A5002817760- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Extraction and Separation Processes
- Cardiac electrophysiology and arrhythmias
- Radioactive element chemistry and processing
- Silicon and Solar Cell Technologies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Integrated Circuits and Semiconductor Failure Analysis
- Advanced MRI Techniques and Applications
- Metal Extraction and Bioleaching
- Venous Thromboembolism Diagnosis and Management
- Conservation, Biodiversity, and Resource Management
- Semiconductor materials and devices
- Catalysis and Hydrodesulfurization Studies
- Land Use and Ecosystem Services
- Cardiac Valve Diseases and Treatments
- Remote Sensing and LiDAR Applications
- Ecology and Vegetation Dynamics Studies
- ECG Monitoring and Analysis
- Forest ecology and management
- Minerals Flotation and Separation Techniques
- Catalysis for Biomass Conversion
- Corrosion Behavior and Inhibition
Hamamatsu University School of Medicine
2012-2024
University of Lübeck
2019-2023
Sumitomo Heavy Industries (Japan)
2016-2022
University Hospital Schleswig-Holstein
2019-2022
Hamamatsu University Hospital
2014-2022
Forestry and Forest Products Research Institute
2007-2021
Bio-oriented Technology Research Advancement Institution
2021
National Agriculture and Food Research Organization
2021
German Centre for Cardiovascular Research
2021
Kansai University
1986-2020
Catheter ablation for atrial fibrillation (AF) treatment provides effective and durable pulmonary vein isolation (PVI) is associated with encouraging clinical outcome. A novel CF sensing temperature-controlled radiofrequency (RF) catheter allows very high-power short-duration (vHP-SD, 90 W/4 s) aiming a potentially safer, more faster ablation. We thought to evaluate preliminary safety efficacy of vHP-SD PVI utilizing catheter. The data was compared conventional power-controlled index (AI)...
The very high-power short-duration (vHP-SD) radiofrequency (RF) ablation concept of atrial fibrillation (AF) treatment by pulmonary vein isolation (PVI) aims for safer, more effective, and faster procedures. Utilizing conventional ablation, the 'close protocol' has been verified. Since lesion formation vHP-SD creates wider but shallower lesions we adapted close protocol to an individualized tighter 'very-close 3-4 mm inter-lesion distance (ILD) at anterior 5-6 posterior aspect left atrium...
Our study aimed to investigate both the clinical implications of late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) and relation LGE findings in patients with Takotsubo cardiomyopathy (TTC). We evaluated 20 consecutive (2 men, 18 women; median age, 77 years; interquartile range [IQR] 67-82 years) who were admitted our hospital diagnosis TTC. CMR was performed within 1 week after admission, follow-up studies conducted 1.5 6 months later. In 8 patients, imaging during...
Abstract Background Left atrial appendage closure (LAAC) has emerged as an alternative to oral anticoagulation (OAC) for stroke prevention in patients with fibrillation (AF). OAC treatment been proven feasible mild‐to‐moderate chronic kidney disease (CKD). In contrast, the optimal antithrombotic management of AF end‐stage renal (ESRD) is unknown and LAAC not these prospective randomized clinical trials. Objectives The objective this study evaluate safety efficacy ESRD. Methods Patients...
We present a case of pulmonary arterial hypertension (PAH), which is potentially related to treatment with dasatinib (Sprycel(®)). A 61-year-old woman, who had been treated for 27 months chronic myeloid leukemia (CML), visited our hospital complaining dyspnea. In right heart catheterization, her mean pressure was 35 mmHg. After other possible etiologies cause PAH were excluded, the patient diagnosed as dasatinib-related PAH. As notified by U.S. Food and Drug Administration (FDA) in October...
In this study, we demonstrate changes in leaf morphological and physiological traits with tree height from dark understory to bright canopy conditions various species the Cambodian tropical dry evergreen forest. The vegetation mainly consisted of Dipterocarpaceae Myristicaceae trees usually reached 30-40 m height. We investigated 25 individuals 18 ranging 0.8 33 measured photosynthetic rate, stomatal conductance respiration rate for 3 5 leaves per sampling position early season. All were...
Purpose To examine how left ventricular (LV) volume and function affect flow dynamics by analyzing 3D intra-LV vortex features using 4D-Flow. Materials Methods Twenty-one patients with preserved (LVEF > 60%) 14 impaired LV < 40%) underwent 4D-Flow (at 3T). Results In function, the vortices developed in both early late diastolic phases. The shift of inflow vectors at basal toward posterior-lateral side mid-ventricular turn outflow could explain clearer formation phase. during phase located...
Cardiac involvement in systemic sclerosis (SSc) is considerably frequent autopsy, but the early identification clinically difficult. Recent advantages cardiac magnetic resonance (CMR) enabled to detect myocardial fibrotic scar as late gadolinium enhancement (LGE). We aimed examine prevalence and distribution of LGE patients with SSc, associate them clinical features, electrocardiographic abnormalities function. Forty SSc (58 ± 14 years-old, 35 females, limited/diffuse 25/15, disease duration...
Background:The intra-left atrial (LA) blood flow from pulmonary veins (PVs) to the left ventricle (LV) changes under various conditions and might affect global cardiac function. By using phase-resolved 3-dimensional cine phase contrast magnetic resonance imaging (4D-Flow), intra-LA vortex formation was visualized factors affecting dynamics were examined.Methods Results:Thirty-two patients with or without organic heart diseases underwent 4D-Flow transthoracic echocardiography. The velocity...
Radiofrequency (RF)-based pulmonary vein isolation (PVI) results in a favorable clinical outcome, although its complexity demands long learning curve. Balloon-based systems have been developed to possibly solve these limitations. The 2nd-generation laser balloon (LB2) offers optimized features for improved tissue contact and visibility. We determined the safety, efficacy curve of LB2 PVI.
Pulmonary vein isolation has become a cornerstone treatment for catheter ablation of atrial fibrillation (AF). Recent reports show that additional targeting low-voltage zones reduces AF recurrence. However, the pre-procedural predictors remain elusive. We retrospectively enrolled 359 patients (mean age 63.7 ± 10.8 years; 73 females; and 149 had persistent fibrillation) who underwent left (LA) voltage mapping during sinus rhythm or pacing. Low-voltage were defined as area > 5 cm 2 with...
Background Hypertrophic cardiomyopathy (HCM) is often concomitant with sleep-disordered breathing (SDB), which can cause adverse cardiovascular events. Although an appropriate approach to SDB prevents cardiac remodelling, detection of in patients HCM remains suboptimal. Thus, we aimed develop a machine learning-based discriminant model for HCM. Methods In the present multicentre study, consecutively registered and performed nocturnal oximetry. The outcome was high Oxygen Desaturation Index...
Data reporting a head-to-head comparison between Amulet and Watchman devices are scarce. The aim of this study was to compare the Watchman™ versus Amulet™ left atrial appendage closure (LAAC) in consecutive, industry-independent registry.Patients who underwent LAAC using or from January 2014 December 2019 at University Heart Center Lübeck, Germany were included present analysis. Primary endpoints periprocedural complications (in-hospital death, pericardial tamponade, device embolization,...
The paper is concerned with identification algorithms of Wiener-Hammerstein nonlinear model in frequency domain. By approximately modeling the nonlinearity by polynomial or spline functions, an iterative algorithm proposed to obtain two linear dynamical elements as well static element. A new efficient predistortion scheme for compensating distortion a high power amplifier given based on method.
Although previous studies have suggested a certain prevalence of Fabry disease (FD) in left ventricular hypertrophy (LVH) patients, the screening FD is difficult because its wide-ranging clinical phenotypes. We aimed to clarify utility combined measurement plasma globotriaosylsphingosine (lyso-Gb3) concentration and α-galactosidase A activity (α-GAL) as primary unexplained LVH patients.