A5070179989- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Neurological disorders and treatments
- ECG Monitoring and Analysis
- Diabetes Treatment and Management
- Cardiovascular Effects of Exercise
- Diabetes Management and Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and exercise physiology
- Cerebrovascular and Carotid Artery Diseases
- Heart Failure Treatment and Management
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ion channel regulation and function
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cardiac Fibrosis and Remodeling
- Long-Term Effects of COVID-19
- Cardiac Imaging and Diagnostics
- Dermatology and Skin Diseases
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroscience and Neural Engineering
Shizuoka Medical Center
2014-2024
Shimizu (Japan)
2013-2023
National Hospital Organization
2009-2022
Kinetic Art & Technology (United States)
2017
Nippon Medical School
2005-2010
Abstract Background Protection from lethal ventricular arrhythmias leading to sudden cardiac death (SCD) is a crucial challenge after acute myocardial infarction (AMI). Cardiac sympathetic and parasympathetic activity can be noninvasively assessed using heart rate variability (HRV) turbulence (HRT). The EMBODY trial was designed determine whether the Sodium–glucose cotransporter 2 (SGLT2) inhibitor improves nerve activity. Methods This prospective, multicenter, randomized, double-blind,...
1 Current status of non‐pharmacotherapies in Japan Pacemaker treatment for bradyarrhythmia was first approved national health insurance coverage Japan 1974, and its use rapidly became widespread thereafter. Approximately 40 years later, 2017, the number patients treated with this technology has increased to 60 137 (41 895 new cases approximately 18 242 replacements). 5 Capsule‐shaped leadless pacemaker also available 2016, is being established as a option. Non‐pharmacological...
The original guideline for non-pharmacological treatments (cardiac implantable electronic device, catheter ablation, and arrhythmia surgery) of arrhythmias (Japanese Circulation Society [JCS] Guideline on Non-pharmacotherapy Cardiac Arrhythmias) was first published in 2001, there have been two revisions thereafter (2006 2011). “JCS Indications Procedures Catheter Ablation” 2012 to cover the rapid development expansion ablation techniques. Advances treatment further accelerated since then,...
Aims The efficacy and safety of cardiac rehabilitation for patients with persistent atrial fibrillation who restored sinus rhythm after catheter ablation remains unclear. aim the present study was to evaluate effects on exercise capacity, inflammatory status, function, in had ablation. Methods In this randomized controlled study, 61 treated (male, 80%; mean age, 66 ± 9 years) were analyzed. Thirty underwent (rehabilitation group), whereas remaining 31 received usual care (usual group). group...
Endurance training improves oxidative stress and vascular endothelial dysfunction in patients with chronic heart failure (CHF). However, CHF an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy-defibrillator (CRT-D) often avoid endurance for fear of ICD shock. Recent studies have reported that stretching exercises enhance antioxidant activity improve responses. Therefore, we aimed to assess the effects 4 weeks on function CRT-D.Fifty sedentary (78% males; mean...
The antiarrhythmic effect of triple-site biventricular stimulation (Tri-V) is poorly understood. This study aims to evaluate the cardiac resynchronization therapy (CRT) on ventricular arrhythmia (VA) with Tri-V using a single right (RV) and double left (LV) lead. Over period 3.5 years, 58 consecutive patients New York Heart Association class II–IV heart failure, an LV ejection fraction ≤0.35, QRS interval ≥120 ms were enrolled. Acute haemodynamic responses dual-site (Bi-V) evaluated by...
Abstract Background The efficacy of prophylactic coronary revascularization with percutaneous intervention (PCI) or artery bypass graft (CABG) surgery in patients abdominal aortic aneurysm (AAA) scheduled for open repair remains controversial. Hypothesis Concomitant disease (CAD) no inducible ischemia can be medically treated AAA undergoing as long the existence CAD is recognized. Method A retrospective analysis acute and long‐term outcomes was performed 122 who underwent arteriography (CAG)...
The Brugada‐type electrocardiogram (ECG) is characterized by ST‐segment elevation in the right precordial ECG leads and has been reported to have potential of sudden death. Right ventricular outflow tract supplied from conus branch coronary artery (CB) considered as anatomopathologic substrate Brugada syndrome. We experienced two asymptomatic patients with a saddleback who exhibited dynamic conversion coved type following fibrillation/ventricular tachycardia (VT/VF) episode when myocardial...
A 64-year-old man with repetitive gastrointestinal bleeding was admitted to our hospital. Colonic artery angiography revealed angiodysplasia as the site, and echocardiography showed aortic valve stenosis. decrease in high molecular weight von Willebrand factor multimers, which are known play an important role hemostasis, observed, Heyde syndrome diagnosed. We selected colectomy instead of replacement because patient had undergone two open heart surgeries. Following colectomy, a good clinical...
We report a case of late multiple stent fractures following the deployment sirolimus-eluting stents (SESs) for diffuse right coronary artery (RCA) stenosis. A 44-year-old male with hyperlipidemia was referred to our hospital acute myocardial infarction (AMI). Percutaneous intervention (PCI) performed total occlusion proximal segment RCA, and 5 SESs were consecutively implanted long, stenotic lesions. follow-up angiography (CAG) 8 months later revealed strut in middle all stents, except most...
Pacing-induced cardiomyopathy occasionally occurs in patients undergoing pacemaker implantation. Although compared with right ventricular (RV) apical pacing, RV septal pacing can attenuate left dyssynchrony; the success rate of lead placement on septum using stylet system is low. Additionally, no randomised controlled trial has addressed issue regarding accuracy and delivery catheter systems. This study hypothesises that a newly available improve septum.In multicentre, prospective,...
Abstract Background: Protection from lethal ventricular arrhythmias leading to sudden cardiac death (SCD) is a crucial challenge after acute myocardial infarction (AMI). Cardiac sympathetic and parasympathetic activity can be noninvasively assessed using heart rate variability (HRV) turbulence (HRT). The EMBODY trial was designed determine whether the Sodium–glucose cotransporter 2 (SGLT2) inhibitor improves nerve activity.Methods: This prospective, multicenter, randomized, double-blind,...
Cardiac resynchronization therapy (CRT) improves cardiac function by correcting electrical dyssynchrony in patients with symptomatic heart failure (HF). However, current guidelines focus on QRS interval alone respect to dyssynchrony. We implanted CRT a patient of 126 ms left anterior hemiblock because temporary pacing study before showed correction hemodynamic improvement via at the electrically delayed site alone.
Some patients who undergo implantation of cardiac resynchronization therapy with defibrillator (CRT-D) survive long enough, thus requiring CRT-D battery replacement. Defibrillator might become unnecessary in have had significant clinical improvement and recovery left ventricular ejection fraction (LVEF) after implantation.Forty-nine needed replacement a were considered for exchange pacemaker (CRT-P) if they met the following criteria: LVEF >45%; indication an implantable cardioverter was...
Abstract Introduction The Mt. FUJI multicenter trial demonstrated that a delivery catheter system had higher rate of successful right ventricular (RV) lead deployment on the RV septum (RVS) than conventional stylet system. In this subanalysis trial, we assessed differences in electrocardiogram (ECG) parameters during pacing between and their associations with tip positions. Methods Among 70 patients enrolled Mt ECG parameters, positions, depth inside by computed tomography were compared...
Abstract Background The Mt FUJI study was a multicenter, prospective, randomized, single‐blind, controlled trial comparing delivery catheter‐based and stylet‐based right ventricular (RV) lead placement at the RV septum. This extended follow‐up duration to 1 year after implantation. Methods Seventy patients with pacemaker indications for atrioventricular block were randomly assigned catheter stylet groups. We compared mid‐term efficacy safety between two groups primary outcome change in left...
Abstract Background Cardiac resynchronization therapy (CRT) reduces cardiac electrical dyssyncrhony and improves clinical outcomes in selected symptomatic patients with left ventricular (LV) systolic dysfunction. However, after conventional CRT (Bi-V) have residual dyssynchrony. multi-site pacing has gained attention to improve short-term outcome refractory BiV. long-term follow up is still uncertain. We evaluated the efficacy of triple-site stimulation (Tri-V), involving 2 LV lead...