A5101885837- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Ion channel regulation and function
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Neurological disorders and treatments
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Syncope and Autonomic Disorders
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Cerebrospinal fluid and hydrocephalus
- Cerebrovascular and Carotid Artery Diseases
- Fetal and Pediatric Neurological Disorders
- Heart Failure Treatment and Management
- Sports injuries and prevention
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Congenital Heart Disease Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
Hokkaido University
2025
National Cerebral and Cardiovascular Center
2015-2024
Kumamoto University
2019-2024
University of Rochester Medical Center
2019
Kyoto Medical Center
2019
Osaka Police Hospital
2010-2014
The University of Tokyo
2005
Tokyo Medical and Dental University
1992
Juntendo University
1985-1991
Epicardial unipolar mapping has not been thoroughly investigated in Brugada syndrome (BrS). To examine the characteristics of epicardial potentials BrS and investigate differences from overt cardiomyopathy. was performed 8 patients with 6 We J-wave amplitudes using recordings at delayed potential (DP) sites via bipolar recordings. The repolarization time (RT) around DP recording measured, maximum dispersion RT divided by distance defined as index (RTDI). baseline revealed significantly...
Risk stratification in patients with Brugada syndrome for primary prevention of sudden cardiac death is still an unsettled issue. A recent consensus statement suggested the indication implantable cardioverter defibrillator (ICD) depending on clinical risk factors present (spontaneous type 1 electrocardiogram (ECG) [Sp1], history syncope [syncope], and ventricular fibrillation during programmed electrical stimulation [PES+]). The ICD majority patients, however, remains unclear.A total 218...
<h3>Background</h3> Pregnancy is one of the biggest concerns for women with long QT syndrome (LQTS). <h3>Objectives</h3> This study investigated pregnancy-related arrhythmic risk and efficacy safety β-blocker therapy lethal ventricular arrhythmias in pregnant LQTS (LQT-P) their babies. <h3>Methods</h3> 136 pregnancies 76 LQT-P (29±5 years old; 22 LQT1, 36 LQT2, LQT3, 17 genotype-unknown) were enrolled. We retrospectively analysed clinical electrophysiological characteristics pregnancy...
Background Aging is one of the major concerns and determinants indications for catheter ablation (CA) atrial fibrillation. This study aimed to assess safety CA in older patients with fibrillation undergoing CA. Methods Results The JROAD-DPC (Japanese Registry All Cardiac Vascular Diseases-Diagnosis Procedure Combination) a nationwide claims database using data from Japanese Diagnosis Combination/Per Diem Payment System. Among 6 632 484 records found between April 2012 March 2018 1058...
Background/Aim: Hepatectomy with extrahepatic bile duct resection (Hx+EBDR), pancreaticoduodenectomy (PD), and occasionally hepatopancreaticoduodenectomy (HPD) are required for the treatment of advanced gallbladder cancer (GBC). This study aimed to clarify clinical value these extended surgeries GBC. Patients Methods: We retrospectively reviewed medical records patients who underwent curative (Surg-G, n=59), their survival rates were compared those unresectable GBC chemotherapy (CTx-G,...
Landiolol effectively controls rapid heart rate in atrial fibrillation or flutter (AF/AFL) patients with left ventricular (LV) dysfunction. However, predicting landiolol Responders and Non-Responders who will experience adverse effects remains a challenge. The aim of this study was to clarify the potential applicability for AF/AFL refractory tachyarrhythmias (VTs) failure. A total 39 response ≥120 bpm 12 VTs were retrospectively enrolled. defined as whose suppressed less than 110 decreased...
Background: Pulmonary vein isolation (PVI) is a cornerstone of catheter ablation in patients with paroxysmal atrial fibrillation, and balloon-based has been recently performed worldwide. The second-generation cryoballoon (CB2) proven to be highly effective achieving freedom from fibrillation. However, there are some debatable questions, including the ideal number freeze cycles. Methods: AD-Balloon study (Multicenter Study Validity Additional Freeze Cycles for Cryoballoon Ablation) was...
Human cardiac ryanodine receptor 2 (RYR2) shows autosomal-dominant inheritance in catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1); however, de novo variants have been observed sporadic cases. Here, we investigated CPVT1-related RYR2 variant and its clinical significance between familial We enrolled 82 independent CPVT1 probands (median age: 10.0 (7.0-13.0) years; 45 male) carrying the whose biological origin could be confirmed by parental genetic analysis: assured...
A low ratio of serum eicosapentaenoic acid to arachidonic (EPA/AA) has been associated with cardiovascular events. Higher-grade yellow color coronary plaques are higher plaque vulnerability and thrombogenic potential. Therefore, the association between EPA/AA grade was examined.Consecutive patients (n=54) who underwent percutaneous intervention were enrolled in this study. The examined on admission. All an angioscopic examination culprit vessel examine (0, white; 1, slight yellow; 2, 3,...
<h3>Importance</h3> Long QT syndrome (LQTS) is caused by several ion channel genes, yet risk of arrhythmic events not determined solely the responsible gene pathogenic variants. Female sex after adolescence associated with a higher in individuals congenital LQTS, but association between and genotype-based LQTS still unclear. <h3>Objective</h3> To examine location LQTS-related variant as it pertains to life-threatening arrhythmias. <h3>Design, Setting, Participants</h3> This retrospective...
Background: Little is known regarding the impact of socioeconomic factors on use evidence-based therapies and outcomes in patients with heart failure reduced ejection fraction across Asia. Methods: We investigated association both patient-level (household income, education levels) country-level (regional income level by World Bank classification, disparity Gini index) indicators guideline-directed therapy clinical (composite 1-year mortality or HF hospitalization, quality life) prospective...
Published reports regarding inferolateral early repolarization (ER) syndrome (ERS) before 2013 possibly included patients with Brugada-pattern electrocardiogram (BrP-ECG) recorded only in the high intercostal spaces (HICS). We investigated significance of HICS ECG recording ERS patients. Fifty-six showing ER standard and spontaneous ventricular fibrillation (VF) not linked to structural heart disease underwent drug provocation tests by sodium channel blockade right precordial (V1–V3) 2nd–4th...