A5005044418- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Migraine and Headache Studies
- Diabetic Foot Ulcer Assessment and Management
- Multiple Sclerosis Research Studies
- Sympathectomy and Hyperhidrosis Treatments
- Long-Term Effects of COVID-19
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Anesthesia and Sedative Agents
- Diet and metabolism studies
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience of respiration and sleep
- COVID-19 Clinical Research Studies
- Trigeminal Neuralgia and Treatments
- Anesthesia and Neurotoxicity Research
- Tryptophan and brain disorders
- Sleep and Wakefulness Research
- Head and Neck Surgical Oncology
- Neurological and metabolic disorders
- Restless Legs Syndrome Research
University of Udine
2020-2025
Ospedale Santa Maria della Misericordia di Udine
2022-2025
The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding ketogenic diet. However, less exists for Low-Glycemic Index Diet and 2:1 KD. This retrospective single-center real-life study aims to evaluate a diet Low-Glycemic-index chronic high-frequency episodic migraine.Sixty patients with were treated either (39 patients) or (21 three months. We collected data on frequency intensity MIDAS HIT-6 scores through headache diary. Anthropometric...
Abstract Some patients with large vessel occlusion (LVO) achieve insufficient clinical improvement (futile recanalization, FR) after intravenous thrombolysis (IVT) during inter-hospital transfer for thrombectomy, while others show good outcomes (effective ER). This study assessed FR and ER rates among treated IVT at non-thrombectomy primary stroke centers (PSCs) aimed to identify predictors of FR. We analyzed data from two PSC registries (2016–2022). Inclusion criteria: treatment, anterior...
Stress hyperglycemia may impair outcomes in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy (MT). The glucose-to-glycated hemoglobin ratio (GAR) was used to measure stress hyperglycemia. Data from our database of consecutive admitted the Udine University Hospital AIS who were treated MT between January 2015 and December 2020 retrospectively analyzed. We included 204 study stratified them into four groups according quartiles GAR (Q1-Q4). higher index, more severe...
Mechanical thrombectomy (MT) is the first line treatment in acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Approximately half of patients treated with MT does not have a favorable outcome 3 months after stroke. The aim this study was identify predictors futile recanalization (FR) LVO MT.A retrospective analysis consecutive anterior circulation who underwent MT. Patients TICI score 2b or were included. We distinguished two groups, FR and meaningful (MR), according patients'...
Migraine patients are frequently affected by sleep complaints. The ketogenic diet (KD) is an option for the treatment of migraine. Our aim was: 1) to assess effects KD on complaints in migraine and 2) verify if changes were related headache symptoms.From January 2020 July 2022 we consecutively enrolled 70 who treated with as a preventive therapy. We collected information regarding: anthropometric measures; intensity, frequency disability; 3) subjective complaints, i.e. insomnia, quality,...
Although stress hyperglycemia represents a main risk factor for poor outcome among patients with acute ischemic stroke (AIS) undergoing recanalization therapy, we have limited information regarding possible influence of the premorbid diabetic status on this association. We recruited consecutive admitted to Udine University Hospital AIS who were treated intravenous thrombolysis (IVT) from January 2015 September 2020. On basis status, our sample was composed 130 and 371 without diabetes. The...
Introduction It is unknown whether alteplase effective and safe in patients with mild acute ischemic stroke (AIS). Determining symptoms are “disabling” or not a crucial factor the management of these patients. This study aimed to investigate efficacy safety mild, non-disabling AIS. Methods We included all consecutive admitted for AIS at our institution from January 2015 May 2022 who presented baseline NIHSS score 0–5 fit criteria receive intravenous thrombolysis. In order select only...
Background: Admission hyperglycemia impairs outcome in acute ischemic stroke (AIS) patients undergoing mechanical thrombectomy (MT). Since AIS represents a dynamic condition, we tested whether the patterns of hyperglycemia, defined as blood glucose levels > 140 mg/dl, affect outcomes these patients. Methods: We retrospectively analyzed data 200 consecutive with prospective follow-up. Based on level, were distinguished into 4 groups: (1) persistent normoglycemia; (2) at baseline only; (3)...
(1) Background: More than one-third of patients with meningiomas experience at least one seizure during the course their disease, and in 20–50% cases, represents onset symptom. After surgery, up to 30% continue have seizures, while others may them later; (2) Methods: The study analyzed retrospectively risk factors for pre-operative seizures a large cohort 358 who underwent surgery newly diagnosed brain meningioma; (3) Results: We identified age, peritumor edema, location as onset. Patients...
Introduction Migraine and sleep share a complex unclear relationship. Poor may trigger migraine attacks; migraine, in turn, is frequently associated with disorders. Few previous studies used questionnaires to assess changes patients who were treated migraine-preventive medications (MPMs). More extensive polysomnography (PSG)-based for this purpose not available. Objective To investigate possible erenumab, using validated home-PSG. Methods This observational, prospective, open-label pilot...
Multiple sclerosis is a chronic, autoimmune-mediated, demyelinating disease whose pathogenesis remains to be defined. In past years, in consideration of constantly growing number patients diagnosed with multiple sclerosis, the impacts different environmental factors have been largely studied. Alterations gut microbiome composition and intestinal barrier permeability suggested play an essential role regulation autoimmunity. Thus, increased efforts are being conducted demonstrate complex...
To date, very few studies focused their attention on efficacy and safety of recanalisation therapy in acute ischemic stroke (AIS) patients with cancer, reporting conflicting results. We retrospectively analysed data from our database consecutive admitted to the Udine University Hospital AIS that were treated therapy, i.e. intravenous thrombolysis (IVT), mechanical thrombectomy (MT), bridging January 2015 December 2019. compared 3-month dependency, mortality, symptomatic intracranial...
Stroke has been described as a COVID-19 complication. However, its occurrence rate, risk factors, and causal relationships are still not well established.
Different neurological complications associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection have been widely documented. Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated demyelinating disorder, described within spectrum of manifestations COVID-19. Herein, we describe case adult-ADEM presenting diplopia and slowly progressive ataxia developed one month after SARS-CoV-2 infection. Brain magnetic resonance imaging (MRI) revealed multifocal...
Background: Few studies compare the clinical effectiveness of three anti-CGRP mAbs. Moreover, no their efficacy during suspension and reprisal. Our study aimed to migraine frequency, intensity, symptomatic medication intake first year therapy, a 1-month period, 3-month drug Methods: A total 160 migraineurs (chronic high-frequency episodic) were treated with mAbs (49 fremanezumab, 55 erenumab, galcanezumab) for 12 months. They discontinued therapy 1 month then reprised therapy. In groups, we...