A5003475983- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Hemophilia Treatment and Research
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Kidney Injury Research
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Dialysis and Renal Disease Management
- Peripheral Artery Disease Management
- Diabetes Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Orthopaedic implants and arthroplasty
- Hemodynamic Monitoring and Therapy
- Electrolyte and hormonal disorders
- Chronic Myeloid Leukemia Treatments
Nippon Medical School
2014-2025
Nippon Medical School Hospital
2014-2025
Shibuya University Network
2020-2024
The University of Tokyo
2022
Amyloidosis Foundation
2021
Research Network (United States)
2021
NTT Medical Center
2020
JA Toride Medical Center
2020
NanoMedical Systems (United States)
2018
Abstract Background Protection from lethal ventricular arrhythmias leading to sudden cardiac death (SCD) is a crucial challenge after acute myocardial infarction (AMI). Cardiac sympathetic and parasympathetic activity can be noninvasively assessed using heart rate variability (HRV) turbulence (HRT). The EMBODY trial was designed determine whether the Sodium–glucose cotransporter 2 (SGLT2) inhibitor improves nerve activity. Methods This prospective, multicenter, randomized, double-blind,...
BACKGROUND: The absence of practice standards in vasoactive agent usage for acute decompensated heart failure has resulted significant treatment variability across hospitals, potentially affecting patient outcomes. This study aimed to assess temporal trends and institutional differences vasodilator inotrope/vasopressor utilization among patients with failure, considering their clinical phenotypes. METHODS: Data were extracted from a government-funded multicenter registry covering the Tokyo...
Blood flow imaging becomes an emerging trend in cardiology with the recent progress computer technology. It not only visualizes colorful velocity streamlines but also quantifies mechanical stress on cardiovascular structures; thus, it can provide detailed inspections of pathophysiology diseases and predict prognosis functions. Clinical applications include comprehensive assessment hemodynamics cardiac functions echocardiography vector mapping (VFM), 4D MRI, surgical planning as a simulation...
ABSTRACT Alcohol septal ablation (ASA) is an established treatment for hypertrophic obstructive cardiomyopathy (HOCM). However, conventional techniques may be challenging in cases with complex branch anatomy, including hairpin curves, extremely small branches, and acute angle bifurcations. We present three innovative catheter that expand the applicability of ASA these anatomical scenarios. The double balloon technique overcomes curves proximal while perfusion microcatheter enables branches....
Objective The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on global healthcare systems. Some studies have reported the negative of COVID-19 ST-elevation myocardial infarction (STEMI) patients; however, in Japan remains unclear. This study investigated STEMI patients admitted to an academic tertiary-care center Tokyo, Japan. Methods In this retrospective, observational, cohort study, we included 398 consecutive who were our institute from January 1, 2018, March...
Abstract Aims Fractional excretion of urea nitrogen (FEUN), used to differentiate the cause acute kidney injury, has emerged as a useful fluid index in patients with heart failure (HF). We hypothesized that FEUN could be identifying worsening renal function (WRF) associated poor outcomes HF (AHF). Methods and results Overall, 1103 AHF (median age, 78 years; male proportion, 60%) were categorized into six groups according presence WRF values (low, ≤32.1%; medium, >32.1% ≤38.0%; high,...
Abstract Aims Maintenance of euvolaemia with diuretics is critical in heart failure (HF) patients chronic kidney disease (CKD); however, it challenging because no reliable marker volume status exists. Fractional excretion urea nitrogen (FEUN) a useful index renal failure. We aimed to examine whether FEUN surrogate for risk stratification HF CKD. Methods and results examined 516 CKD (defined as discharge estimated glomerular filtration rate < 60 mL/min/1.73 m 2 ) whose was measured at...
Although B-type natriuretic peptide (BNP) and highly sensitive cardiac troponin T (cTnT) are useful for the evaluation of clinical features in various cardiovascular diseases, there comparatively few data regarding utility these parameters patients with hypertrophic obstructive cardiomyopathy (HOCM). The goal this study was to assess association between BNP, cTnT HOCM.Cross-sectional surveyThe relationship end points echocardiographic investigated.This included 102 consecutive outpatients...
Non-cardiac surgery for hypertrophic obstructive cardiomyopathy (HOCM) is considered to require meticulous perioperative care. β-blockers are the first-line drugs patients with HOCM, and they play a key role in preventing cardiovascular complications The bisoprolol transdermal patch has recently become available Japan, it useful who unable take oral medication during aim of this case series was assess hemodynamic features HOCM used care non-cardiac surgery.Between August 2016 2018, we...
Heart failure with preserved ejection fraction (HFpEF) renal dysfunction (RD) is considered to be a specific phenotype of HFpEF. This study aimed compare the clinical characteristics and prognostic factors for in-hospital mortality between HFpEF-diagnosed patients without RD.
Alcohol septal ablation (ASA) is a treatment option in patients with drug-refractory symptomatic hypertrophic obstructive cardiomyopathy (HOCM). In many patients, right bundle branch block (RBBB) develops during ASA because branches supply the branch. However, clinical significance of procedural RBBB uncertain.
Careful evaluation, including provocation tests, is needed to specify an indication for septal reduction therapy in patients with drug-refractory hypertrophic obstructive cardiomyopathy. This study aimed evaluate the outcome of alcohol ablation (ASA) using intravenous nitroglycerin test (IV-NTG). Of consecutive 156 patients, after excluding cases severe valvular disease and repeat therapy, we investigated clinical characteristics labile obstruction (n = 32) outcomes ASA IV-NTG test;...