Andrea Surcinelli
A5091778912- Multiple Sclerosis Research Studies
- Acute Ischemic Stroke Management
- Long-Term Effects of COVID-19
- Stroke Rehabilitation and Recovery
- Peripheral Neuropathies and Disorders
- Diabetic Foot Ulcer Assessment and Management
- Migraine and Headache Studies
- Rheumatoid Arthritis Research and Therapies
- Olfactory and Sensory Function Studies
- Autoimmune and Inflammatory Disorders Research
- Retinal and Optic Conditions
- Polyomavirus and related diseases
- Systemic Lupus Erythematosus Research
- Venous Thromboembolism Diagnosis and Management
- Biochemical Analysis and Sensing Techniques
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Syncope and Autonomic Disorders
- COVID-19 and Mental Health
- Sympathectomy and Hyperhidrosis Treatments
- Acute Lymphoblastic Leukemia research
- Cerebrovascular and Carotid Artery Diseases
- NF-κB Signaling Pathways
- Immunotherapy and Immune Responses
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
Ospedale "Santa Maria delle Croci" di Ravenna
2024-2025
Azienda Unità Sanitaria Locale Della Romagna
2025
University of Udine
2020-2022
Ospedale Santa Maria della Misericordia di Udine
2022
Abstract Objective To report clinical and electroneuromyographic (ENMG) characteristics of patients affected by severe COVID-19 infection, evaluated for muscular weakness. Materials methods ENMGs performed evaluation diffuse weakness in who could not be discharged from semi-intensive care COVID unit because difficulties ventilation weaning were reviewed. Patients with infection had undergone endotracheal intubation able to co-operate considered. ENMG protocol was focused on...
By the end of 2019, severe acute respiratory syndrome coronavirus 2 rapidly spread all over world impacting mental health and sleep habits. Insomnia, impaired quality, circadian rhythm alterations were observed during pandemic, especially among healthcare workers in patients with post-acute COVID-19. Sleep disruption may induce a pro-inflammatory state associated an impairment immune system function.
Background: Characterizing Cladribine tablets prescription pattern in daily clinical practice is crucial for optimizing multiple sclerosis (MS) treatment. Objectives: To describe efficacy, safety profile and new disease-modifying therapy (DMT) prescriptions following Design: Independent retrospective cohort study patients followed at six Italian MS centres. Methods: Patients diagnosed with relapsing (RMS) according to 2017 McDonald criteria, who initiated between January 2019 May 2023, were...
Stress hyperglycemia may impair outcomes in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy (MT). The glucose-to-glycated hemoglobin ratio (GAR) was used to measure stress hyperglycemia. Data from our database of consecutive admitted the Udine University Hospital AIS who were treated MT between January 2015 and December 2020 retrospectively analyzed. We included 204 study stratified them into four groups according quartiles GAR (Q1-Q4). higher index, more severe...
The COVID-19 pandemic raised concern amongst clinicians that disease-modifying therapies (DMT), particularly anti-CD20 monoclonal antibodies (mAb) and fingolimod, could worsen in people with multiple sclerosis (pwMS). This study aimed to examine DMT prescribing trends pre- post-pandemic onset.
Although stress hyperglycemia represents a main risk factor for poor outcome among patients with acute ischemic stroke (AIS) undergoing recanalization therapy, we have limited information regarding possible influence of the premorbid diabetic status on this association. We recruited consecutive admitted to Udine University Hospital AIS who were treated intravenous thrombolysis (IVT) from January 2015 September 2020. On basis status, our sample was composed 130 and 371 without diabetes. The...
Background It remains unclear whether routine cerebrospinal fluid (CSF) parameters can serve as predictors of multiple sclerosis (MS) disease course. Methods This large-scale cohort study included persons with MS CSF data documented in the MSBase registry. to predict time reach confirmed Expanded Disability Status Scale (EDSS) scores 4, 6 and 7 annualised relapse rate first 2 years after diagnosis (ARR2) were assessed using (cox) regression analysis. Results In total, 11 245 participants...
Backgroundin the early stages of Multiple Sclerosis (MS), initiating high-efficacy disease-modifying therapy (HE DMTs) may represent an optimal strategy for delaying neurological damage and long-term disease progression, especially in highly active MS patients (HAMS). Natalizumab (NAT) Ocrelizumab (OCR) are recognized as HE DMTs with significant anti-inflammatory effects. This study investigates NEDA-3 achievement treatment-naïve HAMS receiving NAT or OCR over three years.Methodswe...
Background: Admission hyperglycemia impairs outcome in acute ischemic stroke (AIS) patients undergoing mechanical thrombectomy (MT). Since AIS represents a dynamic condition, we tested whether the patterns of hyperglycemia, defined as blood glucose levels > 140 mg/dl, affect outcomes these patients. Methods: We retrospectively analyzed data 200 consecutive with prospective follow-up. Based on level, were distinguished into 4 groups: (1) persistent normoglycemia; (2) at baseline only; (3)...
Intravenous thrombolysis (IVT) in patients with a low National Institutes of Health Stroke Scale (NIHSS) score 0–5 remains controversial. IVT should be used mild but nevertheless disabling symptoms. We hypothesize that response to “mild stroke” may depend on their level functional dependence (FD) at hospital admission. The aims our study were investigate the effect and explore role FD influencing IVT. This was retrospective analysis prospectively collected database, including 389 stratified...
Background Neuromyelitis optica spectrum disorder (NMOSD) can be categorised into aquaporin-4 antibody (AQP4-IgG) NMOSD or seronegative NMOSD. While our knowledge of AQP4-IgG has evolved significantly in the past decade, remains less understood. This study aimed to evaluate predictors relapses and treatment responses Methods was a multicentre, international, retrospective cohort using MSBase registry. Recurrent relapse risk assessed an Andersen-Gill model first evaluated Cox proportional...
Introduction Migraine and sleep share a complex unclear relationship. Poor may trigger migraine attacks; migraine, in turn, is frequently associated with disorders. Few previous studies used questionnaires to assess changes patients who were treated migraine-preventive medications (MPMs). More extensive polysomnography (PSG)-based for this purpose not available. Objective To investigate possible erenumab, using validated home-PSG. Methods This observational, prospective, open-label pilot...
To date, very few studies focused their attention on efficacy and safety of recanalisation therapy in acute ischemic stroke (AIS) patients with cancer, reporting conflicting results. We retrospectively analysed data from our database consecutive admitted to the Udine University Hospital AIS that were treated therapy, i.e. intravenous thrombolysis (IVT), mechanical thrombectomy (MT), bridging January 2015 December 2019. compared 3-month dependency, mortality, symptomatic intracranial...
Gustatory (GD) and olfactory (OD) dysfunctions are the most frequent neurological manifestations of COVID-19. We used mental imagery as an experimental psychological paradigm to access gustatory brain representations in 80 Italian COVID-19 adult patients (68.75% reported both OD GD). with + GD have a significantly selectively decreased vividness odor taste imagery, indicating that has effect on their chemosensory representations. length type influenced status were become all negative at time...
To evaluate the prevalence of hyposmia and dysgeusia in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection their temporal relationship onset other symptoms.
The relationship between coronavirus disease 2019 (COVID-19) infection and multiple sclerosis (MS) relapse progression remains unclear. Previous studies are limited by small sample sizes most lack a propensity-matched control cohort.
Introduction: In cluster headache, the efficacy of suboccipital steroid injection is notable within a few days, although data are available about duration efficacy. A combination treatment, consisting plus pulsed radiofrequency, could potentially lead to long-term benefit. Evidence radiofrequency greater occipital nerve lacking. Patients and Methods: We retrospectively describe series four headache patients treated with nerve. Results: All achieved 50% reduction in attack frequency 7 days...