A5041886681- Sarcoma Diagnosis and Treatment
- Soft tissue tumor case studies
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Gastrointestinal Tumor Research and Treatment
- Tumors and Oncological Cases
- Soft tissue tumors and treatment
- Chronic Lymphocytic Leukemia Research
- Cell Adhesion Molecules Research
- Chromatin Remodeling and Cancer
- Protein Degradation and Inhibitors
- Urologic and reproductive health conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Oral and Maxillofacial Pathology
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Electric Motor Design and Analysis
- Colorectal Cancer Surgical Treatments
- Lymphoma Diagnosis and Treatment
- Cystic Fibrosis Research Advances
- Glycosylation and Glycoproteins Research
- Cancer and Skin Lesions
- Testicular diseases and treatments
Fondazione IRCCS Istituto Nazionale dei Tumori
2016-2025
ASST Fatebenefratelli Sacco
2021-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2012-2020
Istituto Ortopedico Galeazzi
2016-2020
Santissima Trinità
2018
Ospedale di Circolo e Fondazione Macchi
2012-2015
Emory University
2014
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2009-2013
The University of Texas MD Anderson Cancer Center
2011-2013
IRCCS Humanitas Research Hospital
2013
Purpose Integration of numerous prognostic variables not included in the conventional staging retroperitoneal soft tissue sarcomas (RPS) is essential providing effective treatment. The purpose this study was to build a specific nomogram for predicting postoperative overall survival (OS) and disease-free (DFS) patients with primary RPS. Patients Methods Data registered three institutional prospective sarcoma databases were used. We localized RPS resected between 1999 2009. Univariate (Kaplan...
In Brief Purpose: To improve understanding of what is adequate in local treatment extremity soft tissue sarcomas (ESTS), to maximize the ratio between control, limb preservation and prognosis. Patient Methods: Nine hundred ninety-seven consecutive patients affected by primary ESTS were reviewed. Size, depth, histotype grade tumor, margin status (R0, R1, R2) surgical resection, adjuvant treatments analyzed. Univariable multivariable analysis carried out. For subgroup R1 resection...
BACKGROUND A role for the serine to phenylalanine substitution at codon 45 (the S45F mutation) in catenin (cadherin‐associated protein) β‐1 ( CTNNB1 ) gene as a molecular predictor of local recurrence patients with primary, sporadic desmoid tumor (DT) has been reported. To confirm previous data, authors evaluated correlation between mutation type and this multi‐institutional, retrospective study. METHODS Patients DT who underwent macroscopic complete surgical resection were included....
The aim of the present work was to improve understanding impact malignancy grade and myogenic/rhabdomyoblastic differentiation on natural course retroperitoneal liposarcoma. All consecutive patients affected by primary well-differentiated (WD)/dedifferentiated (DD) liposarcoma, surgically treated at our institution between January 2002 December 2011, were retrospectively evaluated. Tumors stained for mdm2 5 myogenic markers (smooth muscle actin-α, h-caldesmon, calponin, desmin, myogenin)....
BACKGROUND: Pleomorphic liposarcoma (PLS) is a rare high-grade sarcoma that has lipoblastic differentiation. In this study, the authors evaluated PLS natural history, patient outcomes, and commonly deregulated protein biomarkers. METHODS: Medical records from patients (n = 155) who had 1993 to 2010 were reviewed. Univariate multivariate analyses conducted identify independent prognosticators. A tissue microarray (TMA) 56 specimens) was constructed for immunohistochemical analysis of...
Many women who present with desmoid-type fibromatosis (DF) have had a recent pregnancy. Long-term data about disease behavior during and after pregnancy are lacking.To investigate the possible relationship between DF pregnancy.A cohort of was identified from 4 sarcoma centers. Four groups were identified: diagnosis (A); delivery (B); clinically evident (C); resected before (D). Progression/regression rates, recurrence rates resection, obstetric outcomes analyzed.Ninety-two included....
Abstract Purpose: To prospectively assess the behavior of primary sporadic (not familial adenomatous polyposis–associated) desmoid fibromatosis (DF) managed by active surveillance (AS). Experimental Design: This is an Italian prospective, multicenter, observational study (NCT 02547831) including patients ≥16 years with DF at any site. Patients were assessed Response Evaluation Criteria in Solid Tumor (RECIST) version 1.1. Primary endpoint was progression-free survival (PFS) 3 years....
Abstract BACKGROUND. Myxoid liposarcoma (MLPS), a disease especially of young adults with potential for local recurrence and metastasis, currently lacks solid prognostic factors therapeutic targets. The authors this report evaluated the natural history outcome patients MLPS commonly deregulated protein biomarkers. METHODS. Medical records were retrospectively reviewed who presented to authors' institution localized (n = 207) or metastatic 61) (1990 2010). A tissue microarray patient...
Purpose Today, surgery and radiation therapy have a limited role in desmoid-type fibromatosis. Different systemic treatments were shown to be effective. Herein, we report on our institutional experience with low-dose methotrexate (MTX) + vinca alkaloids this disease over the last 25 years. Methods We retrospectively reviewed data from all adult patients sporadic fibromatosis treated MTX at institution between 1989 2014. Results identified 75 vinblastine (40%), vinorelbine (57%), alone (3%)....