prospective, observational performed by the Heart Rhythm Society (JHRS) collaboration with National Cerebral and Cardiovascular Center using Research Electronic Data Capture system. purpose of this registry to collect details target arrhythmias, ablation procedures, including type outcomes, acute complications real-world settings. During year 2021, we have collected total 89 609...

10.1002/joa3.12931 article EN cc-by-nc-nd Journal of Arrhythmia 2023-09-25

Abstract Introduction Infection is one of the most important complications associated with cardiac implantable electronic device (CIED) therapy. The number reports comparing outcomes transvenous lead extraction (TLE), surgical extraction, and conservative treatment for CIED infections using a real‐world database limited. This study investigated association between strategies their outcomes. Methods We performed retrospective analysis 3605 patients admitted to 681 hospitals nationwide...

10.1111/pace.14789 article EN Pacing and Clinical Electrophysiology 2023-07-23

To identify differences in patient characteristics, clinical practice and outcomes of cardiac implantable electronic device (CIED) therapy between Japan the USA. A cross-sectional study. Nationally representative administrative databases from USA containing hospitalisations with first-time implantations pacemakers, cardioverter-defibrillators (ICD) cardiac-resynchronisation or without defibrillators (CRTP/CRTD). Patients hospitalised CIEDs. In-hospital mortality, in-hospital complication...

10.1136/bmjopen-2022-068124 article EN cc-by-nc BMJ Open 2023-01-01

Objective We investigated the diagnostic performance of semi-quantitative hyperintensity on T2-weighted short-tau-inversion-recovery black-blood (T2W-STIR-BB) images in identifying active cardiac sarcoidosis (CS) patients, and compared it with that 18 F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Methods This retrospective study included 40 steroid-naive patients (age 63.1±12.9 years, 20 men) diagnosed CS who underwent both MRI FDG-PET imaging. Active cases were defined as...

10.1136/openhrt-2021-001728 article EN cc-by-nc Open Heart 2021-09-01

BackgroundImplantable cardiac monitors (ICMs) help investigate the cause of unexplained syncope, but probability and predictors needing a pacing device thereafter remain unclear.MethodsWe retrospectively analyzed data patients who received ICM insertion for syncope with suspected arrhythmic etiology. The were obtained from nationwide database between April 1, 2012 March 31, 2020. Multivariable mixed-effects survival analysis was performed to identify implantation (PDI), risk score model...

10.1016/j.cjco.2022.12.007 article EN cc-by-nc-nd CJC Open 2022-12-23

Abstract Background The current status of wearable cardiovascular defibrillators (WCD) use in Japan is unclear. Methods Using a nationwide claims database Japan, we assessed characteristics patients using WCD and factors influencing subsequent implantable cardioverter‐defibrillator (ICD) implantation. Results In 1049 cases, those with prior cardiopulmonary arrest (CPA) or ventricular arrhythmia, cardiomyopathy, device‐related issues were more likely to require permanent ICDs, whereas females...

10.1002/joa3.13113 article EN cc-by Journal of Arrhythmia 2024-07-14

Introduction: Translating human genetic findings, such as genome-wide association studies (GWAS) to pathobiology and the discovery of therapeutic target remains a major challenge for Atrial Fibrillation (AF). We previously published network topology-based deep learning framework identify disease-associated genes (NETTAG). Hypothesis: By using framework, we can efficiently AF risk genes, druggable targets, candidates repurposable drugs. Aims: To potential related drug our framework. Methods:...

10.1161/circ.150.suppl_1.4118735 article EN Circulation 2024-11-12
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