A5072640297- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Coronary Artery Anomalies
- Ion channel regulation and function
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Issues in Pregnancy
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Mechanical Circulatory Support Devices
- Receptor Mechanisms and Signaling
- Kawasaki Disease and Coronary Complications
- ECG Monitoring and Analysis
- Vascular anomalies and interventions
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Heart Failure Treatment and Management
- Renal and Vascular Pathologies
Seirei Hamamatsu General Hospital
2022-2025
Waseda University
2024
Stony Brook School
2024
Stony Brook University
2024
Shizuoka General Hospital
2020-2023
Shizuoka Children's Hospital
2019-2023
Kokura Memorial Hospital
2023
Tenri Hospital
2017-2022
Nara Medical University
2020-2022
University of Pennsylvania
2022
1 Current status of non‐pharmacotherapies in Japan Pacemaker treatment for bradyarrhythmia was first approved national health insurance coverage Japan 1974, and its use rapidly became widespread thereafter. Approximately 40 years later, 2017, the number patients treated with this technology has increased to 60 137 (41 895 new cases approximately 18 242 replacements). 5 Capsule‐shaped leadless pacemaker also available 2016, is being established as a option. Non‐pharmacological...
The original guideline for non-pharmacological treatments (cardiac implantable electronic device, catheter ablation, and arrhythmia surgery) of arrhythmias (Japanese Circulation Society [JCS] Guideline on Non-pharmacotherapy Cardiac Arrhythmias) was first published in 2001, there have been two revisions thereafter (2006 2011). “JCS Indications Procedures Catheter Ablation” 2012 to cover the rapid development expansion ablation techniques. Advances treatment further accelerated since then,...
The prognostic value of cardiopulmonary exercise testing (CPX) for mortality risk remains controversial in Fontan patients.Our goal the present study was to clarify major CPX variables and factors determining capacity a large cohort patients.Since 1990, heart rate (HR), oxygen uptake (VO2 ), ventilatory equivalent carbon dioxide production (VE/VCO2 ) at peak were determined 335 patients (18 ± 5 years old), compared with clinical profile events.When 209 controls, HR (148 24 bpm), VO2 (27 7...
In view of the increasing complexity both cardiovascular implantable electronic devices (CIEDs) and patients in current era, practice guidelines, by necessity, have become increasingly specific. This document is an expert consensus statement that has been developed to update further delineate indications management CIEDs pediatric patients, defined as ≤21 years age, intended focus primarily on for setting specific disease categories. The also highlights variations between previously...
Determinant risk factors for developing protein losing enteropathy (PLE), including haemodynamics, remain unclear in patients after the Fontan operation.Our purpose was to characterize serial PLE haemodynamics before and onset determine based on cardiac catheterization-based analysis.Of 354 survivors who had undergone postoperative catheterizations, we experienced 26 during follow-up. Non-left ventricular morphology systemic ventricle, functional one-lung pulmonary circulation an early high...
<h3>Background</h3> Pregnancy is one of the biggest concerns for women with long QT syndrome (LQTS). <h3>Objectives</h3> This study investigated pregnancy-related arrhythmic risk and efficacy safety β-blocker therapy lethal ventricular arrhythmias in pregnant LQTS (LQT-P) their babies. <h3>Methods</h3> 136 pregnancies 76 LQT-P (29±5 years old; 22 LQT1, 36 LQT2, LQT3, 17 genotype-unknown) were enrolled. We retrospectively analysed clinical electrophysiological characteristics pregnancy...
Abstract In view of the increasing complexity both cardiovascular implantable electronic devices (CIEDs) and patients in current era, practice guidelines, by necessity, have become increasingly specific. This document is an expert consensus statement that has been developed to update further delineate indications management CIEDs pediatric patients, defined as ≤21 years age, intended focus primarily on for setting specific disease categories. The also highlights variations between previously...
In view of the increasing complexity both cardiovascular implantable electronic devices (CIEDs) and patients in current era, practice guidelines, by necessity, have become increasingly specific. This document is an expert consensus statement that has been developed to update further delineate indications management CIEDs pediatric patients, defined as ≤21 years age, intended focus primarily on for setting specific disease categories. The also highlights variations between previously...
Maternal New York Heart Association (NYHA) class is associated with pregnancy outcome in women congenital heart disease (WCHD), but objective predictive criteria of exercise capacity have not been established.A total 33 WCHD (age, 28 ± 5 years; NYHA class, 1.3 0.6) who had undergone cardiopulmonary testing (CPX) 1.8 2.2 years before their delivery were retrospectively identified. Maternal, cardiac, and neonatal events occurred 8 (24%), 12 (36%), 14 (42%), respectively. All CPX parameters...
The long-term prognosis of cardiac ryanodine receptor (RyR2) positive catecholaminergic polymorphic ventricular tachycardia (CPVT) patients after initiation medical therapy has not been well investigated. This study aimed to assess the recurrence fatal event inRyR2-positive CPVT patients.Thirty-fourRyR2-positive with a history events were enrolled. All had treatment initiated first symptom or diagnosis. Exercise stress tests (ESTs) performed evaluate efficacy therapy. Even therapy, high-risk...
Background— Inherited cardiac arrhythmia susceptibility contributes to sudden death during infancy and may contribute perinatal neonatal mortality, but the molecular basis of this risk relationship genetic disorders presenting later in life is unclear. We studied functional pharmacological properties a novel de novo sodium channel gene ( SCN5A ) mutation associated with an extremely severe presentation long-QT syndrome unrelated probands different ethnicity. Methods Results— Two subjects...
Background: The serial hemodynamics and predictors of long-term, good Fontan survivors remain unknown. Methods Results: Two hundred one patients who had undergone a operation before September 1998 were reviewed to compare their long-term clinical status with hemodynamics. During mean follow-up 18.7 years, 47 (30.1%) the 156 no events that required an unscheduled hospitalization. Of those, 18 exhibited respective values central venous pressure (CVP, mmHg), cardiac index (CI, L·min-1·m2),...
This study aims to assess the impact of pacing sites on effectiveness cardiac resynchronization therapy (CRT) in systemic right ventricle (sRV) patients with/without a rudimentary left (rLV). We evaluated 13 procedures 11 sRV with wide QRS (>150 ms). Based digitalization results ventriculography, long-axis dyssynchrony (LD) was defined as extremely delayed ventricular (RV) outflow tract movement: ≥100 ms delay from RV apical contraction, and short-axis (SD) paradoxical contraction between...
Background:Cardiac resynchronization therapy (CRT) can result in functional improvement and reduced mortality patients with medically refractory heart failure. Although CRT is reportedly effective congenital disease (CHD), it still controversial who have systemic right ventricle.Methods Results:Twenty CHD treated since 2006 were divided into 3 groups based on ventricular (sysV) morphology (7 left ventricle [sLV], 7 [sRV], 6 unbalanced 2 ventricles as a single-ventricular physiology [sBV])....