A5044146626- Sarcoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Neuroblastoma Research and Treatments
- CAR-T cell therapy research
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Testicular diseases and treatments
- Bone Tumor Diagnosis and Treatments
- Neurofibromatosis and Schwannoma Cases
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Genetic factors in colorectal cancer
- Immunotherapy and Immune Responses
- Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Cutaneous Melanoma Detection and Management
Fondazione IRCCS Istituto Nazionale dei Tumori
2016-2025
University of Palermo
2002-2024
John Wiley & Sons (United States)
2016-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2023
Clinical Research Organization
2011-2023
Oxfam
2023
Liechtenstein Institute
2023
Hudson Institute
2023
John Wiley & Sons (United Kingdom)
2023
Merck Serono (Italy)
2020
Determine the histologic response-rate (complete versus partial tumor extinction) after single radiofrequency ablation (RFA) of small hepatocellular carcinoma (HCC) arising in cirrhosis. Investigate possible predictors response and assess efficacy safety RFA as a bridge to liver transplantation (OLT).RFA has become elective treatment local control HCC, although data supporting radiologic assessment are rare prospective studies lacking. Prognostic impact repeated for HCC persistence is also...
Retroperitoneal sarcomas (RPS) are rare tumors composed of several well defined histologic subtypes. The aim this study was to analyze patterns recurrence and treatment variations in a large population patients, treated at reference centers.All consecutive patients with primary RPS 6 European 2 North American institutions between January 2002 December 2011 were included. Five, 8, 10-year overall survival (OS) crude cumulative incidence (CCI) local (LR) distant metastasis (DM) calculated....
Objective To evaluate the impact of subtotal (SG) versus total (TG) gastrectomy on oncologic outcome patients with cancer distal stomach from 28 Italian institutions. Summary Background Data There is controversy over whether SG and TG have a different 5-year survival probability half stomach. Methods The present analysis involved 618 randomized during surgery to (315) or (303), provided there was at least 6 cm proximal edge tumor cardia, no intraperitoneal distant spread, it possible remove...
BACKGROUND: Fenretinide, a vitamin A analogue, has been shown to inhibit breast carcinogenesis in preclinical studies. We determined the efficacy of fenretinide preventing second malignancy women with cancer. METHODS: randomly assigned 2972 women, aged 30-70 years, surgically removed stage I cancer or ductal carcinoma situ receive for 5 years either orally (200 mg/day) no treatment. The primary end point was incidence contralateral ipsilateral 7 after randomization. Other points considered...
The authors explored the prognostic factors and clinical outcomes of patients who had malignant peripheral nerve sheath tumors (MPNST) with without neurofibromatosis type 1 (NF-1).Two hundred five localized MPNST underwent surgery at Istituto Nazionale per lo Studio e la Cura dei Tumori (Milan, Italy) over 25 years were reviewed. Forty-six concomitant NF-1 syndrome, 159 did not. Local recurrence, distant metastases, survival rates studied.One thirty presented primary disease, 75 locally...
Purpose Integration of numerous prognostic variables not included in the conventional staging retroperitoneal soft tissue sarcomas (RPS) is essential providing effective treatment. The purpose this study was to build a specific nomogram for predicting postoperative overall survival (OS) and disease-free (DFS) patients with primary RPS. Patients Methods Data registered three institutional prospective sarcoma databases were used. We localized RPS resected between 1999 2009. Univariate (Kaplan...
Selection criteria and benefit of liver transplantation for hepatic metastases from neuroendocrine tumors (NETs) remain uncertain. Eighty-eight consecutive patients with metastatic NETs eligible according to Milan-NET were offered transplant (n = 42) versus nontransplant options 46) depending on list dynamics, patient disposition, age. Tumor burden between groups did not differ. Transplant younger (40.5 vs. 55.5 years; p < 0.001). Long-term outcomes compared after matching made multiple Cox...
To investigate the safety of radical resection for retroperitoneal sarcoma (RPS).The surgical management RPS frequently involves complex multivisceral resection. Improved oncologic outcomes have been demonstrated with this approach compared to marginal excision, but has not shown in a large study population.The Transatlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaborative centers. A combined experience 1007 consecutive resections primary from January 2002...
Background: Clinical trials investigating the potential benefits of perioperative total parenteral nutrition (TPN) for reducing risk surgery in malnourished cancer patients have yielded controversial results. Methods: Ninety elective surgical with gastric or colorectal tumors and weight loss 10% more usual body were randomly assigned to 10 days preoperative 9 postoperative us a simple control group. The daily per kilogram TPN regimen included 34.6 ± 6.3 kcal nonprotein 0.25 0.04 g nitrogen...
To explore the prognostic effect of microscopic marginal status after surgery for extremity soft tissue sarcomas.We analyzed 911 consecutive patients surgically treated throughout a 20-year span at single referral center. Six hundred forty-two were first seen with primary tumor, and 269, locally recurrent tumor. All underwent macroscopically complete resection. Microscopic was negative (tumor size > 1 mm) in 748 positive (</= 163 patients. Median follow-up 107 months.Patients disease had...
Abstract BACKGROUND A nomogram for predicting long term tumor‐specific death in patients with soft tissue sarcoma (STS) was developed at the Memorial Sloan‐Kettering Cancer Center (MSKCC). METHODS To assess performance of MSKCC nomogram, 642 consecutive extremity STS who underwent surgery over a 20‐year span single referral center were analyzed. Nomogram predictions based on tumor size, depth, site, patient age, histologic subtype, and grade. The latter, variance system use MSKCC, classified...